| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.247515 |
| GPC6 | glypican 6 | 0.186194 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.130167 |
| UBC | ubiquitin C | 0.105455 |
| ASPH | aspartate beta-hydroxylase | 0.085135 |
| ZYX | zyxin | 0.0846479 |
| CALU | calumenin | 0.0827775 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0816696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0809297 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0769776 |
| JUN | jun proto-oncogene | 0.0754598 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0701326 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0701224 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0654936 |
| FMNL2 | formin-like 2 | 0.064463 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0620682 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0585724 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0572544 |
| CALR | calreticulin | 0.0532341 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0520044 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0513575 |
| SETBP1 | SET binding protein 1 | 0.0505041 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0503199 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0489165 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0476454 |
| MCL1 | myeloid cell leukemia 1 | 0.044895 |
| CD109 | CD109 molecule | 0.0428486 |
| CTTNBP2 | cortactin binding protein 2 | 0.0428037 |
| FLNB | filamin B, beta | 0.0403424 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0390354 |
| RPS27A | ribosomal protein S27a | 0.0386067 |
| PRELID2 | PRELI domain containing 2 | 0.0373247 |
| CDC73 | cell division cycle 73 | 0.0372935 |
| FRMD4A | FERM domain containing 4A | 0.0370312 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0367418 |
| COPA | coatomer protein complex, subunit alpha | 0.0360954 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0358698 |
| RTN4 | reticulon 4 | 0.0358296 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.03562 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.035473 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0341142 |
| FMN1 | formin 1 | 0.0331773 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0329833 |
| EMP1 | epithelial membrane protein 1 | 0.0320392 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.031961 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0318009 |
| RBM33 | RNA binding motif protein 33 | 0.0317518 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0317478 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0310206 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0309921 |
| HDAC9 | histone deacetylase 9 | 0.0309305 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0308902 |
| DIAPH2 | diaphanous-related formin 2 | 0.0308887 |
| LDHA | lactate dehydrogenase A | 0.0307905 |
| VMP1 | vacuole membrane protein 1 | 0.0307345 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0307165 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0306273 |
| ENO1 | enolase 1, (alpha) | 0.0299474 |
| AHNAK | AHNAK nucleoprotein | 0.0296372 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0296267 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0295743 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0291595 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0288049 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0286882 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0279847 |
| TFG | TRK-fused gene | 0.027868 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0277159 |
| SMYD3 | SET and MYND domain containing 3 | 0.0276531 |
| CCNL1 | cyclin L1 | 0.0272289 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0267364 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0266838 |
| CANX | calnexin | 0.0266838 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0265669 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.02649 |
| GLG1 | golgi glycoprotein 1 | 0.0262275 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0259086 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0255991 |
| VCL | vinculin | 0.0255369 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0254157 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.025188 |
| HMCN1 | hemicentin 1 | 0.0251013 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0250523 |
| ANO6 | anoctamin 6 | 0.0249165 |
| TMEM255B | transmembrane protein 255B | 0.0243779 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0240256 |
| MRTFA | myocardin related transcription factor A | 0.0238014 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0237758 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0235859 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0234623 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0233267 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0232937 |
| MTPN | myotrophin | 0.0232875 |
| UTRN | utrophin | 0.022969 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0229629 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0229492 |
| ZNF827 | zinc finger protein 827 | 0.0229222 |
| RCAN1 | regulator of calcineurin 1 | 0.0227351 |
| NUP58 | nucleoporin 58 | 0.0225435 |
| FAM168A | family with sequence similarity 168, member A | 0.0225214 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0223138 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.166379 |
| VGF | VGF nerve growth factor inducible | -0.166313 |
| MT2A | metallothionein 2A | -0.109257 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.108849 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0873949 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0766807 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0682909 |
| ACTG1 | actin gamma 1 | -0.0553225 |
| CENPF | centromere protein F, 350/400kDa | -0.0497279 |
| FN1 | fibronectin 1 | -0.0473464 |
| NAV2 | neuron navigator 2 | -0.0443208 |
| HLA-B | major histocompatibility complex, class I, B | -0.0422768 |
| TNNC1 | troponin C type 1 (slow) | -0.0422644 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.041994 |
| LAMB1 | laminin, beta 1 | -0.0411465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0403434 |
| PKM | pyruvate kinase, muscle | -0.035845 |
| RRBP1 | ribosome binding protein 1 | -0.0355305 |
| RPS6 | ribosomal protein S6 | -0.0340988 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0328966 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031653 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0304501 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0290327 |
| RPL19 | ribosomal protein L19 | -0.0282378 |
| B2M | beta-2-microglobulin | -0.0278815 |
| LMNA | lamin A/C | -0.0275658 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0268686 |
| CTSD | cathepsin D | -0.0266714 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0266211 |
| TRIM2 | tripartite motif containing 2 | -0.0265 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0260586 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0254783 |
| MKI67 | marker of proliferation Ki-67 | -0.0252075 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0251669 |
| TAGLN2 | transgelin 2 | -0.0250949 |
| GSN | gelsolin | -0.025005 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.024824 |
| GNAS | GNAS complex locus | -0.024636 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0244649 |
| NES | nestin | -0.0244508 |
| DCT | dopachrome tautomerase | -0.0243164 |
| RNF24 | ring finger protein 24 | -0.0242738 |
| SCFD2 | sec1 family domain containing 2 | -0.0242572 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0238143 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0237527 |
| CUX1 | cut-like homeobox 1 | -0.023703 |
| CAVIN1 | caveolae associated protein 1 | -0.0233695 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0228956 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0227085 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0227052 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0219292 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0218236 |
| GDF15 | growth differentiation factor 15 | -0.0218056 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.021594 |
| RPL9 | ribosomal protein L9 | -0.0212669 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0210954 |
| KPNB1 | karyopherin (importin) beta 1 | -0.02071 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0207005 |
| FTL | ferritin, light polypeptide | -0.0206698 |
| CALD1 | caldesmon 1 | -0.0205781 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0205051 |
| RPS19 | ribosomal protein S19 | -0.0204107 |
| A2M | alpha-2-macroglobulin | -0.0203848 |
| TMEM123 | transmembrane protein 123 | -0.0201494 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0200902 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0200114 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.019923 |
| PRAME | preferentially expressed antigen in melanoma | -0.0197846 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0197155 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194432 |
| RPL36 | ribosomal protein L36 | -0.0193887 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0193771 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0192278 |
| RPS29 | ribosomal protein S29 | -0.0190612 |
| RPL31 | ribosomal protein L31 | -0.0186699 |
| SFTPA2 | surfactant protein A2 | -0.0186319 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0185549 |
| PLIN2 | perilipin 2 | -0.0184782 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | -0.0183782 |
| CCDC91 | coiled-coil domain containing 91 | -0.0183122 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0182828 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0182121 |
| GHR | growth hormone receptor | -0.0182117 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0181938 |
| LRAT | lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) | -0.0181572 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0179874 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0179272 |
| HMGB1 | high mobility group box 1 | -0.0178879 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0174411 |
| RPS8 | ribosomal protein S8 | -0.0174224 |
| RPL34 | ribosomal protein L34 | -0.017245 |
| RPL35A | ribosomal protein L35a | -0.017214 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0171328 |
| RPL26 | ribosomal protein L26 | -0.0171049 |
| MED13 | mediator complex subunit 13 | -0.0169836 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0168445 |
| GOLGB1 | golgin B1 | -0.0165738 |
| GOLGA4 | golgin A4 | -0.0164627 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0164281 |
| IGF2 | insulin-like growth factor 2 | -0.0164084 |
