| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A1 | collagen, type V, alpha 1 | 0.162186 |
| ENO1 | enolase 1, (alpha) | 0.131368 |
| CD44 | CD44 molecule (Indian blood group) | 0.115484 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0991127 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0841542 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0802478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0747587 |
| TMSB10 | thymosin beta 10 | 0.0689543 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0610873 |
| MCL1 | myeloid cell leukemia 1 | 0.0577377 |
| POTEF | POTE ankyrin domain family, member F | 0.05759 |
| HMGA2 | high mobility group AT-hook 2 | 0.056109 |
| FLNB | filamin B, beta | 0.0557763 |
| TNS1 | tensin 1 | 0.0556032 |
| MLPH | melanophilin | 0.0545148 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0526418 |
| RRM2 | ribonucleotide reductase M2 | 0.0525143 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0510065 |
| FLNA | filamin A, alpha | 0.050962 |
| G0S2 | G0/G1 switch 2 | 0.0507266 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0503774 |
| NAV1 | neuron navigator 1 | 0.0493791 |
| KIAA1549L | KIAA1549-like | 0.0474698 |
| VEGFC | vascular endothelial growth factor C | 0.0444787 |
| AXL | AXL receptor tyrosine kinase | 0.0438698 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437169 |
| ACTN4 | actinin, alpha 4 | 0.043437 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.04091 |
| AHNAK | AHNAK nucleoprotein | 0.0408169 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0397706 |
| UBC | ubiquitin C | 0.039582 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0385221 |
| EMP1 | epithelial membrane protein 1 | 0.0383045 |
| ZNF638 | zinc finger protein 638 | 0.0379007 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0358023 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0357003 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0356987 |
| RPS27A | ribosomal protein S27a | 0.0354345 |
| MSN | moesin | 0.0352163 |
| TPM3 | tropomyosin 3 | 0.0345765 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0328795 |
| SEPTIN9 | septin 9 | 0.0328438 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0319733 |
| ANGPTL4 | angiopoietin-like 4 | 0.0315122 |
| MAP1B | microtubule-associated protein 1B | 0.031073 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0309188 |
| RAD51B | RAD51 paralog B | 0.0308493 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0307622 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0307483 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0301707 |
| DIAPH3 | diaphanous-related formin 3 | 0.0301361 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0291202 |
| PTK2 | protein tyrosine kinase 2 | 0.0290419 |
| MYO1D | myosin ID | 0.0290226 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0289719 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0289639 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0289596 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.02889 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0284831 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0283492 |
| PRKCA | protein kinase C, alpha | 0.0275822 |
| LDHA | lactate dehydrogenase A | 0.0273714 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0267996 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0264719 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0264094 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.025897 |
| SMAD3 | SMAD family member 3 | 0.0257457 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0256898 |
| CALR | calreticulin | 0.0256734 |
| IL11 | interleukin 11 | 0.0255623 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0255255 |
| RPS3 | ribosomal protein S3 | 0.0252965 |
| HMGA1 | high mobility group AT-hook 1 | 0.0251465 |
| DIAPH1 | diaphanous-related formin 1 | 0.0250101 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0249064 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0248855 |
| WWOX | WW domain containing oxidoreductase | 0.0248397 |
| CEP112 | centrosomal protein 112kDa | 0.0245173 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0242988 |
| SVIL | supervillin | 0.0242905 |
| MYO1E | myosin IE | 0.0238002 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.023527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0234838 |
| DEK | DEK proto-oncogene | 0.0234111 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.023218 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.023012 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0225209 |
| EXOC4 | exocyst complex component 4 | 0.0224315 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.022348 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0221895 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0221835 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0217199 |
| CCND1 | cyclin D1 | 0.021624 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0216188 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 0.0216052 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.021584 |
| LAMB3 | laminin, beta 3 | 0.0215592 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0214052 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0213425 |
| TPI1 | triosephosphate isomerase 1 | 0.0213217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.338052 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156677 |
