| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.164639 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.134213 |
| LMO7 | LIM domain 7 | 0.0678002 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0605928 |
| RASAL2 | RAS protein activator like 2 | 0.0572607 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0560614 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0497657 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0469591 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0433645 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0416039 |
| B2M | beta-2-microglobulin | 0.0387021 |
| LDHA | lactate dehydrogenase A | 0.0367202 |
| CALB1 | calbindin 1, 28kDa | 0.0363879 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0362668 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0355603 |
| HMGA2 | high mobility group AT-hook 2 | 0.0334128 |
| TXNIP | thioredoxin interacting protein | 0.0328235 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0311248 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0304215 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294469 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0291071 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0290161 |
| HLA-E | major histocompatibility complex, class I, E | 0.028056 |
| HLA-B | major histocompatibility complex, class I, B | 0.0277131 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0267819 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0259063 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0258457 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.025519 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0251854 |
| AMOTL1 | angiomotin like 1 | 0.0239552 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0234321 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0234161 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0230001 |
| RNF217 | ring finger protein 217 | 0.0225899 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0224975 |
| IFI44L | interferon-induced protein 44-like | 0.0224519 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0221342 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.021976 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0218958 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0209921 |
| PODXL | podocalyxin-like | 0.0209671 |
| LAMC2 | laminin, gamma 2 | 0.0209186 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.020842 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0201381 |
| PLS3 | plastin 3 | 0.0198025 |
| HLA-A | major histocompatibility complex, class I, A | 0.0194566 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0192724 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0192328 |
| EGR1 | early growth response 1 | 0.0191066 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0191054 |
| PRSS23 | protease, serine, 23 | 0.0191015 |
| RPLP0 | ribosomal protein, large, P0 | 0.0186802 |
| FRMD4B | FERM domain containing 4B | 0.0177396 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 0.017696 |
| SQSTM1 | sequestosome 1 | 0.0175757 |
| TJP1 | tight junction protein 1 | 0.0175475 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0173055 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0172498 |
| RCOR1 | REST corepressor 1 | 0.0170853 |
| RPL35A | ribosomal protein L35a | 0.0161377 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0160083 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0157294 |
| S100A11 | S100 calcium binding protein A11 | 0.0153961 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0152812 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0149764 |
| UTRN | utrophin | 0.0147059 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0145712 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0145073 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0144855 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0144375 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0141163 |
| SIK3 | SIK family kinase 3 | 0.0139058 |
| RIGI | RNA sensor RIG-I | 0.0138772 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0137635 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0137462 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.013735 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0135001 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0133346 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0133191 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0131017 |
| MX2 | MX dynamin-like GTPase 2 | 0.0130674 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0129956 |
| DGKH | diacylglycerol kinase, eta | 0.0129819 |
| RPL37 | ribosomal protein L37 | 0.0129499 |
| MT1E | metallothionein 1E | 0.012823 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0127998 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | 0.0127645 |
| FTL | ferritin, light polypeptide | 0.0127358 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0126289 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0126216 |
| CSNK1E | casein kinase 1, epsilon | 0.0124141 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0124128 |
| POTEF | POTE ankyrin domain family, member F | 0.012411 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0122733 |
| TAGLN2 | transgelin 2 | 0.0119705 |
| PALLD | palladin, cytoskeletal associated protein | 0.0119631 |
| MTAP | methylthioadenosine phosphorylase | 0.0118555 |
| RPL27A | ribosomal protein L27a | 0.011852 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.011813 |
| RPL31 | ribosomal protein L31 | 0.0117348 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.136853 |
| CLU | clusterin | -0.105974 |
| FLNB | filamin B, beta | -0.0920325 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0813196 |
| CUL4B | cullin 4B | -0.0764576 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0663836 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0609194 |
| RBM39 | RNA binding motif protein 39 | -0.0596714 |
| MYOF | myoferlin | -0.0594189 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0582654 |
| KIAA1217 | KIAA1217 | -0.0568821 |
| GOLGA4 | golgin A4 | -0.0553162 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0552031 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0548713 |
| ANLN | anillin, actin binding protein | -0.0542386 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0539783 |
| MEF2A | myocyte enhancer factor 2A | -0.0525366 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0518366 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.050063 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0497676 |
| OGA | O-GlcNAcase | -0.0488387 |
| PRELID2 | PRELI domain containing 2 | -0.0450811 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0440831 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0432388 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0417444 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0411604 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0403075 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0399297 |
| SMAD3 | SMAD family member 3 | -0.0399086 |
| CANX | calnexin | -0.0370081 |
| LMNA | lamin A/C | -0.0368409 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0345603 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0341164 |
| BCL2L1 | BCL2-like 1 | -0.0339926 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0338386 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0334092 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0333295 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0331797 |
| AHNAK | AHNAK nucleoprotein | -0.0328739 |
| METTL15 | methyltransferase like 15 | -0.0322298 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0321981 |
| FOXO1 | forkhead box O1 | -0.0320046 |
| PLAT | plasminogen activator, tissue | -0.0319383 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0312477 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.031162 |
| RIN2 | Ras and Rab interactor 2 | -0.0311281 |
| EMP1 | epithelial membrane protein 1 | -0.0307989 |
| RPS6 | ribosomal protein S6 | -0.0301564 |
| COG5 | component of oligomeric golgi complex 5 | -0.0300296 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0300131 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0295941 |
| TMSB4X | thymosin beta 4, X-linked | -0.0293619 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0291728 |
| DSTN | destrin (actin depolymerizing factor) | -0.0288984 |
| TPX2 | TPX2, microtubule-associated | -0.0288906 |
| KIF16B | kinesin family member 16B | -0.028852 |
| PLEC | plectin | -0.0286133 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0285405 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0284881 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0278749 |
| MTSS1 | metastasis suppressor 1 | -0.0278703 |
| H1-0 | H1.0 linker histone | -0.027844 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0278302 |
| ITGA6 | integrin, alpha 6 | -0.0278223 |
| ARRDC3 | arrestin domain containing 3 | -0.0275815 |
| SUCO | SUN domain containing ossification factor | -0.0275501 |
| RPS2 | ribosomal protein S2 | -0.0271705 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.026946 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0266318 |
| PTMA | prothymosin, alpha | -0.0265555 |
| PDLIM1 | PDZ and LIM domain 1 | -0.0265087 |
| LDLR | low density lipoprotein receptor | -0.02597 |
| HM13 | histocompatibility (minor) 13 | -0.0259054 |
| RPS21 | ribosomal protein S21 | -0.0257321 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0256414 |
| SPAG9 | sperm associated antigen 9 | -0.0256088 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0255161 |
| KRT17 | keratin 17, type I | -0.0254671 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0254585 |
| IGF2 | insulin-like growth factor 2 | -0.0254448 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.024863 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0248618 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0248311 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246748 |
| GNAS | GNAS complex locus | -0.0242824 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0239117 |
| YBX3 | Y box binding protein 3 | -0.0238933 |
| XPO1 | exportin 1 | -0.0236542 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0236418 |
| MYO10 | myosin X | -0.0234505 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0234335 |
| SBF2 | SET binding factor 2 | -0.0231085 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0229977 |
| COPA | coatomer protein complex, subunit alpha | -0.0229052 |
| ZNF292 | zinc finger protein 292 | -0.0228603 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0226991 |
| CLTC | clathrin, heavy chain (Hc) | -0.022499 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0223135 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0222904 |
| EFHD2 | EF-hand domain family, member D2 | -0.0220582 |
