| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SVIL | supervillin | 0.0281118 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0237217 |
| TNS1 | tensin 1 | 0.0225692 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0225414 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0197858 |
| RPS12 | ribosomal protein S12 | 0.0194857 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.018987 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0178276 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0168414 |
| CRY1 | cryptochrome circadian clock 1 | 0.0166488 |
| RPL37A | ribosomal protein L37a | 0.0163613 |
| CAB39 | calcium binding protein 39 | 0.0161639 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0161457 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0158781 |
| SERINC1 | serine incorporator 1 | 0.0152291 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0151326 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0148407 |
| JMJD1C | jumonji domain containing 1C | 0.0145819 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0144825 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0141587 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0138842 |
| SET | SET nuclear proto-oncogene | 0.0131454 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0130718 |
| KALRN | kalirin, RhoGEF kinase | 0.0130508 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0129353 |
| CCNY | cyclin Y | 0.012823 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0123603 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.012272 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0122187 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0116363 |
| RPL30 | ribosomal protein L30 | 0.0115109 |
| RPL37 | ribosomal protein L37 | 0.0114828 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0113972 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0113907 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0113824 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0112747 |
| HM13 | histocompatibility (minor) 13 | 0.0112543 |
| GDI2 | GDP dissociation inhibitor 2 | 0.011187 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0111361 |
| RPS3 | ribosomal protein S3 | 0.0110579 |
| RPS7 | ribosomal protein S7 | 0.0109347 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0108775 |
| TCIM | transcriptional and immune response regulator | 0.0108759 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0106525 |
| FRK | fyn-related Src family tyrosine kinase | 0.0105822 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 | 0.0105375 |
| TFF1 | trefoil factor 1 | 0.0105227 |
| SEC24D | SEC24 family member D | 0.0103309 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0101055 |
| EFL1 | elongation factor like GTPase 1 | 0.0100617 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0100253 |
| RPS17 | ribosomal protein S17 | 0.0100112 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0100047 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.00999476 |
| RELL1 | RELT-like 1 | 0.00992504 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0099005 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00989598 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00983078 |
| SP3 | Sp3 transcription factor | 0.00979072 |
| RANBP9 | RAN binding protein 9 | 0.00976724 |
| SMAP1 | small ArfGAP 1 | 0.00967072 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.00961001 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00950362 |
| RPS27 | ribosomal protein S27 | 0.00945653 |
| PLAC8 | placenta-specific 8 | 0.00932388 |
| KRT19 | keratin 19, type I | 0.00920905 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.00918476 |
| RBP1 | retinol binding protein 1, cellular | 0.00909544 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00899104 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.00892757 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.00872657 |
| KIF5B | kinesin family member 5B | 0.0086728 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.00862141 |
| USP47 | ubiquitin specific peptidase 47 | 0.00861078 |
| TMF1 | TATA element modulatory factor 1 | 0.00856477 |
| S100A6 | S100 calcium binding protein A6 | 0.00846445 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0084205 |
| SLU7 | SLU7 splicing factor homolog (S. cerevisiae) | 0.00838459 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.00833408 |
| MORF4L2 | mortality factor 4 like 2 | 0.00830579 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.00829948 |
| AAK1 | AP2 associated kinase 1 | 0.00820848 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0081888 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0081591 |
| TMEM39A | transmembrane protein 39A | 0.0081381 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.00813233 |
| ITGA6 | integrin, alpha 6 | 0.00812755 |
| S100P | S100 calcium binding protein P | 0.00810191 |
| JAK1 | Janus kinase 1 | 0.00810104 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00807493 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00805833 |
| RPL31 | ribosomal protein L31 | 0.00804537 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00801743 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.00801461 |
| SLK | STE20-like kinase | 0.00793547 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.00791645 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.00790709 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00790626 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0078982 |
| TMEM87A | transmembrane protein 87A | 0.00788926 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.355688 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.31752 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.241591 |
| APOB | apolipoprotein B | -0.124686 |
| C3 | complement component 3 | -0.0963098 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0959892 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0897765 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0890391 |
| FN1 | fibronectin 1 | -0.0785462 |
| GPC6 | glypican 6 | -0.0697842 |
| APOA2 | apolipoprotein A-II | -0.0687416 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.067045 |
| GPC3 | glypican 3 | -0.0580837 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0566944 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0490679 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0473523 |
| EHBP1 | EH domain binding protein 1 | -0.0460855 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0459029 |
| MT2A | metallothionein 2A | -0.045535 |
| DST | dystonin | -0.043472 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0431746 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0431279 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0424449 |
| TRIM26 | tripartite motif containing 26 | -0.0416072 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0412339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0403845 |
| RPS6 | ribosomal protein S6 | -0.040173 |
| FTL | ferritin, light polypeptide | -0.0393352 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0392463 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384592 |
| FRMD5 | FERM domain containing 5 | -0.0369337 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0358659 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0349817 |
| TMEM123 | transmembrane protein 123 | -0.0348594 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.034198 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0331865 |
| GNAS | GNAS complex locus | -0.0329677 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0324724 |
| DOCK4 | dedicator of cytokinesis 4 | -0.032021 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0317642 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0305478 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.030305 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0297598 |
| APOE | apolipoprotein E | -0.0289686 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0287966 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0284262 |
| FMNL2 | formin-like 2 | -0.0282316 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0278439 |
| TF | transferrin | -0.0272523 |
| ACTN4 | actinin, alpha 4 | -0.0272188 |
| PEG3 | paternally expressed 3 | -0.0271593 |
| LYZ | lysozyme | -0.0266894 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0266464 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0262631 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0261792 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0261298 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0260013 |
| PTCHD4 | patched domain containing 4 | -0.025988 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0258263 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0254503 |
| A2M | alpha-2-macroglobulin | -0.0253518 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0253024 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0251877 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0249852 |
| HELZ | helicase with zinc finger | -0.0240269 |
| AHNAK | AHNAK nucleoprotein | -0.0236714 |
| PTMA | prothymosin, alpha | -0.0235908 |
| MSI2 | musashi RNA-binding protein 2 | -0.0235329 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0235126 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0234945 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0230821 |
| PKM | pyruvate kinase, muscle | -0.0228237 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0222735 |
| CMIP | c-Maf inducing protein | -0.0221867 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0220592 |
| DSPP | dentin sialophosphoprotein | -0.0219216 |
| RRBP1 | ribosome binding protein 1 | -0.0218583 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.021803 |
| RBM39 | RNA binding motif protein 39 | -0.0214428 |
| APOA1 | apolipoprotein A-I | -0.0214198 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0212749 |
| SFTPA2 | surfactant protein A2 | -0.0211908 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0210017 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0209992 |
| RPS5 | ribosomal protein S5 | -0.0209015 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0201643 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.020028 |
| KRT8 | keratin 8, type II | -0.0199744 |
| ATXN1 | ataxin 1 | -0.0197661 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0196925 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0195322 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0195277 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0195224 |
| IER3 | immediate early response 3 | -0.019487 |
| H1-0 | H1.0 linker histone | -0.0194431 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.019245 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0191963 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0189399 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0186656 |
| TRAM1 | translocation associated membrane protein 1 | -0.0186568 |
