| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0988229 |
| DST | dystonin | 0.0575981 |
| TXNIP | thioredoxin interacting protein | 0.0479407 |
| CANX | calnexin | 0.0427285 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0388087 |
| ENO1 | enolase 1, (alpha) | 0.031902 |
| PTMA | prothymosin, alpha | 0.0317155 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0305644 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.029857 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0297843 |
| SPAG9 | sperm associated antigen 9 | 0.02972 |
| EZR | ezrin | 0.0270388 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0263945 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0262199 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0256378 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0249489 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0248926 |
| CEP350 | centrosomal protein 350kDa | 0.0246295 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0245258 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0244868 |
| GOLGA4 | golgin A4 | 0.0241059 |
| XPO1 | exportin 1 | 0.0236642 |
| PGK1 | phosphoglycerate kinase 1 | 0.0233825 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.022859 |
| SLK | STE20-like kinase | 0.0224712 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0218073 |
| CDK13 | cyclin-dependent kinase 13 | 0.0211998 |
| RPLP1 | ribosomal protein, large, P1 | 0.0210701 |
| ITSN2 | intersectin 2 | 0.0207846 |
| CALR | calreticulin | 0.0204357 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0203712 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.019631 |
| KLHL24 | kelch-like family member 24 | 0.0195379 |
| TPM4 | tropomyosin 4 | 0.0194218 |
| PCM1 | pericentriolar material 1 | 0.0194184 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0185639 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0183483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0178224 |
| RPS6 | ribosomal protein S6 | 0.0172435 |
| RPS29 | ribosomal protein S29 | 0.0172172 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0170608 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0169165 |
| VMP1 | vacuole membrane protein 1 | 0.0168922 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0162679 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0161523 |
| KIF5B | kinesin family member 5B | 0.0161247 |
| F2R | coagulation factor II (thrombin) receptor | 0.0160832 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0160545 |
| SEPTIN7 | septin 7 | 0.0156121 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0155858 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0153748 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.015262 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0149936 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.014887 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0147735 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0147365 |
| PDS5A | PDS5 cohesin associated factor A | 0.0146878 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.0146752 |
| OPTN | optineurin | 0.0146572 |
| SRP54 | signal recognition particle 54kDa | 0.0145456 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0143185 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0142471 |
| SUCO | SUN domain containing ossification factor | 0.0141567 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0141221 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.014069 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0140673 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0140115 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.0140028 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0139966 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0139949 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0139931 |
| SEC24D | SEC24 family member D | 0.0139225 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0138396 |
| GOLGB1 | golgin B1 | 0.0138091 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0136381 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0135619 |
| RPL38 | ribosomal protein L38 | 0.0134564 |
| RPS23 | ribosomal protein S23 | 0.0134312 |
| VCL | vinculin | 0.0133863 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0133201 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0132811 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0132084 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0131986 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0131722 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0130926 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0128791 |
| RPL37A | ribosomal protein L37a | 0.0128608 |
| HLA-A | major histocompatibility complex, class I, A | 0.0128593 |
| SETD5 | SET domain containing 5 | 0.0128287 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0127534 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0127302 |
| CALU | calumenin | 0.0126105 |
| MATR3 | matrin 3 | 0.0125263 |
| USP47 | ubiquitin specific peptidase 47 | 0.0125178 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0124883 |
| HLA-E | major histocompatibility complex, class I, E | 0.0123621 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0123541 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0122096 |
| LYST | lysosomal trafficking regulator | 0.0120472 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0118647 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.19014 |
| VIM | vimentin | -0.125813 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.12296 |
| TMSB10 | thymosin beta 10 | -0.0900861 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0818851 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0683025 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0678721 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0632419 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0553322 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0543232 |
| SLC38A2 | solute carrier family 38, member 2 | -0.052872 |
| MT1X | metallothionein 1X | -0.0528705 |
| CD44 | CD44 molecule (Indian blood group) | -0.0512844 |
| TXNRD1 | thioredoxin reductase 1 | -0.051166 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0438465 |
| RAI1 | retinoic acid induced 1 | -0.0430474 |
| EHBP1 | EH domain binding protein 1 | -0.0427033 |
| TMSB4X | thymosin beta 4, X-linked | -0.0395452 |
| EGR1 | early growth response 1 | -0.0375548 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0360628 |
| RPLP0 | ribosomal protein, large, P0 | -0.0359553 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0357882 |
| HMGA1 | high mobility group AT-hook 1 | -0.0352285 |
| CMIP | c-Maf inducing protein | -0.0349883 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0349682 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0347472 |
| DNER | delta/notch-like EGF repeat containing | -0.0345294 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034495 |
| KLF6 | Kruppel-like factor 6 | -0.0332508 |
| RPL12 | ribosomal protein L12 | -0.0322521 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0314713 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0308103 |
| MT1E | metallothionein 1E | -0.0304837 |
| PTK2 | protein tyrosine kinase 2 | -0.0304497 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0303826 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0302634 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299215 |
| RPS3 | ribosomal protein S3 | -0.0299051 |
| RPL26 | ribosomal protein L26 | -0.0294408 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294038 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0291691 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.028923 |
| STK17A | serine/threonine kinase 17a | -0.0287326 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0284673 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.028301 |
| DENND1A | DENN/MADD domain containing 1A | -0.0281387 |
| S100A6 | S100 calcium binding protein A6 | -0.0278412 |
| APP | amyloid beta (A4) precursor protein | -0.0273628 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.027169 |
| RUNX1 | runt-related transcription factor 1 | -0.0268125 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0264487 |
| RPL18 | ribosomal protein L18 | -0.026371 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0261597 |
| NEK10 | NIMA-related kinase 10 | -0.0258403 |
| FMNL2 | formin-like 2 | -0.0254458 |
| RPL23 | ribosomal protein L23 | -0.0251916 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0251681 |
| PODXL | podocalyxin-like | -0.0248162 |
| RPL19 | ribosomal protein L19 | -0.0247426 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0243087 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0237831 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0233899 |
| FLNB | filamin B, beta | -0.0233284 |
| RPS4X | ribosomal protein S4, X-linked | -0.023197 |
| RBM25 | RNA binding motif protein 25 | -0.0227535 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0225348 |
| TSC22D1 | TSC22 domain family, member 1 | -0.022396 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.022177 |
| EREG | epiregulin | -0.0219291 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0219273 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0217685 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.021653 |
| PDE10A | phosphodiesterase 10A | -0.0215944 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0215932 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0209352 |
| TP63 | tumor protein p63 | -0.0209242 |
| ACTG1 | actin gamma 1 | -0.0206051 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0202948 |
| OSMR | oncostatin M receptor | -0.0200918 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0197277 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0192901 |
| AHNAK | AHNAK nucleoprotein | -0.0190867 |
| FBXO11 | F-box protein 11 | -0.01899 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0187549 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0183865 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0181845 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0180919 |
| PLSCR1 | phospholipid scramblase 1 | -0.017964 |
| TPI1 | triosephosphate isomerase 1 | -0.0178203 |
| ANGPTL4 | angiopoietin-like 4 | -0.0176263 |
| WDR27 | WD repeat domain 27 | -0.0174315 |
| RASAL2 | RAS protein activator like 2 | -0.0172401 |
| COMMD10 | COMM domain containing 10 | -0.0171172 |
| KRT18 | keratin 18, type I | -0.0170706 |
| BMERB1 | bMERB domain containing 1 | -0.0169983 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0169144 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0167198 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0164021 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0162374 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0161981 |
