| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0960023 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0651795 |
| PDLIM5 | PDZ and LIM domain 5 | 0.061979 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0553281 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0429463 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0349555 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0324379 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0320377 |
| IL6 | interleukin 6 | 0.0308026 |
| CHL1 | cell adhesion molecule L1-like | 0.0289996 |
| RPS12 | ribosomal protein S12 | 0.0282221 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0271633 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0271013 |
| LSAMP | limbic system-associated membrane protein | 0.0264512 |
| MCL1 | myeloid cell leukemia 1 | 0.0248495 |
| EGR1 | early growth response 1 | 0.02473 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0246546 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0236345 |
| MT2A | metallothionein 2A | 0.0231821 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.023062 |
| MAP7 | microtubule-associated protein 7 | 0.0228227 |
| CD109 | CD109 molecule | 0.0218413 |
| POTEF | POTE ankyrin domain family, member F | 0.0217673 |
| NTN4 | netrin 4 | 0.0216416 |
| FMNL2 | formin-like 2 | 0.0214401 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.020794 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0207761 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0195943 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.019289 |
| RPS2 | ribosomal protein S2 | 0.0187615 |
| TENM2 | teneurin transmembrane protein 2 | 0.0181691 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0170294 |
| ESM1 | endothelial cell-specific molecule 1 | 0.0165976 |
| FAM107B | family with sequence similarity 107, member B | 0.0163462 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0160259 |
| VMP1 | vacuole membrane protein 1 | 0.0159239 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0158543 |
| TXNIP | thioredoxin interacting protein | 0.0157977 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0154314 |
| BMP6 | bone morphogenetic protein 6 | 0.0153887 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.015383 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0150497 |
| DNER | delta/notch-like EGF repeat containing | 0.0149892 |
| PCBP2 | poly(rC) binding protein 2 | 0.0148563 |
| XYLT1 | xylosyltransferase I | 0.0146868 |
| AUTS2 | autism susceptibility candidate 2 | 0.0143388 |
| AXL | AXL receptor tyrosine kinase | 0.0140933 |
| ASTN2 | astrotactin 2 | 0.0140835 |
| PCDH9 | protocadherin 9 | 0.0138509 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0135453 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0135164 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0135056 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0134546 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0130415 |
| RPS7 | ribosomal protein S7 | 0.0130263 |
| RPL3 | ribosomal protein L3 | 0.0129674 |
| MYADM | myeloid-associated differentiation marker | 0.0129124 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0128272 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0128117 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.012689 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.012605 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0124798 |
| SLK | STE20-like kinase | 0.0123167 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0120552 |
| RPL39 | ribosomal protein L39 | 0.0119907 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0119851 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0118282 |
| SVIL | supervillin | 0.0117514 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0116019 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0115957 |
| RPS27 | ribosomal protein S27 | 0.0114173 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0114138 |
| PGM2L1 | phosphoglucomutase 2-like 1 | 0.0114117 |
| OLFML2A | olfactomedin-like 2A | 0.0113412 |
| TENM3 | teneurin transmembrane protein 3 | 0.0111339 |
| GLRX | glutaredoxin (thioltransferase) | 0.0110745 |
| ITGB8 | integrin, beta 8 | 0.0110158 |
| SCARA5 | scavenger receptor class A, member 5 | 0.0109314 |
| NRXN3 | neurexin 3 | 0.0108494 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0108441 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0107092 |
| NBEAL1 | neurobeachin-like 1 | 0.0103684 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0103505 |
| MT1X | metallothionein 1X | 0.0103457 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0102534 |
| IL6R | interleukin 6 receptor | 0.0101062 |
| HMGA2 | high mobility group AT-hook 2 | 0.0100816 |
| RPLP0 | ribosomal protein, large, P0 | 0.0100693 |
| MSN | moesin | 0.0100686 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0100549 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.010029 |
| LAMA5 | laminin, alpha 5 | 0.010022 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00984075 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00981676 |
| RHCG | Rh family, C glycoprotein | 0.00979041 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.00962256 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00955993 |
| TOB1 | transducer of ERBB2, 1 | 0.00955638 |
| DUSP4 | dual specificity phosphatase 4 | 0.0095039 |
