| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.195896 |
| CADM1 | cell adhesion molecule 1 | 0.0565812 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444468 |
| VEGFA | vascular endothelial growth factor A | 0.0402337 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0401496 |
| RPL37A | ribosomal protein L37a | 0.0399417 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0385969 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0361071 |
| VMP1 | vacuole membrane protein 1 | 0.0351606 |
| GOLGB1 | golgin B1 | 0.0343542 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0323596 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0323543 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0318276 |
| SQSTM1 | sequestosome 1 | 0.0310306 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0308945 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0305472 |
| ADM | adrenomedullin | 0.0289924 |
| STC2 | stanniocalcin 2 | 0.0289778 |
| INTS6 | integrator complex subunit 6 | 0.0268325 |
| HM13 | histocompatibility (minor) 13 | 0.0247729 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0243324 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0238597 |
| RPS12 | ribosomal protein S12 | 0.0234581 |
| PGM3 | phosphoglucomutase 3 | 0.0230576 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0221078 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218886 |
| RPL31 | ribosomal protein L31 | 0.0215159 |
| HYOU1 | hypoxia up-regulated 1 | 0.0213915 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0212601 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0212406 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.021198 |
| CCNY | cyclin Y | 0.0211979 |
| RAB7A | RAB7A, member RAS oncogene family | 0.021006 |
| RCOR1 | REST corepressor 1 | 0.0209822 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0200905 |
| RPL35A | ribosomal protein L35a | 0.0200601 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.019824 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0191938 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0189884 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0189243 |
| MRTFA | myocardin related transcription factor A | 0.0187357 |
| CDK13 | cyclin-dependent kinase 13 | 0.0184729 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0181959 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0178758 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0178151 |
| RPS8 | ribosomal protein S8 | 0.017554 |
| GOLGA4 | golgin A4 | 0.0175223 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0173356 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0173031 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0171607 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0171468 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0170995 |
| NDRG1 | N-myc downstream regulated 1 | 0.0169103 |
| TMF1 | TATA element modulatory factor 1 | 0.0168205 |
| RPS25 | ribosomal protein S25 | 0.0165872 |
| SARS1 | seryl-tRNA synthetase 1 | 0.0165807 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0165199 |
| BRD2 | bromodomain containing 2 | 0.0163475 |
| HDAC9 | histone deacetylase 9 | 0.016159 |
| FNIP1 | folliculin interacting protein 1 | 0.0159978 |
| XYLT1 | xylosyltransferase I | 0.0158811 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0157313 |
| COPA | coatomer protein complex, subunit alpha | 0.0156069 |
| XPOT | exportin, tRNA | 0.0155126 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0155101 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0153172 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0152444 |
| COL5A1 | collagen, type V, alpha 1 | 0.0150661 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0150461 |
| ZNF644 | zinc finger protein 644 | 0.0149061 |
| RPS17 | ribosomal protein S17 | 0.014833 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0145053 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0144679 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0143665 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.014345 |
| NABP1 | nucleic acid binding protein 1 | 0.0143265 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.014237 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0142186 |
| GPHN | gephyrin | 0.0140604 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0140604 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0140213 |
| PLEC | plectin | 0.014021 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0139876 |
| RPL37 | ribosomal protein L37 | 0.0139747 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0139492 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0138982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0138452 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0138202 |
| RPS27A | ribosomal protein S27a | 0.0137243 |
| RTN3 | reticulon 3 | 0.0136122 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0134741 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0133943 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.01329 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0132343 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0131301 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0131186 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0130663 |
| TNS1 | tensin 1 | 0.0130539 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0130518 |
