| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.114457 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.112087 |
| UBC | ubiquitin C | 0.0928212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0803108 |
| AHNAK | AHNAK nucleoprotein | 0.0785195 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0745031 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0738984 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.073011 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0696382 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0684448 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0666798 |
| JAK1 | Janus kinase 1 | 0.0652402 |
| SMAD3 | SMAD family member 3 | 0.0623603 |
| PDLIM5 | PDZ and LIM domain 5 | 0.059523 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0593516 |
| APP | amyloid beta (A4) precursor protein | 0.0578575 |
| NAV2 | neuron navigator 2 | 0.0557144 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0540834 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0536713 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0524932 |
| SPAG9 | sperm associated antigen 9 | 0.0522246 |
| SEPTIN9 | septin 9 | 0.0511349 |
| INTS6 | integrator complex subunit 6 | 0.0497994 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0486082 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0483643 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0476456 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.047644 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0475529 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0470848 |
| CALU | calumenin | 0.0470363 |
| CTBP2 | C-terminal binding protein 2 | 0.0469191 |
| FLNA | filamin A, alpha | 0.0468757 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0441845 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0439446 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0438632 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0434545 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0430055 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0428896 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0428533 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0427498 |
| RHEB | Ras homolog enriched in brain | 0.0424182 |
| COG5 | component of oligomeric golgi complex 5 | 0.0422398 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0420354 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0420305 |
| PTK2 | protein tyrosine kinase 2 | 0.0410124 |
| VIM | vimentin | 0.0408694 |
| PLK2 | polo-like kinase 2 | 0.040855 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0406322 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0400227 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0395359 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0394216 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0388338 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0387788 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0383979 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0380433 |
| KYNU | kynureninase | 0.0377952 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0377002 |
| ATP13A3 | ATPase type 13A3 | 0.0365289 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0364819 |
| RPS27A | ribosomal protein S27a | 0.0361916 |
| CADM1 | cell adhesion molecule 1 | 0.0356404 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353934 |
| SUCO | SUN domain containing ossification factor | 0.0348993 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0348201 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0347067 |
| DENND4A | DENN/MADD domain containing 4A | 0.0343734 |
| RASA2 | RAS p21 protein activator 2 | 0.0343147 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0342239 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0341964 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0339295 |
| VCL | vinculin | 0.0339004 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0338089 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0332753 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0332107 |
| JUN | jun proto-oncogene | 0.0331195 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0328593 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0328429 |
| TUT7 | terminal uridylyl transferase 7 | 0.0325558 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0325324 |
| NUP98 | nucleoporin 98kDa | 0.0323505 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0323179 |
| HELZ | helicase with zinc finger | 0.0322463 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0320598 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0320571 |
| ANKRD17 | ankyrin repeat domain 17 | 0.032031 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0319959 |
| LDHA | lactate dehydrogenase A | 0.031882 |
| RANBP2 | RAN binding protein 2 | 0.0317356 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0316783 |
| TLN1 | talin 1 | 0.0314436 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0314248 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0313921 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0309768 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0304401 |
| OGA | O-GlcNAcase | 0.0303302 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0300971 |
| UBE3C | ubiquitin protein ligase E3C | 0.0300752 |
| DENND5A | DENN/MADD domain containing 5A | 0.0300731 |
| CDK13 | cyclin-dependent kinase 13 | 0.0299378 |
