| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.051298 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0396543 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0365647 |
| POTEF | POTE ankyrin domain family, member F | 0.0355445 |
| IL6 | interleukin 6 | 0.0317742 |
| FNIP1 | folliculin interacting protein 1 | 0.0311347 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0305848 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0290156 |
| INTS6 | integrator complex subunit 6 | 0.0285986 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0282266 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0269799 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.026772 |
| RND3 | Rho family GTPase 3 | 0.0265835 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0261589 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0260858 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0256414 |
| TPM3 | tropomyosin 3 | 0.0243178 |
| MAGT1 | magnesium transporter 1 | 0.0241724 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0241577 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0238156 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0233614 |
| ITM2B | integral membrane protein 2B | 0.0232141 |
| RPS8 | ribosomal protein S8 | 0.0229993 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0229258 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0227653 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.022545 |
| UBE3C | ubiquitin protein ligase E3C | 0.0222453 |
| WTAP | Wilms tumor 1 associated protein | 0.0221706 |
| CDH13 | cadherin 13 | 0.0220501 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0220405 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0212247 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0207472 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0198087 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0197869 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0195686 |
| EGFR | epidermal growth factor receptor | 0.0189613 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0187696 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | 0.0185065 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0180547 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.018036 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0179443 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0178894 |
| DMXL1 | Dmx-like 1 | 0.0178293 |
| SMAD4 | SMAD family member 4 | 0.0178089 |
| ITGAV | integrin, alpha V | 0.0177279 |
| NLN | neurolysin (metallopeptidase M3 family) | 0.017642 |
| MSN | moesin | 0.0176197 |
| ZYG11B | zyg-11 family member B, cell cycle regulator | 0.0174299 |
| PGM3 | phosphoglucomutase 3 | 0.017416 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0173219 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0172864 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0171983 |
| SEPTIN2 | septin 2 | 0.0171951 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.0171389 |
| HYOU1 | hypoxia up-regulated 1 | 0.0167742 |
| AUTS2 | autism susceptibility candidate 2 | 0.0167108 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0166899 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0166747 |
| NUP58 | nucleoporin 58 | 0.0164893 |
| CCDC138 | coiled-coil domain containing 138 | 0.0164424 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0163701 |
| L1CAM | L1 cell adhesion molecule | 0.0163636 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 0.016267 |
| HDLBP | high density lipoprotein binding protein | 0.0160896 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0158116 |
| LIMA1 | LIM domain and actin binding 1 | 0.0158017 |
| UBAP2 | ubiquitin associated protein 2 | 0.0157427 |
| HELZ | helicase with zinc finger | 0.0156966 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.0156937 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0156919 |
| LAMB3 | laminin, beta 3 | 0.0156777 |
| NRDC | nardilysin convertase | 0.0156739 |
| ANAPC10 | anaphase promoting complex subunit 10 | 0.015669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.015648 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0156046 |
| RPL9 | ribosomal protein L9 | 0.0155673 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.0155618 |
| NABP1 | nucleic acid binding protein 1 | 0.0155585 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa | 0.0155299 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.015517 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0155149 |
| FAM193B | family with sequence similarity 193, member B | 0.0153683 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0152994 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0152209 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0150819 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.015008 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0149722 |
| SUCO | SUN domain containing ossification factor | 0.0147795 |
| GDI2 | GDP dissociation inhibitor 2 | 0.014766 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0147252 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0146987 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0146562 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0146539 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.0146118 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0144988 |
| ZNF638 | zinc finger protein 638 | 0.0144927 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0144856 |
| TBCA | tubulin folding cofactor A | 0.0144712 |
