| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.107601 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0930264 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0871503 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0833736 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0741574 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0628991 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0622221 |
| MT2A | metallothionein 2A | 0.0608692 |
| SPAG9 | sperm associated antigen 9 | 0.0581199 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0560907 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0507016 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0504336 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0496571 |
| FAM13A | family with sequence similarity 13, member A | 0.0489785 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0482733 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0470293 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0448987 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433215 |
| HELZ | helicase with zinc finger | 0.0429117 |
| FUS | FUS RNA binding protein | 0.0428659 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0417088 |
| SRPK2 | SRSF protein kinase 2 | 0.0413139 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0410628 |
| STAG2 | stromal antigen 2 | 0.0402489 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0398864 |
| UBE3C | ubiquitin protein ligase E3C | 0.0398272 |
| UBN2 | ubinuclein 2 | 0.0395626 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0392051 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.038862 |
| SMYD3 | SET and MYND domain containing 3 | 0.0381019 |
| SMAD3 | SMAD family member 3 | 0.0376344 |
| RYBP | RING1 and YY1 binding protein | 0.0370812 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0370355 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0366314 |
| ATP13A3 | ATPase type 13A3 | 0.0366133 |
| MED13 | mediator complex subunit 13 | 0.0365783 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0362102 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0358759 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0358259 |
| NKTR | natural killer cell triggering receptor | 0.0356422 |
| HDLBP | high density lipoprotein binding protein | 0.0354597 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0350133 |
| SEC24A | SEC24 family member A | 0.0347754 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0347493 |
| RNF24 | ring finger protein 24 | 0.0337535 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0335428 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0331731 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0330488 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0329264 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0327457 |
| COLEC11 | collectin sub-family member 11 | 0.0327157 |
| CERT1 | ceramide transporter 1 | 0.0326731 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0325177 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0323657 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0322211 |
| RPS3 | ribosomal protein S3 | 0.0321521 |
| TSC22D1 | TSC22 domain family, member 1 | 0.031638 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0315603 |
| TMEM165 | transmembrane protein 165 | 0.0313877 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0310587 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0309272 |
| OGA | O-GlcNAcase | 0.0308129 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0307524 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0305816 |
| ANO6 | anoctamin 6 | 0.0305193 |
| ARFGEF3 | ARFGEF family member 3 | 0.0304495 |
| TUFT1 | tuftelin 1 | 0.0304059 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0303843 |
| CALU | calumenin | 0.030261 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0301336 |
| FRYL | FRY-like | 0.0301006 |
| XPO1 | exportin 1 | 0.0299683 |
| SDC4 | syndecan 4 | 0.0299146 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0298649 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0296818 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0293563 |
| B2M | beta-2-microglobulin | 0.0292899 |
| LAMC2 | laminin, gamma 2 | 0.0291663 |
| ENO1 | enolase 1, (alpha) | 0.0290845 |
| CANX | calnexin | 0.0286881 |
| GOLGA4 | golgin A4 | 0.0284586 |
| FOXO3 | forkhead box O3 | 0.0283032 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0282714 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0281576 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0279374 |
| ATP11B | ATPase, class VI, type 11B | 0.0279279 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277258 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0276576 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0275681 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0274332 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0272413 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0270811 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0270719 |
| PTK2 | protein tyrosine kinase 2 | 0.0268 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0267437 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0267326 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0265673 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0265554 |
| RUNX1 | runt-related transcription factor 1 | 0.0263715 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0260154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.146206 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0992245 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0977973 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0830735 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0809006 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0761669 |
| THBS1 | thrombospondin 1 | -0.066207 |
| EFNA5 | ephrin-A5 | -0.0653002 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0638026 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0634516 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0606711 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0585745 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0569749 |
| MYOF | myoferlin | -0.0545852 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0544271 |
| S100A9 | S100 calcium binding protein A9 | -0.0526491 |
| RAI14 | retinoic acid induced 14 | -0.0522699 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0487025 |
| ABHD17C | abhydrolase domain containing 17C | -0.0484458 |
| SIK3 | SIK family kinase 3 | -0.048045 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0480384 |
| S100A8 | S100 calcium binding protein A8 | -0.0461826 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0458543 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.045515 |
| RIOK3 | RIO kinase 3 | -0.0451134 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0450796 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0448832 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0445334 |
| QKI | QKI, KH domain containing, RNA binding | -0.0444471 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0437732 |
| H3-3B | H3.3 histone B | -0.0436945 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0427251 |
| DST | dystonin | -0.042111 |
| EZR | ezrin | -0.0418713 |
| JMJD1C | jumonji domain containing 1C | -0.0416893 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0413306 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0395758 |
| KIF13B | kinesin family member 13B | -0.0393678 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0389983 |
| ASPH | aspartate beta-hydroxylase | -0.038424 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0381864 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0381629 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0379571 |
| GPC6 | glypican 6 | -0.037644 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0375776 |
| EGR1 | early growth response 1 | -0.0371332 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0369759 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0369335 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0367749 |
| GOLGB1 | golgin B1 | -0.0362235 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0358879 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0356335 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0355807 |
| FTL | ferritin, light polypeptide | -0.0351312 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0351138 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0349527 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0348849 |
| TXNRD1 | thioredoxin reductase 1 | -0.0347434 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0347416 |
| RBM47 | RNA binding motif protein 47 | -0.0344995 |
| ATOSA | atos homolog A | -0.0344342 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0340155 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0339681 |
| TLK1 | tousled-like kinase 1 | -0.033636 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0335598 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0335516 |
| CADM2 | cell adhesion molecule 2 | -0.032914 |
| BPTF | bromodomain PHD finger transcription factor | -0.0327909 |
| TNPO1 | transportin 1 | -0.0327566 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0321036 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.032074 |
| HMGA2 | high mobility group AT-hook 2 | -0.0319695 |
| CDC27 | cell division cycle 27 | -0.0319579 |
| ATXN2 | ataxin 2 | -0.0315429 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0315106 |
| AHNAK | AHNAK nucleoprotein | -0.0314059 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0313107 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0312083 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0311 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0309835 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0308633 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.03076 |
| CMIP | c-Maf inducing protein | -0.0306219 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0303969 |
| DIDO1 | death inducer-obliterator 1 | -0.0303427 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0300664 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0300303 |
| ETV6 | ets variant 6 | -0.0300262 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.0300165 |
| TUSC3 | tumor suppressor candidate 3 | -0.0295698 |
| NEK7 | NIMA-related kinase 7 | -0.0295418 |
| FLNB | filamin B, beta | -0.0293902 |
| SNX14 | sorting nexin 14 | -0.0293269 |
| ANXA2 | annexin A2 | -0.0290402 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0289488 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0288077 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0287669 |
| RNF213 | ring finger protein 213 | -0.0284167 |
| MUC16 | mucin 16, cell surface associated | -0.0284125 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0282529 |