| PALLD | palladin, cytoskeletal associated protein | 0.0298603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.310225 |
| FRMD4A | FERM domain containing 4A | -0.120049 |
| GPC6 | glypican 6 | -0.110334 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0741306 |
| NDRG1 | N-myc downstream regulated 1 | -0.073228 |
| RPS6 | ribosomal protein S6 | -0.0676854 |
| HLA-B | major histocompatibility complex, class I, B | -0.0644484 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0565951 |
| CP | ceruloplasmin (ferroxidase) | -0.0563381 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0504028 |
| RRBP1 | ribosome binding protein 1 | -0.044211 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.040668 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397062 |
| B2M | beta-2-microglobulin | -0.0396067 |
| PLIN2 | perilipin 2 | -0.0377117 |
| RAI14 | retinoic acid induced 14 | -0.0373191 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0351643 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0347857 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0336704 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0325427 |
| PFN1 | profilin 1 | -0.0318095 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0315679 |
| GLIS3 | GLIS family zinc finger 3 | -0.0314684 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0310969 |
| RPL35A | ribosomal protein L35a | -0.0305498 |
| ANXA4 | annexin A4 | -0.0297124 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0293241 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0287596 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0270428 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0269601 |
| EXOC4 | exocyst complex component 4 | -0.0264068 |
| CTSD | cathepsin D | -0.0263523 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0257592 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0253984 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0247262 |
| TRIM56 | tripartite motif containing 56 | -0.0246423 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0238001 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0237009 |
| CBX3 | chromobox homolog 3 | -0.0233452 |
| CXXC1 | CXXC finger protein 1 | -0.0231422 |
| CUX1 | cut-like homeobox 1 | -0.022894 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0228248 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0224332 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0224064 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0221714 |
| BNC2 | basonuclin 2 | -0.0218348 |
| UBXN4 | UBX domain protein 4 | -0.0213854 |
| FRMD5 | FERM domain containing 5 | -0.0213259 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0210401 |
| PTGR1 | prostaglandin reductase 1 | -0.0208988 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0206343 |
| DIAPH3 | diaphanous-related formin 3 | -0.0202824 |
| NUCB2 | nucleobindin 2 | -0.0197787 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0193618 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0192907 |
| S100A11 | S100 calcium binding protein A11 | -0.0191561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0190801 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0190515 |
| HMGB1 | high mobility group box 1 | -0.0189443 |
| OXR1 | oxidation resistance 1 | -0.0188806 |
| DIAPH2 | diaphanous-related formin 2 | -0.0185077 |
| CLMP | CXADR-like membrane protein | -0.018488 |
| EFNA5 | ephrin-A5 | -0.0184844 |
| APOL1 | apolipoprotein L, 1 | -0.0183255 |
| TMSB10 | thymosin beta 10 | -0.0181028 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0180758 |
| PAX8 | paired box 8 | -0.0180315 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.017859 |
| RAD51B | RAD51 paralog B | -0.0178023 |
| FTL | ferritin, light polypeptide | -0.0178023 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0176438 |
| ANXA1 | annexin A1 | -0.0176363 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0174845 |
| TRAM1 | translocation associated membrane protein 1 | -0.0174072 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0172505 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.017232 |
| MTDH | metadherin | -0.016994 |
| CDK6 | cyclin-dependent kinase 6 | -0.016773 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.016698 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0166639 |
| ITM2B | integral membrane protein 2B | -0.0165271 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0164978 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0163608 |
| HLA-A | major histocompatibility complex, class I, A | -0.0163586 |
| TPM1 | tropomyosin 1 (alpha) | -0.0160685 |
| PTH2R | parathyroid hormone 2 receptor | -0.0159894 |
| EFHD2 | EF-hand domain family, member D2 | -0.0155601 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0155202 |
| VEGFA | vascular endothelial growth factor A | -0.0154756 |
| MAP4 | microtubule-associated protein 4 | -0.0153106 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0153082 |
| HLA-C | major histocompatibility complex, class I, C | -0.015262 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.015218 |
| FAM13A | family with sequence similarity 13, member A | -0.0151693 |
| PHF14 | PHD finger protein 14 | -0.0151429 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0150545 |
| RPL36A | ribosomal protein L36a | -0.0149069 |
| IKBIP | IKBKB interacting protein | -0.014881 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0147818 |
| IFI44L | interferon-induced protein 44-like | -0.0147354 |
