| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0538566 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0521106 |
| LMO7 | LIM domain 7 | 0.0490327 |
| RNF145 | ring finger protein 145 | 0.0387452 |
| RNF43 | ring finger protein 43 | 0.036749 |
| CENPF | centromere protein F, 350/400kDa | 0.0333453 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0328517 |
| FAT1 | FAT atypical cadherin 1 | 0.0327375 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0321031 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.027196 |
| MED13L | mediator complex subunit 13-like | 0.0265737 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0256871 |
| TNS4 | tensin 4 | 0.025294 |
| PTEN | phosphatase and tensin homolog | 0.0249807 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0247564 |
| PCDHB16 | protocadherin beta 16 | 0.0243328 |
| PCBP2 | poly(rC) binding protein 2 | 0.0236418 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0233896 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.022745 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0222514 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0222308 |
| MED13 | mediator complex subunit 13 | 0.0220153 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0218651 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0214899 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0213345 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0212682 |
| NUP58 | nucleoporin 58 | 0.0211087 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.020778 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.020132 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0201026 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.019906 |
| ETNK1 | ethanolamine kinase 1 | 0.0197512 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0196041 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0194297 |
| TXNRD1 | thioredoxin reductase 1 | 0.0194165 |
| WDR43 | WD repeat domain 43 | 0.0189514 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0189062 |
| TPM3 | tropomyosin 3 | 0.0188906 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0187719 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0186159 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0179191 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0177769 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0175538 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0175082 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0174737 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | 0.017238 |
| ERBIN | erbb2 interacting protein | 0.0170156 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0168983 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.016835 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0167682 |
| RBM25 | RNA binding motif protein 25 | 0.0163901 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0160112 |
| SLK | STE20-like kinase | 0.0159832 |
| POTEF | POTE ankyrin domain family, member F | 0.0159529 |
| GDA | guanine deaminase | 0.0159028 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0158872 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0158407 |
| HMGA1 | high mobility group AT-hook 1 | 0.0157526 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0156984 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0154662 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0153968 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.015341 |
| SERINC5 | serine incorporator 5 | 0.0153378 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0151643 |
| PNN | pinin, desmosome associated protein | 0.0151049 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0149693 |
| GOLGA4 | golgin A4 | 0.0148683 |
| PCM1 | pericentriolar material 1 | 0.0147966 |
| USP6NL | USP6 N-terminal like | 0.0146977 |
| PRRC2C | proline-rich coiled-coil 2C | 0.014635 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0145722 |
| VEGFA | vascular endothelial growth factor A | 0.014528 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0144541 |
| PLS1 | plastin 1 | 0.0144057 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0144018 |
| USP3 | ubiquitin specific peptidase 3 | 0.0143758 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0143686 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0143383 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.014226 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0142061 |
| SON | SON DNA binding protein | 0.0141348 |
| GPHN | gephyrin | 0.0141042 |
| RFX7 | regulatory factor X, 7 | 0.0140506 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0139716 |
| INSIG1 | insulin induced gene 1 | 0.0138979 |
| YTHDC1 | YTH domain containing 1 | 0.0138517 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0138274 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0137689 |
| SNX13 | sorting nexin 13 | 0.0137058 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0135376 |
| CENPE | centromere protein E, 312kDa | 0.0135208 |
| ATP11B | ATPase, class VI, type 11B | 0.0134522 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0134242 |
| ZNF148 | zinc finger protein 148 | 0.0133217 |
| YBX1 | Y box binding protein 1 | 0.0131868 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0131729 |
| YAP1 | Yes-associated protein 1 | 0.0131337 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0131267 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0130833 |
| CLDN7 | claudin 7 | 0.0130088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.227437 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.177818 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.173894 |
| NPSR1 | neuropeptide S receptor 1 | -0.166375 |
| PTMA | prothymosin, alpha | -0.147075 |
| MYO1E | myosin IE | -0.129373 |
| VCL | vinculin | -0.120082 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0988702 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0912575 |
| TMSB10 | thymosin beta 10 | -0.087319 |
| AHNAK | AHNAK nucleoprotein | -0.0828805 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0818611 |
| ONECUT3 | one cut homeobox 3 | -0.0795523 |
| TPM4 | tropomyosin 4 | -0.0769454 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0691279 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0689446 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0677317 |
| ACTG1 | actin gamma 1 | -0.0664273 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0653716 |
| RPS6 | ribosomal protein S6 | -0.0634447 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0605151 |
| PIGR | polymeric immunoglobulin receptor | -0.0602031 |
| RPL34 | ribosomal protein L34 | -0.0545775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0521655 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0505905 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0483746 |
| LAMA4 | laminin, alpha 4 | -0.0478235 |
| FHIT | fragile histidine triad | -0.0468654 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0456213 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.045544 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0452962 |
| RPS8 | ribosomal protein S8 | -0.0451828 |
| NDRG1 | N-myc downstream regulated 1 | -0.0449033 |
| PARD3 | par-3 family cell polarity regulator | -0.0444539 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0440346 |
| ANXA2 | annexin A2 | -0.0438526 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0434353 |
| PALLD | palladin, cytoskeletal associated protein | -0.0416646 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0410798 |
| RPL35A | ribosomal protein L35a | -0.040951 |
| FLNB | filamin B, beta | -0.0406618 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.039912 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0392725 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0391363 |
| DIAPH2 | diaphanous-related formin 2 | -0.0386352 |
| IER3 | immediate early response 3 | -0.0384198 |
| RPLP1 | ribosomal protein, large, P1 | -0.0377479 |
| KLF6 | Kruppel-like factor 6 | -0.0374253 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0373159 |
| S100A6 | S100 calcium binding protein A6 | -0.0372943 |
| NEBL | nebulette | -0.0366321 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.036247 |
| FHL2 | four and a half LIM domains 2 | -0.0361516 |
| AGR2 | anterior gradient 2 | -0.0361128 |
| RIGI | RNA sensor RIG-I | -0.0356771 |
| FBXO11 | F-box protein 11 | -0.0354571 |
| RPS24 | ribosomal protein S24 | -0.0352994 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0351502 |
| RPS27A | ribosomal protein S27a | -0.0350339 |
| USP53 | ubiquitin specific peptidase 53 | -0.0347788 |
| ACTN4 | actinin, alpha 4 | -0.0345578 |
| TFF1 | trefoil factor 1 | -0.0344952 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0343032 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0342259 |
| RPL26 | ribosomal protein L26 | -0.0341817 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0338434 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0336341 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0334188 |
| RPS25 | ribosomal protein S25 | -0.032151 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0320762 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0318319 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0316244 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0315218 |
| S100A10 | S100 calcium binding protein A10 | -0.0314907 |
| SMYD3 | SET and MYND domain containing 3 | -0.0309475 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.030925 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0309205 |
| DENND1A | DENN/MADD domain containing 1A | -0.0307879 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0304579 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0303066 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302865 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301588 |
| RPL31 | ribosomal protein L31 | -0.0300369 |
| RPL9 | ribosomal protein L9 | -0.0297776 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0297293 |
| MT2A | metallothionein 2A | -0.0296835 |
| RPL37A | ribosomal protein L37a | -0.0289874 |
| PCDH9 | protocadherin 9 | -0.0288165 |
| EGFR | epidermal growth factor receptor | -0.0288111 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0287442 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0286366 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0284318 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0278074 |
| CUX1 | cut-like homeobox 1 | -0.0274835 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0273198 |
| KRT8 | keratin 8, type II | -0.0273127 |
| ATXN1 | ataxin 1 | -0.0272679 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272246 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0270898 |