| YY1AP1 | YY1 associated protein 1 | 0.0144558 |
| COG6 | component of oligomeric golgi complex 6 | 0.0143993 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.26001 |
| MT2A | metallothionein 2A | -0.180608 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.162539 |
| TMSB10 | thymosin beta 10 | -0.155255 |
| VIM | vimentin | -0.14953 |
| COL1A1 | collagen, type I, alpha 1 | -0.133647 |
| FN1 | fibronectin 1 | -0.128998 |
| CALU | calumenin | -0.0932065 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0823654 |
| COL1A2 | collagen, type I, alpha 2 | -0.0782938 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0736211 |
| AHNAK | AHNAK nucleoprotein | -0.0730805 |
| HLA-B | major histocompatibility complex, class I, B | -0.0714069 |
| CD44 | CD44 molecule (Indian blood group) | -0.0674219 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0671629 |
| NDRG1 | N-myc downstream regulated 1 | -0.064253 |
| LOX | lysyl oxidase | -0.0633696 |
| KAZN | kazrin, periplakin interacting protein | -0.0617905 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0612319 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0610891 |
| HIP1 | huntingtin interacting protein 1 | -0.0608089 |
| ANXA2 | annexin A2 | -0.0591539 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0571205 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0549646 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0514265 |
| MT1X | metallothionein 1X | -0.0506526 |
| ENO1 | enolase 1, (alpha) | -0.0498175 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.048989 |
| PGK1 | phosphoglycerate kinase 1 | -0.048715 |
| PRSS23 | protease, serine, 23 | -0.0484064 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0475017 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0461371 |
| GLIS3 | GLIS family zinc finger 3 | -0.0457674 |
| CALD1 | caldesmon 1 | -0.0454742 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0439844 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.043487 |
| RRBP1 | ribosome binding protein 1 | -0.0432139 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0421056 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0419294 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0417754 |
| TPM4 | tropomyosin 4 | -0.040697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0390544 |
| CAVIN1 | caveolae associated protein 1 | -0.0389427 |
| PTK2 | protein tyrosine kinase 2 | -0.038618 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0380587 |
| GLG1 | golgi glycoprotein 1 | -0.0375931 |
| ADM | adrenomedullin | -0.0371928 |
| MAP1B | microtubule-associated protein 1B | -0.0369401 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0369239 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0355507 |
| ARRDC3 | arrestin domain containing 3 | -0.0353556 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.034646 |
| HLA-C | major histocompatibility complex, class I, C | -0.0343799 |
| PTMA | prothymosin, alpha | -0.0336788 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0336134 |
| TPM1 | tropomyosin 1 (alpha) | -0.0331257 |
| CDK6 | cyclin-dependent kinase 6 | -0.0331166 |
| FAM13A | family with sequence similarity 13, member A | -0.0328639 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0328119 |
| GNAS | GNAS complex locus | -0.0327631 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0326367 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0325424 |
| RAB31 | RAB31, member RAS oncogene family | -0.032522 |
| CADM1 | cell adhesion molecule 1 | -0.0317438 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0317123 |
| LOXL2 | lysyl oxidase-like 2 | -0.0308483 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0307302 |
| ECE1 | endothelin converting enzyme 1 | -0.0296371 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.029352 |
| RAB27A | RAB27A, member RAS oncogene family | -0.0289844 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0287039 |
| CALR | calreticulin | -0.0287027 |
| RTN4 | reticulon 4 | -0.0286097 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0282507 |
| HPCAL1 | hippocalcin-like 1 | -0.0282164 |
| COL3A1 | collagen, type III, alpha 1 | -0.0280204 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0280042 |
| RAI14 | retinoic acid induced 14 | -0.0278616 |
| CANX | calnexin | -0.0276725 |
| STK10 | serine/threonine kinase 10 | -0.0274837 |
| NRXN3 | neurexin 3 | -0.0274641 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0270656 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.026835 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0264687 |
| GSE1 | Gse1 coiled-coil protein | -0.0264333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0260252 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0258704 |
| TXNIP | thioredoxin interacting protein | -0.0256893 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0255833 |
| RLF | rearranged L-myc fusion | -0.0255696 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0251925 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251229 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0247856 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0246674 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0245639 |
| CD99 | CD99 molecule | -0.0244129 |
| CBX3 | chromobox homolog 3 | -0.0243297 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0242528 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0240346 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0239785 |