| ZFP36 | ZFP36 ring finger protein | 0.00947861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.209213 |
| ASPH | aspartate beta-hydroxylase | -0.135149 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.134315 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.129771 |
| EFNA5 | ephrin-A5 | -0.111208 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106628 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104913 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.101277 |
| TXNRD1 | thioredoxin reductase 1 | -0.0981219 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0916266 |
| PTMA | prothymosin, alpha | -0.0871279 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0863626 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.085 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0838562 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0823212 |
| VIM | vimentin | -0.0815241 |
| TMSB10 | thymosin beta 10 | -0.0809622 |
| SMYD3 | SET and MYND domain containing 3 | -0.0774153 |
| PDE10A | phosphodiesterase 10A | -0.0749182 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0734399 |
| NRCAM | neuronal cell adhesion molecule | -0.0733351 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0705814 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0703057 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0684951 |
| OGA | O-GlcNAcase | -0.0607811 |
| RPS24 | ribosomal protein S24 | -0.0602412 |
| RBM39 | RNA binding motif protein 39 | -0.0585037 |
| GNAS | GNAS complex locus | -0.0569591 |
| MYOF | myoferlin | -0.0524643 |
| PCBP3 | poly(rC) binding protein 3 | -0.0511239 |
| ACTG1 | actin gamma 1 | -0.0510988 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0507913 |
| TNPO1 | transportin 1 | -0.0499236 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0498029 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0494194 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0490596 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.048468 |
| RTN4 | reticulon 4 | -0.0466191 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0464869 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0454786 |
| CANX | calnexin | -0.0441955 |
| VCL | vinculin | -0.0433852 |
| HLA-B | major histocompatibility complex, class I, B | -0.0422972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0401586 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0395345 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0388523 |
| RPL34 | ribosomal protein L34 | -0.0384406 |
| RPL38 | ribosomal protein L38 | -0.0380046 |
| RPL23 | ribosomal protein L23 | -0.0377618 |
| SPAG9 | sperm associated antigen 9 | -0.0377475 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.037453 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0372635 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0368672 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0366865 |
| FUS | FUS RNA binding protein | -0.0366599 |
| SRGN | serglycin | -0.0352243 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0345556 |
| NEK7 | NIMA-related kinase 7 | -0.0344289 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0343724 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0340062 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0337818 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0336985 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0336058 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0335225 |
| DST | dystonin | -0.0330349 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0326314 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0324655 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0319397 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0318763 |
| RPL35A | ribosomal protein L35a | -0.0317457 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0316052 |
| NF1 | neurofibromin 1 | -0.031395 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0312421 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0307598 |
| S100A10 | S100 calcium binding protein A10 | -0.0307159 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0305427 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.030487 |
| RRBP1 | ribosome binding protein 1 | -0.0303803 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0302987 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0302071 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0301072 |
| ENAH | enabled homolog (Drosophila) | -0.0296884 |
| MORF4L2 | mortality factor 4 like 2 | -0.0296727 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0294745 |
| PTGR1 | prostaglandin reductase 1 | -0.0293851 |
| RPS21 | ribosomal protein S21 | -0.0293581 |
| GOLGA4 | golgin A4 | -0.0291918 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0291586 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0291133 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0287825 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0287417 |
| GRAMD1B | GRAM domain containing 1B | -0.028678 |
| RPS6 | ribosomal protein S6 | -0.0284452 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0284066 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0282552 |
| AHNAK | AHNAK nucleoprotein | -0.0282289 |
| ARF1 | ADP-ribosylation factor 1 | -0.027753 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0276155 |
| PGK1 | phosphoglycerate kinase 1 | -0.0273249 |
| NOP58 | NOP58 ribonucleoprotein | -0.0269281 |
