| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ritonavir perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ritonavir_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0685354 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0593006 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.058897 |
| SMAD3 | SMAD family member 3 | 0.0494111 |
| VMP1 | vacuole membrane protein 1 | 0.045067 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0388909 |
| JMJD1C | jumonji domain containing 1C | 0.0385223 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0345662 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344314 |
| ITSN2 | intersectin 2 | 0.0333074 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0331453 |
| RIGI | RNA sensor RIG-I | 0.0313695 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0286867 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0281823 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0272962 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.027204 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0265129 |
| ITGB4 | integrin, beta 4 | 0.0264777 |
| NAV2 | neuron navigator 2 | 0.0262613 |
| SET | SET nuclear proto-oncogene | 0.0258189 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0256715 |
| RAI1 | retinoic acid induced 1 | 0.025323 |
| NKTR | natural killer cell triggering receptor | 0.0247553 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0247431 |
| EGR1 | early growth response 1 | 0.0247421 |
| AREG | amphiregulin | 0.0246426 |
| TMEM245 | transmembrane protein 245 | 0.0246022 |
| MSN | moesin | 0.0245825 |
| SVIL | supervillin | 0.0238936 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0238087 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0229113 |
| ANXA1 | annexin A1 | 0.022901 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0228916 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0228292 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0223735 |
| DIAPH1 | diaphanous-related formin 1 | 0.0219193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0218186 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0214226 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0207512 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0206315 |
| SMC5 | structural maintenance of chromosomes 5 | 0.020553 |
| NGLY1 | N-glycanase 1 | 0.0205348 |
| CCNL1 | cyclin L1 | 0.0204709 |
| FAM3C | family with sequence similarity 3, member C | 0.0200301 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.01999 |
| MYOF | myoferlin | 0.01982 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0195154 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.01948 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0191407 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0191179 |
| MIS18BP1 | MIS18 binding protein 1 | 0.018886 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0188039 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0186184 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0184442 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0184211 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0183336 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0183136 |
| CAPRIN2 | caprin family member 2 | 0.0182083 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0181695 |
| MB21D2 | Mab-21 domain containing 2 | 0.0180564 |
| STK24 | serine/threonine kinase 24 | 0.0179677 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0179636 |
| ITGB5 | integrin, beta 5 | 0.0179365 |
| VEGFA | vascular endothelial growth factor A | 0.0179107 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.01781 |
| ANO6 | anoctamin 6 | 0.0176346 |
| ITGAV | integrin, alpha V | 0.0176013 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0175433 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0174943 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0174703 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0174681 |
| NDRG1 | N-myc downstream regulated 1 | 0.0173989 |
| CCDC88A | coiled-coil domain containing 88A | 0.0173833 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0171204 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0170525 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0168804 |
| PDE10A | phosphodiesterase 10A | 0.0168579 |
| RPL36 | ribosomal protein L36 | 0.0166796 |
| SMAD2 | SMAD family member 2 | 0.0166573 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.016537 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0163789 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0162645 |
| EGFR | epidermal growth factor receptor | 0.0162532 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0161156 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0160491 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0159803 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0159082 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0158508 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0158036 |
| ATP13A3 | ATPase type 13A3 | 0.0157889 |
| HDAC9 | histone deacetylase 9 | 0.0156031 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0154215 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0153627 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.015314 |
| KRIT1 | KRIT1, ankyrin repeat containing | 0.0150681 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.015063 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0149437 |
| YTHDC1 | YTH domain containing 1 | 0.0148927 |
| CCNT2 | cyclin T2 | 0.0147962 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0147337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.382868 |
| VIM | vimentin | -0.224212 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.140202 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0970492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.070813 |
| TMSB10 | thymosin beta 10 | -0.0695185 |
| HMGA2 | high mobility group AT-hook 2 | -0.0560282 |
| GNAS | GNAS complex locus | -0.0544182 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0526642 |
| IGF2 | insulin-like growth factor 2 | -0.0515699 |
| MAP1B | microtubule-associated protein 1B | -0.0507769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0494165 |
| FUS | FUS RNA binding protein | -0.047207 |
| ATM | ATM serine/threonine kinase | -0.0465965 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0445511 |
| INTS6 | integrator complex subunit 6 | -0.0442678 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0437949 |
| CD44 | CD44 molecule (Indian blood group) | -0.0430677 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.04187 |
| OSMR | oncostatin M receptor | -0.0413404 |
| ACTG1 | actin gamma 1 | -0.0404298 |
| CANX | calnexin | -0.0392428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0380809 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0378595 |
| AHNAK | AHNAK nucleoprotein | -0.0377189 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.03758 |
| SMYD3 | SET and MYND domain containing 3 | -0.0373769 |
| UBC | ubiquitin C | -0.0350993 |
| H3-3B | H3.3 histone B | -0.0346702 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0343378 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0340535 |
| RPS13 | ribosomal protein S13 | -0.0340053 |
| FMN1 | formin 1 | -0.0338996 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0330281 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0310272 |
| DEK | DEK proto-oncogene | -0.0307795 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0306931 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0303483 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0299498 |
| RRBP1 | ribosome binding protein 1 | -0.0299387 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0298424 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0297086 |
| RBM39 | RNA binding motif protein 39 | -0.0286338 |
| MED13L | mediator complex subunit 13-like | -0.028097 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0280653 |
| RPL26 | ribosomal protein L26 | -0.027906 |
| PHF3 | PHD finger protein 3 | -0.0277924 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0277004 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0275292 |
| PDCD6IP | programmed cell death 6 interacting protein | -0.0272723 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0272497 |
| S100A10 | S100 calcium binding protein A10 | -0.0270031 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0267771 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0266696 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0265376 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0263215 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.026296 |
| RPS8 | ribosomal protein S8 | -0.0260485 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0259286 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0257613 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0253775 |
| SDC4 | syndecan 4 | -0.0252706 |
| HMGA1 | high mobility group AT-hook 1 | -0.0252546 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0249619 |
| PKM | pyruvate kinase, muscle | -0.0249157 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0247744 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0246366 |
| AEBP2 | AE binding protein 2 | -0.0244352 |
| RBMX | RNA binding motif protein, X-linked | -0.0242531 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0240607 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.02397 |
| TCF12 | transcription factor 12 | -0.0239466 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0239282 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0238304 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0236937 |
| PHF21A | PHD finger protein 21A | -0.0236575 |
| PTMA | prothymosin, alpha | -0.0236567 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0234361 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0233346 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0231378 |
| RANBP17 | RAN binding protein 17 | -0.0231141 |
| GSK3B | glycogen synthase kinase 3 beta | -0.023082 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0229303 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0228108 |
| SEPTIN7 | septin 7 | -0.0225007 |
| RPS27A | ribosomal protein S27a | -0.0223251 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0222569 |
| CALU | calumenin | -0.0222151 |
| PYGL | phosphorylase, glycogen, liver | -0.022152 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0216975 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0215513 |
| BBX | bobby sox homolog (Drosophila) | -0.0214722 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0214104 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0213387 |
| SEPTIN9 | septin 9 | -0.0211297 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0209195 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0208426 |
| PRELID2 | PRELI domain containing 2 | -0.0207283 |
| ATG7 | autophagy related 7 | -0.0206869 |
| POTEF | POTE ankyrin domain family, member F | -0.0206075 |
