| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.0734864 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0627303 |
| POTEF | POTE ankyrin domain family, member F | 0.0619316 |
| CENPF | centromere protein F, 350/400kDa | 0.0505412 |
| PCBP2 | poly(rC) binding protein 2 | 0.0456589 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0381345 |
| TUBA1B | tubulin, alpha 1b | 0.0351492 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0316223 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0314893 |
| CCN2 | cellular communication network factor 2 | 0.0310554 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0295624 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0291085 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0277963 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0277283 |
| TGM2 | transglutaminase 2 | 0.0273067 |
| ERBIN | erbb2 interacting protein | 0.027266 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.026079 |
| HMGA1 | high mobility group AT-hook 1 | 0.0255172 |
| WDR43 | WD repeat domain 43 | 0.0240873 |
| PFN1 | profilin 1 | 0.0220614 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0218923 |
| ECT2 | epithelial cell transforming 2 | 0.0215756 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0197887 |
| SKIL | SKI-like proto-oncogene | 0.0197296 |
| ZNF638 | zinc finger protein 638 | 0.0192891 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0186538 |
| CENPE | centromere protein E, 312kDa | 0.0178533 |
| LDHA | lactate dehydrogenase A | 0.0175092 |
| ACTG1 | actin gamma 1 | 0.017364 |
| CCDC88A | coiled-coil domain containing 88A | 0.0170591 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0169229 |
| ADIPOR2 | adiponectin receptor 2 | 0.0168582 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.016806 |
| PHF14 | PHD finger protein 14 | 0.016603 |
| RTN4 | reticulon 4 | 0.016594 |
| DIAPH3 | diaphanous-related formin 3 | 0.0164804 |
| FOXM1 | forkhead box M1 | 0.0164768 |
| ACLY | ATP citrate lyase | 0.0164247 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0162635 |
| PTMS | parathymosin | 0.0162203 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0160961 |
| RBMX | RNA binding motif protein, X-linked | 0.0160885 |
| PKM | pyruvate kinase, muscle | 0.0160503 |
| KIF18A | kinesin family member 18A | 0.0158426 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0157705 |
| SON | SON DNA binding protein | 0.0156357 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0156066 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0155966 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0153595 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0152848 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0151858 |
| EDARADD | EDAR-associated death domain | 0.0147787 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0146434 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0144985 |
| HDGF | hepatoma-derived growth factor | 0.0143616 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0140519 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0138028 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0137991 |
| KIF18B | kinesin family member 18B | 0.0137601 |
| TBK1 | TANK-binding kinase 1 | 0.0137191 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0134863 |
| TCP1 | t-complex 1 | 0.0134478 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0133312 |
| ZNF644 | zinc finger protein 644 | 0.0133267 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0133266 |
| ARF4 | ADP-ribosylation factor 4 | 0.0132724 |
| COL5A2 | collagen, type V, alpha 2 | 0.013225 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0131537 |
| TJP1 | tight junction protein 1 | 0.0130903 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0130582 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0129954 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0128705 |
| TUBA1C | tubulin, alpha 1c | 0.0128446 |
| DEK | DEK proto-oncogene | 0.0128432 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0128431 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0126414 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0125509 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0125185 |
| NUP58 | nucleoporin 58 | 0.0124709 |
| MYADM | myeloid-associated differentiation marker | 0.0124648 |
| TPX2 | TPX2, microtubule-associated | 0.0122944 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0122024 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0120891 |
| SLMAP | sarcolemma associated protein | 0.0120869 |
| PTEN | phosphatase and tensin homolog | 0.0120847 |
| RBBP4 | retinoblastoma binding protein 4 | 0.0120415 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0119832 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0118897 |
| ZNF148 | zinc finger protein 148 | 0.0118779 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0118408 |
| KIF23 | kinesin family member 23 | 0.0118013 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0116618 |
| TGOLN2 | trans-golgi network protein 2 | 0.0116324 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | 0.0115506 |
| MACROH2A1 | macroH2A.1 histone | 0.0115165 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0113332 |
| PLS3 | plastin 3 | 0.0112883 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0112417 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0112 |
