| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/77991 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Rivastigmine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP44 | Rho GTPase activating protein 44 | 2.11 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 1.22 |
| NPHP3 | nephronophthisis 3 (adolescent) | 1.19 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 1.17 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.78 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.78 |
| TEX15 | testis expressed 15 | 0.73 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.73 |
| SPTA1 | spectrin, alpha, erythrocytic 1 | 0.72 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 0.69 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.68 |
| CGNL1 | cingulin-like 1 | 0.64 |
| PROSER3 | proline and serine rich 3 | 0.61 |
| CLSPN | claspin | 0.59 |
| BORA | bora, aurora kinase A activator | 0.58 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | 0.56 |
| KSR2 | kinase suppressor of ras 2 | 0.56 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.56 |
| BCOR | BCL6 corepressor | 0.55 |
| FANCF | Fanconi anemia, complementation group F | 0.54 |
| CCDC112 | coiled-coil domain containing 112 | 0.54 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.54 |
| TMEM64 | transmembrane protein 64 | 0.52 |
| CFAP57 | cilia and flagella associated protein 57 | 0.51 |
| DOCK3 | dedicator of cytokinesis 3 | 0.51 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.47 |
| MANEAL | mannosidase, endo-alpha-like | 0.46 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.44 |
| TFR2 | transferrin receptor 2 | 0.43 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.43 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.42 |
| NKD2 | naked cuticle homolog 2 (Drosophila) | 0.42 |
| BMP4 | bone morphogenetic protein 4 | 0.42 |
| MYPOP | Myb-related transcription factor, partner of profilin | 0.4 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | 0.4 |
| C17ORF53 | chromosome 17 open reading frame 53 | 0.4 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.39 |
| REEP1 | receptor accessory protein 1 | 0.39 |
| MAGEA2 | melanoma antigen family A2 | 0.39 |
| ALS2CL | ALS2 C-terminal like | 0.39 |
| ATXN1L | ataxin 1-like | 0.38 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.38 |
| CMC4 | C-x(9)-C motif containing 4 | 0.38 |
| DNM1 | dynamin 1 | 0.38 |
| ZNF865 | zinc finger protein 865 | 0.37 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 | 0.37 |
| ZIC2 | Zic family member 2 | 0.37 |
| MPZL2 | myelin protein zero-like 2 | 0.36 |
| MSX1 | msh homeobox 1 | 0.36 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.36 |
| RPS19BP1 | ribosomal protein S19 binding protein 1 | 0.35 |
| RASSF7 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 | 0.35 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.35 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.34 |
| TMEM160 | transmembrane protein 160 | 0.34 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.34 |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.33 |
| B2M | beta-2-microglobulin | 0.33 |
| HSPA14 | heat shock 70kDa protein 14 | 0.33 |
| OGG1 | 8-oxoguanine DNA glycosylase | 0.33 |
| HMBOX1 | homeobox containing 1 | 0.33 |
| OTX1 | orthodenticle homeobox 1 | 0.33 |
| ASB3 | ankyrin repeat and SOCS box containing 3 | 0.33 |
| ARSK | arylsulfatase family, member K | 0.33 |
| ZNF124 | zinc finger protein 124 | 0.32 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.32 |
| H3C1 | H3 clustered histone 1 | 0.32 |
| AMMECR1L | AMMECR1-like | 0.32 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.31 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | 0.31 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | 0.31 |
| DENND3 | DENN/MADD domain containing 3 | 0.31 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.3 |
| ZNF749 | zinc finger protein 749 | 0.3 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.3 |
| MRPS18C | mitochondrial ribosomal protein S18C | 0.3 |
| CASKIN1 | CASK interacting protein 1 | 0.3 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.29 |
| MITD1 | MIT, microtubule interacting and transport, domain containing 1 | 0.29 |
| TYRO3 | TYRO3 protein tyrosine kinase | 0.29 |
| PTMA | prothymosin, alpha | 0.29 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.29 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.29 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 0.28 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.28 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 | 0.28 |
| RBMXL3 | RNA binding motif protein, X-linked-like 3 | 0.28 |
| FASTK | Fas-activated serine/threonine kinase | 0.28 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.28 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.28 |
| RNF17 | ring finger protein 17 | 0.27 |
| GPATCH2L | G patch domain containing 2-like | 0.27 |
| PRELID1 | PRELI domain containing 1 | 0.27 |
| IRF2 | interferon regulatory factor 2 | 0.27 |
| ZDHHC12 | zinc finger, DHHC-type containing 12 | 0.27 |
| CAB39L | calcium binding protein 39-like | 0.26 |
| C20ORF27 | chromosome 20 open reading frame 27 | 0.26 |
