| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0471051 |
| AHNAK | AHNAK nucleoprotein | 0.0357343 |
| EFNA5 | ephrin-A5 | 0.0335334 |
| CDH13 | cadherin 13 | 0.0281679 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0259544 |
| VCL | vinculin | 0.0234578 |
| GLIS3 | GLIS family zinc finger 3 | 0.0227994 |
| INTS6 | integrator complex subunit 6 | 0.0201174 |
| DST | dystonin | 0.019034 |
| ASPH | aspartate beta-hydroxylase | 0.0168009 |
| LOX | lysyl oxidase | 0.0166903 |
| NEK7 | NIMA-related kinase 7 | 0.0165667 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0162875 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.015903 |
| SMYD3 | SET and MYND domain containing 3 | 0.0155277 |
| APP | amyloid beta (A4) precursor protein | 0.0155088 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0152419 |
| PRELID2 | PRELI domain containing 2 | 0.0145389 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0144394 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0143055 |
| HDAC9 | histone deacetylase 9 | 0.0142604 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0141387 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.014063 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0139678 |
| NABP1 | nucleic acid binding protein 1 | 0.0138122 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0137682 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0135874 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0132071 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0131059 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0130673 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0127332 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0126821 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0123528 |
| COL3A1 | collagen, type III, alpha 1 | 0.0121738 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.012166 |
| VMP1 | vacuole membrane protein 1 | 0.0120797 |
| CANX | calnexin | 0.0120426 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0119599 |
| SMAD3 | SMAD family member 3 | 0.0119593 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0117263 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0117061 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0116859 |
| EGFR | epidermal growth factor receptor | 0.0116777 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0115352 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0114374 |
| IPO9 | importin 9 | 0.0108752 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0108676 |
| ANO6 | anoctamin 6 | 0.0108241 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0107736 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0107622 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0106802 |
| DNMBP | dynamin binding protein | 0.0105525 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0105223 |
| RASAL2 | RAS protein activator like 2 | 0.0104332 |
| EHBP1 | EH domain binding protein 1 | 0.0103525 |
| AUTS2 | autism susceptibility candidate 2 | 0.0102522 |
| NAV1 | neuron navigator 1 | 0.0102206 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.010195 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0101831 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.00994201 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0098398 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.00981012 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0096874 |
| AFF3 | AF4/FMR2 family, member 3 | 0.00961088 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00958081 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.00939238 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.00921248 |
| FSTL1 | follistatin-like 1 | 0.00908078 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00893121 |
| KLF12 | Kruppel-like factor 12 | 0.00890321 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00879478 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00877277 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00876233 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00869718 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.00867761 |
| CEP112 | centrosomal protein 112kDa | 0.00859376 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.00858029 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.00853889 |
| TUSC3 | tumor suppressor candidate 3 | 0.00849707 |
| FAT1 | FAT atypical cadherin 1 | 0.00841425 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00840174 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.00838694 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.00834004 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.00825472 |
| RASA2 | RAS p21 protein activator 2 | 0.00815922 |
| NCKAP1 | NCK-associated protein 1 | 0.00799869 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.00796967 |
| LYST | lysosomal trafficking regulator | 0.00794472 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00792389 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.00788817 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.00788287 |
| EXOC4 | exocyst complex component 4 | 0.00787271 |
| NID1 | nidogen 1 | 0.00785388 |
| ADD1 | adducin 1 (alpha) | 0.00784614 |
| SEPTIN9 | septin 9 | 0.00782919 |
| SATB2 | SATB homeobox 2 | 0.00768411 |
| FER | fer (fps/fes related) tyrosine kinase | 0.00766435 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.00764331 |
| PHF14 | PHD finger protein 14 | 0.0076184 |