| YBX1 | Y box binding protein 1 | 0.0111845 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.157681 |
| VIM | vimentin | -0.105763 |
| PCDH7 | protocadherin 7 | -0.0927602 |
| TMSB10 | thymosin beta 10 | -0.088949 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0816523 |
| ANXA1 | annexin A1 | -0.0785059 |
| RPS12 | ribosomal protein S12 | -0.0748362 |
| EHBP1 | EH domain binding protein 1 | -0.0706328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0695688 |
| ASPH | aspartate beta-hydroxylase | -0.0663297 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0635332 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0628821 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0621827 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.060963 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0585089 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.057991 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0579232 |
| TXNRD1 | thioredoxin reductase 1 | -0.0569874 |
| RPS3 | ribosomal protein S3 | -0.0567696 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0546406 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.052893 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0525241 |
| HMGA2 | high mobility group AT-hook 2 | -0.0522893 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0521199 |
| PTMA | prothymosin, alpha | -0.0512772 |
| RPS2 | ribosomal protein S2 | -0.051247 |
| MMP12 | matrix metallopeptidase 12 | -0.0511691 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0498549 |
| RPS8 | ribosomal protein S8 | -0.0477159 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0475701 |
| JMJD1C | jumonji domain containing 1C | -0.0462634 |
| MGAT4C | MGAT4 family, member C | -0.0461561 |
| RPL26 | ribosomal protein L26 | -0.0448028 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0447065 |
| AHNAK | AHNAK nucleoprotein | -0.0443758 |
| RPL12 | ribosomal protein L12 | -0.044103 |
| ZNF804A | zinc finger protein 804A | -0.0425223 |
| RPL19 | ribosomal protein L19 | -0.0425092 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.041336 |
| PCDH9 | protocadherin 9 | -0.0396037 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0391489 |
| RPL23 | ribosomal protein L23 | -0.0391171 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0391132 |
| SYT1 | synaptotagmin I | -0.0388283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0384242 |
| RAB10 | RAB10, member RAS oncogene family | -0.0381566 |
| RPL37A | ribosomal protein L37a | -0.0375671 |
| CANX | calnexin | -0.0364771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0364324 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0359045 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0353084 |
| AREG | amphiregulin | -0.0351497 |
| ZNF217 | zinc finger protein 217 | -0.0350358 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0349467 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0345982 |
| H1-0 | H1.0 linker histone | -0.0345938 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0340533 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0334758 |
| RPL35A | ribosomal protein L35a | -0.0331733 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0329522 |
| RPL36 | ribosomal protein L36 | -0.0328689 |
| NHSL1 | NHS-like 1 | -0.0325652 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0325565 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0325158 |
| RPL38 | ribosomal protein L38 | -0.0319266 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0318826 |
| RPS19 | ribosomal protein S19 | -0.0311169 |
| RPLP2 | ribosomal protein, large, P2 | -0.0310693 |
| KLF6 | Kruppel-like factor 6 | -0.030882 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0307016 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.030536 |
| RPS27A | ribosomal protein S27a | -0.0303444 |
| YBX3 | Y box binding protein 3 | -0.0302748 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0301298 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0301248 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0297778 |
| CLDN1 | claudin 1 | -0.0297082 |
| RPL31 | ribosomal protein L31 | -0.0293875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.029332 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0292028 |
| CUX1 | cut-like homeobox 1 | -0.0292021 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0289135 |
| S100A6 | S100 calcium binding protein A6 | -0.0287849 |
| GOLGB1 | golgin B1 | -0.0287341 |
| FBXO11 | F-box protein 11 | -0.0286046 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0284417 |
| RPS25 | ribosomal protein S25 | -0.0283275 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0282854 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.028081 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0279814 |
| RPL37 | ribosomal protein L37 | -0.0276814 |
| DTNA | dystrobrevin, alpha | -0.027471 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.027379 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0273226 |
| MED13L | mediator complex subunit 13-like | -0.02714 |
| RPL34 | ribosomal protein L34 | -0.0268455 |
| MTAP | methylthioadenosine phosphorylase | -0.0268332 |
| RPL36A | ribosomal protein L36a | -0.0264932 |
| R3HDM2 | R3H domain containing 2 | -0.02643 |
| RPS6 | ribosomal protein S6 | -0.0262776 |