| GPN2 | GPN-loop GTPase 2 | 0.26 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 0.26 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.77 |
| NIN | ninein (GSK3B interacting protein) | -0.77 |
| ZNF436 | zinc finger protein 436 | -0.76 |
| MRFAP1 | Morf4 family associated protein 1 | -0.75 |
| BOK | BCL2-related ovarian killer | -0.72 |
| GCH1 | GTP cyclohydrolase 1 | -0.58 |
| SERAC1 | serine active site containing 1 | -0.57 |
| MYO9A | myosin IXA | -0.56 |
| S100A2 | S100 calcium binding protein A2 | -0.56 |
| CD58 | CD58 molecule | -0.51 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.51 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.5 |
| SZT2 | seizure threshold 2 homolog (mouse) | -0.48 |
| UNC80 | unc-80 homolog (C. elegans) | -0.47 |
| ZFPM1 | zinc finger protein, FOG family member 1 | -0.46 |
| LYST | lysosomal trafficking regulator | -0.45 |
| LYRM1 | LYR motif containing 1 | -0.45 |
| CD82 | CD82 molecule | -0.45 |
| AKIRIN2 | akirin 2 | -0.44 |
| PRR36 | proline rich 36 | -0.42 |
| CLIC3 | chloride intracellular channel 3 | -0.4 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.4 |
| STK17A | serine/threonine kinase 17a | -0.4 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | -0.4 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.39 |
| MT-ND4 | NADH dehydrogenase, subunit 4 (complex I) | -0.39 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.39 |
| PML | promyelocytic leukemia | -0.38 |
| GALT | galactose-1-phosphate uridylyltransferase | -0.38 |
| FAM122A | family with sequence similarity 122A | -0.37 |
| INPP5J | inositol polyphosphate-5-phosphatase J | -0.37 |
| BCORL1 | BCL6 corepressor-like 1 | -0.37 |
| ARSD | arylsulfatase D | -0.37 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | -0.37 |
| TMEM179B | transmembrane protein 179B | -0.37 |
| PGK2 | phosphoglycerate kinase 2 | -0.37 |
| CCNI | cyclin I | -0.36 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | -0.36 |
| C1ORF50 | chromosome 1 open reading frame 50 | -0.36 |
| FAM104A | family with sequence similarity 104, member A | -0.36 |
| CCS | copper chaperone for superoxide dismutase | -0.35 |
| S100A11 | S100 calcium binding protein A11 | -0.35 |
| PTK6 | protein tyrosine kinase 6 | -0.35 |
| USP19 | ubiquitin specific peptidase 19 | -0.35 |
| FAM221A | family with sequence similarity 221, member A | -0.34 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -0.34 |
| S100A14 | S100 calcium binding protein A14 | -0.34 |
| TSKU | tsukushi, small leucine rich proteoglycan | -0.34 |
| PEX19 | peroxisomal biogenesis factor 19 | -0.34 |
| PSEN1 | presenilin 1 | -0.34 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.34 |
| DPY30 | dpy-30 homolog (C. elegans) | -0.33 |
| DOLPP1 | dolichyldiphosphatase 1 | -0.33 |
| TBC1D32 | TBC1 domain family, member 32 | -0.33 |
| MED31 | mediator complex subunit 31 | -0.33 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 | -0.33 |
| TPCN1 | two pore segment channel 1 | -0.32 |
| SUCO | SUN domain containing ossification factor | -0.32 |
| SLX4IP | SLX4 interacting protein | -0.32 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.32 |
| COX19 | COX19 cytochrome c oxidase assembly factor | -0.32 |
| KCTD21 | potassium channel tetramerization domain containing 21 | -0.32 |
| PHF1 | PHD finger protein 1 | -0.31 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.31 |
| HRH1 | histamine receptor H1 | -0.31 |
| NUCB2 | nucleobindin 2 | -0.31 |
| NLGN2 | neuroligin 2 | -0.31 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -0.31 |
| FTL | ferritin, light polypeptide | -0.31 |
| KLHL20 | kelch-like family member 20 | -0.31 |
| ADIRF | adipogenesis regulatory factor | -0.31 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.31 |
| TTN | titin | -0.3 |
| CARD19 | caspase recruitment domain family member 19 | -0.3 |
| ADIPOR1 | adiponectin receptor 1 | -0.3 |
| NPHP1 | nephronophthisis 1 (juvenile) | -0.3 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | -0.3 |
| PROS1 | protein S (alpha) | -0.3 |
| PFDN1 | prefoldin subunit 1 | -0.3 |
| CEP63 | centrosomal protein 63kDa | -0.3 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.3 |
| SPATA2L | spermatogenesis associated 2-like | -0.29 |
| MCRIP1 | MAPK regulated corepressor interacting protein 1 | -0.29 |
| RAB37 | RAB37, member RAS oncogene family | -0.29 |
| RNF185 | ring finger protein 185 | -0.29 |
| AMDHD1 | amidohydrolase domain containing 1 | -0.29 |
| TMSB10 | thymosin beta 10 | -0.29 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.29 |
| MED29 | mediator complex subunit 29 | -0.29 |
| PPP1R14C | protein phosphatase 1, regulatory (inhibitor) subunit 14C | -0.29 |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 | -0.29 |
| PCDH1 | protocadherin 1 | -0.29 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | -0.28 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.28 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.28 |
| NAGS | N-acetylglutamate synthase | -0.28 |
| ABHD3 | abhydrolase domain containing 3 | -0.28 |
| NIPA2 | non imprinted in Prader-Willi/Angelman syndrome 2 | -0.28 |
| DEAF1 | DEAF1 transcription factor | -0.28 |
| PFDN6 | prefoldin subunit 6 | -0.28 |