| CDK13 | cyclin-dependent kinase 13 | 0.00761601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.380494 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.224753 |
| TMSB10 | thymosin beta 10 | -0.169422 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154327 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.111813 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0776626 |
| NDRG1 | N-myc downstream regulated 1 | -0.0748602 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0742872 |
| B2M | beta-2-microglobulin | -0.0719886 |
| S100A10 | S100 calcium binding protein A10 | -0.0710485 |
| S100A6 | S100 calcium binding protein A6 | -0.0679348 |
| LMNA | lamin A/C | -0.062508 |
| HLA-B | major histocompatibility complex, class I, B | -0.0604815 |
| CSTB | cystatin B (stefin B) | -0.0591022 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0583995 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.057266 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0568728 |
| MT2A | metallothionein 2A | -0.0567785 |
| PLAT | plasminogen activator, tissue | -0.0530479 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0525779 |
| PTMA | prothymosin, alpha | -0.051241 |
| POTEF | POTE ankyrin domain family, member F | -0.0474581 |
| FN1 | fibronectin 1 | -0.0461174 |
| MAP1B | microtubule-associated protein 1B | -0.0454481 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0443338 |
| SUCNR1 | succinate receptor 1 | -0.0425753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0422278 |
| TPM4 | tropomyosin 4 | -0.040692 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0382874 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0368187 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0360194 |
| TAGLN2 | transgelin 2 | -0.035599 |
| CD99 | CD99 molecule | -0.0346965 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0346503 |
| S100A4 | S100 calcium binding protein A4 | -0.0341172 |
| UBC | ubiquitin C | -0.0339254 |
| CALR | calreticulin | -0.0336182 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0330021 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0324266 |
| PKM | pyruvate kinase, muscle | -0.0317878 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0306063 |
| FTL | ferritin, light polypeptide | -0.030422 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0299766 |
| PFN1 | profilin 1 | -0.0291461 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0286784 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0278496 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0278092 |
| HLA-C | major histocompatibility complex, class I, C | -0.027566 |
| S100A11 | S100 calcium binding protein A11 | -0.0274596 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0273253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0263594 |
| MX2 | MX dynamin-like GTPase 2 | -0.0259022 |
| PRSS23 | protease, serine, 23 | -0.0255728 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.024975 |
| LOXL2 | lysyl oxidase-like 2 | -0.024248 |
| FOSL1 | FOS-like antigen 1 | -0.0241328 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0239337 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0239047 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0237705 |
| GOLGA4 | golgin A4 | -0.0236755 |
| HLA-A | major histocompatibility complex, class I, A | -0.0233531 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0233491 |
| RTN4 | reticulon 4 | -0.0227816 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0225666 |
| SEC61G | Sec61 gamma subunit | -0.0223975 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0223107 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0222902 |
| MT1X | metallothionein 1X | -0.0221687 |
| KRT81 | keratin 81, type II | -0.0218393 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.02141 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0213888 |
| ADM | adrenomedullin | -0.0210152 |
| RPS6 | ribosomal protein S6 | -0.0209046 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0206084 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0206054 |
| SETD5 | SET domain containing 5 | -0.020055 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0199796 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0198139 |
| RPL35A | ribosomal protein L35a | -0.0196395 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0195542 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0194225 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0193714 |
| H3-3B | H3.3 histone B | -0.0193669 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0191866 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0189225 |
| RPS19 | ribosomal protein S19 | -0.0184063 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0180802 |
| CD109 | CD109 molecule | -0.0178726 |
| ACTG1 | actin gamma 1 | -0.017737 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0177267 |
| FAM162A | family with sequence similarity 162, member A | -0.0176186 |
| SEPTIN7 | septin 7 | -0.0176024 |
| INSIG1 | insulin induced gene 1 | -0.0174348 |
| CCND1 | cyclin D1 | -0.0173712 |
| MYADM | myeloid-associated differentiation marker | -0.0171906 |
| GNAS | GNAS complex locus | -0.0171155 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0171105 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0170594 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0169121 |
| RPS8 | ribosomal protein S8 | -0.0168976 |