| FBXO11 | F-box protein 11 | 0.0128752 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.274892 |
| FN1 | fibronectin 1 | -0.248034 |
| MT2A | metallothionein 2A | -0.218552 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.19143 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175795 |
| COL1A1 | collagen, type I, alpha 1 | -0.146073 |
| TMSB10 | thymosin beta 10 | -0.110695 |
| COL6A3 | collagen, type VI, alpha 3 | -0.1072 |
| CD44 | CD44 molecule (Indian blood group) | -0.0846646 |
| MT1X | metallothionein 1X | -0.0834794 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0795223 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0778636 |
| COL1A2 | collagen, type I, alpha 2 | -0.074562 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0737409 |
| STC1 | stanniocalcin 1 | -0.0685495 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0672895 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0640843 |
| MAP1B | microtubule-associated protein 1B | -0.0622972 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0591847 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0555807 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0522555 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0505756 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0500851 |
| INHBA | inhibin, beta A | -0.0495047 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0493365 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0471071 |
| TMSB4X | thymosin beta 4, X-linked | -0.0452222 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0433744 |
| ATP13A3 | ATPase type 13A3 | -0.0430254 |
| EXT1 | exostosin glycosyltransferase 1 | -0.042731 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0421209 |
| RRBP1 | ribosome binding protein 1 | -0.0416644 |
| POSTN | periostin, osteoblast specific factor | -0.0412348 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0404388 |
| KLF6 | Kruppel-like factor 6 | -0.0403211 |
| PTK2 | protein tyrosine kinase 2 | -0.0396577 |
| TPM4 | tropomyosin 4 | -0.0395902 |
| VCAN | versican | -0.0376656 |
| CALR | calreticulin | -0.0375426 |
| ANXA2 | annexin A2 | -0.0374737 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0358681 |
| SMAD3 | SMAD family member 3 | -0.0358517 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0325101 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0321451 |
| RPL8 | ribosomal protein L8 | -0.0321352 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0320245 |
| TAGLN2 | transgelin 2 | -0.0312872 |
| AHNAK | AHNAK nucleoprotein | -0.0310152 |
| SBF2 | SET binding factor 2 | -0.030677 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0306445 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0301019 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0298459 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0292282 |
| ECE1 | endothelin converting enzyme 1 | -0.0291604 |
| ARRDC3 | arrestin domain containing 3 | -0.0290475 |
| SEPTIN7 | septin 7 | -0.0288416 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0288235 |
| IL6ST | interleukin 6 signal transducer | -0.0285641 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0284842 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0284162 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0282862 |
| S100A10 | S100 calcium binding protein A10 | -0.028179 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0281578 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.028146 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0280904 |
| H1-0 | H1.0 linker histone | -0.0278111 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.027722 |
| TPI1 | triosephosphate isomerase 1 | -0.0274561 |
| HAS2 | hyaluronan synthase 2 | -0.0273439 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0271362 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.026957 |
| OSMR | oncostatin M receptor | -0.0266188 |
| HMGA1 | high mobility group AT-hook 1 | -0.0265721 |
| PLAUR | plasminogen activator, urokinase receptor | -0.026557 |
| B2M | beta-2-microglobulin | -0.0264921 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0261169 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0261068 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0259632 |
| RPL18 | ribosomal protein L18 | -0.025775 |
| NRP1 | neuropilin 1 | -0.025681 |
| S100A9 | S100 calcium binding protein A9 | -0.0254545 |
| ASPH | aspartate beta-hydroxylase | -0.0252806 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0252267 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0250855 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0250613 |
| CALU | calumenin | -0.0250428 |
| PFN1 | profilin 1 | -0.0247195 |
| ANKRD12 | ankyrin repeat domain 12 | -0.024615 |
| PTMA | prothymosin, alpha | -0.0238197 |
| WASF2 | WAS protein family, member 2 | -0.0238097 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0237139 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0234276 |
| CANX | calnexin | -0.0234126 |
| HDLBP | high density lipoprotein binding protein | -0.0222443 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0217648 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0217485 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0217032 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0214885 |
| PGK1 | phosphoglycerate kinase 1 | -0.0214135 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0212939 |
