| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.11087 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0882653 |
| VCL | vinculin | 0.0879372 |
| LSAMP | limbic system-associated membrane protein | 0.066185 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.064072 |
| VMP1 | vacuole membrane protein 1 | 0.0622589 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0558239 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0526535 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0488584 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0460849 |
| NRG1 | neuregulin 1 | 0.0454503 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0447945 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0441555 |
| PLPP1 | phospholipid phosphatase 1 | 0.0428366 |
| PDE10A | phosphodiesterase 10A | 0.0415614 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0410298 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0403744 |
| CDH13 | cadherin 13 | 0.0402395 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0390082 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0389716 |
| RAD51B | RAD51 paralog B | 0.0387168 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0380196 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0372757 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0370157 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0365797 |
| MX2 | MX dynamin-like GTPase 2 | 0.0350478 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0343959 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0342641 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0338707 |
| DNM3 | dynamin 3 | 0.0337286 |
| GLCCI1 | glucocorticoid induced 1 | 0.032954 |
| STK38L | serine/threonine kinase 38 like | 0.0314302 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0310202 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0308463 |
| FRMD4A | FERM domain containing 4A | 0.0304816 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0304619 |
| PTEN | phosphatase and tensin homolog | 0.0302079 |
| KLHL13 | kelch-like family member 13 | 0.0301432 |
| PRKCA | protein kinase C, alpha | 0.0301161 |
| RIGI | RNA sensor RIG-I | 0.0290858 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0285297 |
| SIK2 | salt-inducible kinase 2 | 0.0282291 |
| RNF213 | ring finger protein 213 | 0.0280988 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0277542 |
| FN1 | fibronectin 1 | 0.0276716 |
| CRH | corticotropin releasing hormone | 0.027601 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0270722 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0269198 |
| EGR1 | early growth response 1 | 0.0262948 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0258273 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0255863 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0253533 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0253419 |
| FAM107B | family with sequence similarity 107, member B | 0.0248966 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0246819 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0243982 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0241194 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0236842 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0233292 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.0232424 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0231583 |
| ZNF804A | zinc finger protein 804A | 0.0229349 |
| VCAN | versican | 0.0227983 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0224495 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0220893 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0217816 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0217293 |
| PLSCR1 | phospholipid scramblase 1 | 0.0217124 |
| SMAD6 | SMAD family member 6 | 0.0216425 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.0215024 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0212982 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0212452 |
| PHF14 | PHD finger protein 14 | 0.0212149 |
| RAB7A | RAB7A, member RAS oncogene family | 0.021195 |
| FHIT | fragile histidine triad | 0.0211047 |
| CUX1 | cut-like homeobox 1 | 0.0209397 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0203992 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0203334 |
| FOXP1 | forkhead box P1 | 0.0203187 |
| FERMT2 | fermitin family member 2 | 0.0199063 |
| MCL1 | myeloid cell leukemia 1 | 0.0197774 |
| UBXN4 | UBX domain protein 4 | 0.01969 |
| BDKRB2 | bradykinin receptor B2 | 0.0196046 |
| OXR1 | oxidation resistance 1 | 0.0193384 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0192284 |
| SLFN5 | schlafen family member 5 | 0.0191167 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0190238 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0189244 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0189005 |
| DIAPH2 | diaphanous-related formin 2 | 0.0186353 |
| GAB2 | GRB2-associated binding protein 2 | 0.0185686 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0183653 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0182543 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.018089 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0180249 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0180191 |
| STXBP4 | syntaxin binding protein 4 | 0.0180131 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0178287 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0177165 |
| PRRX1 | paired related homeobox 1 | 0.0176939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.262589 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160631 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.104575 |
| VIM | vimentin | -0.0926047 |
| FAM13A | family with sequence similarity 13, member A | -0.0607562 |
| LPIN1 | lipin 1 | -0.0606239 |
| PTMA | prothymosin, alpha | -0.0493434 |
| HELZ | helicase with zinc finger | -0.0493401 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0483789 |
| DST | dystonin | -0.0440601 |
| RPL38 | ribosomal protein L38 | -0.0423986 |
| COL1A1 | collagen, type I, alpha 1 | -0.0405081 |
| FNBP1 | formin binding protein 1 | -0.0403458 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0400372 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.038646 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0374865 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0365062 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.036165 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0353548 |
| NEK7 | NIMA-related kinase 7 | -0.0350612 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0347977 |
| SETD5 | SET domain containing 5 | -0.0343899 |
| CLTC | clathrin, heavy chain (Hc) | -0.0338493 |
| ZNF292 | zinc finger protein 292 | -0.0332261 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0323599 |
| OGA | O-GlcNAcase | -0.0319699 |
| XPO1 | exportin 1 | -0.0316365 |
| WDR45B | WD repeat domain 45B | -0.0313178 |
| ADAR | adenosine deaminase, RNA-specific | -0.0309844 |
| FMN1 | formin 1 | -0.030582 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.030544 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0296802 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0296106 |
| SYT1 | synaptotagmin I | -0.0287075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0281599 |
| LMNA | lamin A/C | -0.0281069 |
| SBF2 | SET binding factor 2 | -0.0277357 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0273532 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0272298 |
| PLAT | plasminogen activator, tissue | -0.0264291 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0262478 |
| RPS6 | ribosomal protein S6 | -0.0260969 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0253658 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0247499 |
| SQSTM1 | sequestosome 1 | -0.0244935 |
| PKM | pyruvate kinase, muscle | -0.0243002 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0242318 |
| PTK2 | protein tyrosine kinase 2 | -0.0240806 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0240758 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0237004 |
| RPS2 | ribosomal protein S2 | -0.0235048 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0232731 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.023196 |
| NBAS | neuroblastoma amplified sequence | -0.0231252 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0230384 |
| BBX | bobby sox homolog (Drosophila) | -0.0229305 |
| CDC27 | cell division cycle 27 | -0.0228424 |
| ANXA2 | annexin A2 | -0.0225075 |
| H3-3B | H3.3 histone B | -0.0224807 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.021993 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0219657 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0217076 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0217042 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0216395 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.021608 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0213014 |
| MEIS2 | Meis homeobox 2 | -0.0212608 |
| PRTG | protogenin | -0.0211707 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0211143 |
| SLMAP | sarcolemma associated protein | -0.0210435 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.020966 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0206518 |
| SPAG9 | sperm associated antigen 9 | -0.0204061 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0203897 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0202408 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.020223 |
| CLINT1 | clathrin interactor 1 | -0.0200994 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0200284 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0199209 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0198759 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0197627 |
| UBC | ubiquitin C | -0.0197275 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0195594 |
| NF1 | neurofibromin 1 | -0.0195552 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0195477 |
| PAPOLA | poly(A) polymerase alpha | -0.0195235 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0192378 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0191341 |
| CASC3 | cancer susceptibility candidate 3 | -0.0190181 |
| FOXK2 | forkhead box K2 | -0.0189064 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0189011 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0188986 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0188791 |
| SRP54 | signal recognition particle 54kDa | -0.0188699 |
| RUNX1 | runt-related transcription factor 1 | -0.0187929 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0187561 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0186997 |
| EPHA3 | EPH receptor A3 | -0.0186312 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0185295 |
| COL3A1 | collagen, type III, alpha 1 | -0.018461 |
