| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.123518 |
| GLCCI1 | glucocorticoid induced 1 | 0.104059 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0896963 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0787562 |
| PCBP2 | poly(rC) binding protein 2 | 0.0724987 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0630115 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0624116 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0623866 |
| VMP1 | vacuole membrane protein 1 | 0.0618182 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0585905 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0551282 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0548133 |
| NTN4 | netrin 4 | 0.0545429 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0488973 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0427199 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0407049 |
| SMAD3 | SMAD family member 3 | 0.0396212 |
| SQSTM1 | sequestosome 1 | 0.0396106 |
| KYNU | kynureninase | 0.0381564 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0380945 |
| ADD3 | adducin 3 (gamma) | 0.0374829 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0366435 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0358681 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0352366 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0345199 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0343123 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0341032 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.032632 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0324993 |
| NRP1 | neuropilin 1 | 0.0324571 |
| AHR | aryl hydrocarbon receptor | 0.0322154 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0312395 |
| FNDC3B | fibronectin type III domain containing 3B | 0.030807 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.030653 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0300415 |
| KSR1 | kinase suppressor of ras 1 | 0.0294757 |
| NAV2 | neuron navigator 2 | 0.0294367 |
| DUSP16 | dual specificity phosphatase 16 | 0.0292419 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0292187 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0291654 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0290252 |
| MED13 | mediator complex subunit 13 | 0.0287843 |
| INTS6 | integrator complex subunit 6 | 0.0286597 |
| ERBIN | erbb2 interacting protein | 0.0286499 |
| RPS6 | ribosomal protein S6 | 0.0280407 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0278633 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0276768 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0276282 |
| PALLD | palladin, cytoskeletal associated protein | 0.0271448 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0264276 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0261103 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0260855 |
| ZNF638 | zinc finger protein 638 | 0.025975 |
| OPTN | optineurin | 0.0257102 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0255575 |
| CD44 | CD44 molecule (Indian blood group) | 0.0250865 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0243461 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0239705 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0237375 |
| RNF145 | ring finger protein 145 | 0.0236528 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0235041 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0234948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0234528 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0234202 |
| PRSS3 | protease, serine, 3 | 0.0233159 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.023286 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231665 |
| YME1L1 | YME1-like 1 ATPase | 0.023165 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0230813 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0229352 |
| LOX | lysyl oxidase | 0.0226532 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.022555 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0225349 |
| STK38L | serine/threonine kinase 38 like | 0.021459 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.021221 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0210195 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0210176 |
| RIOK3 | RIO kinase 3 | 0.0204342 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0201732 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0201205 |
| ARSJ | arylsulfatase family, member J | 0.0201015 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0200854 |
| UTRN | utrophin | 0.0199091 |
| RARB | retinoic acid receptor, beta | 0.0197806 |
| TGM2 | transglutaminase 2 | 0.019774 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0197265 |
| GPHN | gephyrin | 0.0197151 |
| RAB10 | RAB10, member RAS oncogene family | 0.0196866 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0196654 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0194546 |
| NABP1 | nucleic acid binding protein 1 | 0.0193816 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0191829 |
| EVI5 | ecotropic viral integration site 5 | 0.0191588 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0191392 |
| AVIL | advillin | 0.0191326 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0189771 |
| XPO1 | exportin 1 | 0.0186445 |
| CLTC | clathrin, heavy chain (Hc) | 0.0186194 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0185561 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0184311 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.267658 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.20844 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.19796 |
| TMSB10 | thymosin beta 10 | -0.170055 |
| CDH13 | cadherin 13 | -0.149545 |
| FN1 | fibronectin 1 | -0.106101 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.102587 |
| GPC6 | glypican 6 | -0.0984544 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0942602 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0905389 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0899587 |
| NDRG1 | N-myc downstream regulated 1 | -0.0851394 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0818528 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0810484 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0809387 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0798972 |
| FTL | ferritin, light polypeptide | -0.0764638 |
| NRG1 | neuregulin 1 | -0.0732255 |
| STC1 | stanniocalcin 1 | -0.0662887 |
| OSMR | oncostatin M receptor | -0.0650509 |
| MT2A | metallothionein 2A | -0.0620687 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0614364 |
| FAM20C | family with sequence similarity 20, member C | -0.0605638 |
| MTSS1 | metastasis suppressor 1 | -0.0595432 |
| OXR1 | oxidation resistance 1 | -0.0589343 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0586286 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0579727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0563452 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0549588 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0545408 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0526991 |
| MEF2A | myocyte enhancer factor 2A | -0.0522107 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0516567 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0514091 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0513905 |
| S100A6 | S100 calcium binding protein A6 | -0.0506447 |
| EGR1 | early growth response 1 | -0.0477569 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0475294 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0470664 |
| TNNC1 | troponin C type 1 (slow) | -0.0460664 |
| CFAP20DC | CFAP20 domain containing | -0.0446409 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0446165 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0435612 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0435482 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0426653 |
| USP34 | ubiquitin specific peptidase 34 | -0.0421717 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0421026 |
| NAV1 | neuron navigator 1 | -0.0405386 |
| ZNF804A | zinc finger protein 804A | -0.0403197 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0402835 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0389702 |
| DIAPH2 | diaphanous-related formin 2 | -0.0389074 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0385958 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0384081 |
| MX2 | MX dynamin-like GTPase 2 | -0.0378352 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.037581 |
| IER3 | immediate early response 3 | -0.0370575 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0369491 |
| ATG7 | autophagy related 7 | -0.0368793 |
| RNF213 | ring finger protein 213 | -0.0360417 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0358725 |
| B2M | beta-2-microglobulin | -0.0354823 |
| DTNA | dystrobrevin, alpha | -0.0352552 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0346941 |
| CDK14 | cyclin-dependent kinase 14 | -0.0346787 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0342725 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.033854 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0338111 |
| GLIS3 | GLIS family zinc finger 3 | -0.03377 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.033577 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.033408 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0325829 |
| MCL1 | myeloid cell leukemia 1 | -0.0325244 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0305653 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0301028 |
| HDAC4 | histone deacetylase 4 | -0.0300887 |
| DNER | delta/notch-like EGF repeat containing | -0.0299889 |
| PYGL | phosphorylase, glycogen, liver | -0.0299055 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0296128 |
| CLMP | CXADR-like membrane protein | -0.0295636 |
| CUX1 | cut-like homeobox 1 | -0.0291936 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0290859 |
| NAV3 | neuron navigator 3 | -0.0290652 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0290278 |
| SUMF1 | sulfatase modifying factor 1 | -0.0287941 |
| SYNJ2 | synaptojanin 2 | -0.0276107 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.027592 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0275267 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0273955 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0273214 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0273143 |
| RPL36 | ribosomal protein L36 | -0.0272592 |
| PRELID2 | PRELI domain containing 2 | -0.0271655 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0267555 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0265159 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0260716 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0258759 |
| PTMA | prothymosin, alpha | -0.0255579 |
| ENOSF1 | enolase superfamily member 1 | -0.0255267 |
| PRSS23 | protease, serine, 23 | -0.0253151 |