| CDH13 | cadherin 13 | -0.141478 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.136149 |
| FN1 | fibronectin 1 | -0.136082 |
| IGF2 | insulin-like growth factor 2 | -0.123604 |
| VIM | vimentin | -0.0913644 |
| RPL35A | ribosomal protein L35a | -0.0803296 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0769455 |
| GOLGA4 | golgin A4 | -0.0756226 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0730103 |
| VCL | vinculin | -0.0720083 |
| RPS6 | ribosomal protein S6 | -0.0687747 |
| EGR1 | early growth response 1 | -0.0670412 |
| RPLP1 | ribosomal protein, large, P1 | -0.06434 |
| PTMA | prothymosin, alpha | -0.0630496 |
| CANX | calnexin | -0.0613328 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0608642 |
| LOX | lysyl oxidase | -0.0595122 |
| RAI14 | retinoic acid induced 14 | -0.0573783 |
| RRBP1 | ribosome binding protein 1 | -0.0547796 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0528763 |
| WDR45B | WD repeat domain 45B | -0.052207 |
| GNAS | GNAS complex locus | -0.0516162 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.046463 |
| SETD5 | SET domain containing 5 | -0.0463034 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.045284 |
| GLIS3 | GLIS family zinc finger 3 | -0.0447235 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.043029 |
| MT2A | metallothionein 2A | -0.0428331 |
| SPAG9 | sperm associated antigen 9 | -0.0426833 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0413237 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.041114 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0410308 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0406807 |
| TUBB6 | tubulin, beta 6 class V | -0.0401864 |
| GLG1 | golgi glycoprotein 1 | -0.0400456 |
| TNNC1 | troponin C type 1 (slow) | -0.0398491 |
| NDRG1 | N-myc downstream regulated 1 | -0.0396235 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0396129 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0394804 |
| RPL34 | ribosomal protein L34 | -0.0393125 |
| TENM2 | teneurin transmembrane protein 2 | -0.0390948 |
| MT1X | metallothionein 1X | -0.0384305 |
| MAP4 | microtubule-associated protein 4 | -0.0371538 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0369868 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0367101 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0362013 |
| NGLY1 | N-glycanase 1 | -0.0357049 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347261 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0345567 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0344055 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0343166 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0342441 |
| CLMP | CXADR-like membrane protein | -0.0334166 |
| CD109 | CD109 molecule | -0.0332736 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0329497 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0322347 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0319316 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0314865 |
| JMJD1C | jumonji domain containing 1C | -0.0311561 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0309068 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0305229 |
| USP3 | ubiquitin specific peptidase 3 | -0.0304381 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0303432 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0303141 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0295962 |
| QKI | QKI, KH domain containing, RNA binding | -0.0295221 |
| FAM13A | family with sequence similarity 13, member A | -0.0292936 |
| MORF4L2 | mortality factor 4 like 2 | -0.0292253 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0290225 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0289732 |
| CADM1 | cell adhesion molecule 1 | -0.0284127 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0281836 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0280675 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0279231 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0278376 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0276047 |
| HDLBP | high density lipoprotein binding protein | -0.0274052 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0273383 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.0271585 |
| TRAM1 | translocation associated membrane protein 1 | -0.0270527 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0269754 |
| IER3 | immediate early response 3 | -0.0268271 |
| FAM162A | family with sequence similarity 162, member A | -0.0268139 |
| MATR3 | matrin 3 | -0.0267012 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0266966 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0265173 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0263148 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0263018 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0260813 |
| RTN4 | reticulon 4 | -0.0257644 |
| RPL19 | ribosomal protein L19 | -0.0257344 |
| TAOK1 | TAO kinase 1 | -0.0255623 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0255114 |
| HELZ | helicase with zinc finger | -0.0254373 |
| TMEM165 | transmembrane protein 165 | -0.0254041 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0252309 |
| FOXJ3 | forkhead box J3 | -0.0251864 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0251016 |
