| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.163604 |
| CDH13 | cadherin 13 | 0.0936558 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0625133 |
| COL5A1 | collagen, type V, alpha 1 | 0.0610071 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0573961 |
| ATP13A3 | ATPase type 13A3 | 0.0570789 |
| CADM1 | cell adhesion molecule 1 | 0.0548519 |
| FBN1 | fibrillin 1 | 0.0523966 |
| PDE10A | phosphodiesterase 10A | 0.0503406 |
| AHNAK | AHNAK nucleoprotein | 0.0494361 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0484168 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0459834 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0454183 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0453216 |
| UBC | ubiquitin C | 0.0444016 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0436066 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0406967 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0404406 |
| CALU | calumenin | 0.0402316 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0392116 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0364881 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326759 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0305468 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0290596 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0280365 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0273187 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0272512 |
| APP | amyloid beta (A4) precursor protein | 0.0258959 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0255332 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0253679 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.025233 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0244205 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0242317 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242315 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0240242 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0240221 |
| JUN | jun proto-oncogene | 0.0234381 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0233537 |
| SAFB2 | scaffold attachment factor B2 | 0.0231578 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0229991 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0228273 |
| CCNY | cyclin Y | 0.0227486 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0226422 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0225705 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0222181 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0221199 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0220621 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0219538 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.021174 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0207815 |
| FLNA | filamin A, alpha | 0.0202239 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0201161 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0199738 |
| GOLGB1 | golgin B1 | 0.0199485 |
| VMP1 | vacuole membrane protein 1 | 0.0198151 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.019576 |
| CALD1 | caldesmon 1 | 0.0194969 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0193264 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0191002 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0190767 |
| TFG | TRK-fused gene | 0.0190537 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0188803 |
| TNS1 | tensin 1 | 0.0188174 |
| COL1A1 | collagen, type I, alpha 1 | 0.0186954 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0183091 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0182702 |
| FNIP1 | folliculin interacting protein 1 | 0.0181563 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0179764 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0177009 |
| NBAS | neuroblastoma amplified sequence | 0.0176722 |
| CMIP | c-Maf inducing protein | 0.0176444 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0175741 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0174714 |
| COPA | coatomer protein complex, subunit alpha | 0.0174595 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0173707 |
| USP34 | ubiquitin specific peptidase 34 | 0.0173533 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0171967 |
| FMNL2 | formin-like 2 | 0.0169975 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0169884 |
| CDK13 | cyclin-dependent kinase 13 | 0.016881 |
| PCBP2 | poly(rC) binding protein 2 | 0.0167481 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0166471 |
| CANX | calnexin | 0.0164963 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0164583 |
| SDC2 | syndecan 2 | 0.0164098 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.016403 |
| ENO1 | enolase 1, (alpha) | 0.0163865 |
| RUNX1 | runt-related transcription factor 1 | 0.0163504 |
| SPAG9 | sperm associated antigen 9 | 0.0159854 |
| RBM39 | RNA binding motif protein 39 | 0.0159416 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.015822 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0157556 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0157239 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0156178 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0155891 |
| ASPH | aspartate beta-hydroxylase | 0.0155468 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0155282 |
| SIK3 | SIK family kinase 3 | 0.0154968 |
| CLIC4 | chloride intracellular channel 4 | 0.0152654 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0152401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.291035 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.267078 |
| VIM | vimentin | -0.141436 |
| TMSB10 | thymosin beta 10 | -0.116916 |
| RPS6 | ribosomal protein S6 | -0.0891307 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0794587 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0792569 |
| RPL35A | ribosomal protein L35a | -0.0779709 |
| FTL | ferritin, light polypeptide | -0.0761353 |
| RPS8 | ribosomal protein S8 | -0.0639421 |
| HLA-B | major histocompatibility complex, class I, B | -0.063285 |
| PTMA | prothymosin, alpha | -0.0606194 |
| MT1X | metallothionein 1X | -0.0561036 |
| RPS19 | ribosomal protein S19 | -0.0554919 |
| RPLP1 | ribosomal protein, large, P1 | -0.0543672 |
| B2M | beta-2-microglobulin | -0.0497755 |
| CD44 | CD44 molecule (Indian blood group) | -0.048246 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.045529 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0447213 |
| RPL12 | ribosomal protein L12 | -0.0445474 |
| RPL23 | ribosomal protein L23 | -0.0438321 |
| RPL36 | ribosomal protein L36 | -0.0435538 |
| RPL11 | ribosomal protein L11 | -0.0410158 |
| RPL8 | ribosomal protein L8 | -0.0409195 |
| RPLP2 | ribosomal protein, large, P2 | -0.0401613 |
| RPS21 | ribosomal protein S21 | -0.0399798 |
| RPL32 | ribosomal protein L32 | -0.0389762 |
| RPL28 | ribosomal protein L28 | -0.0386484 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0383858 |
| RPL19 | ribosomal protein L19 | -0.0381773 |
| RPL34 | ribosomal protein L34 | -0.0377253 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0351558 |
| S100A9 | S100 calcium binding protein A9 | -0.0346291 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0343722 |
| S100A6 | S100 calcium binding protein A6 | -0.0340349 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.033269 |
| STC1 | stanniocalcin 1 | -0.0332567 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0330846 |
| RPL7 | ribosomal protein L7 | -0.0323065 |
| FN1 | fibronectin 1 | -0.0321844 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0311206 |
| RPS11 | ribosomal protein S11 | -0.0306881 |
| CAVIN1 | caveolae associated protein 1 | -0.0305694 |
| RPL31 | ribosomal protein L31 | -0.0298504 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0293493 |
| RPS5 | ribosomal protein S5 | -0.0292008 |
| RPS23 | ribosomal protein S23 | -0.0287708 |
| RPS13 | ribosomal protein S13 | -0.0285174 |
| PKM | pyruvate kinase, muscle | -0.0280143 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0269279 |
| RPL5 | ribosomal protein L5 | -0.0267477 |
| RPS14 | ribosomal protein S14 | -0.0267345 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0265716 |
| S100A10 | S100 calcium binding protein A10 | -0.0262464 |
| RPS20 | ribosomal protein S20 | -0.0261895 |
| RPL30 | ribosomal protein L30 | -0.0261212 |
| RPL26 | ribosomal protein L26 | -0.0260873 |
| RPS15 | ribosomal protein S15 | -0.0259602 |
| RPL35 | ribosomal protein L35 | -0.0253124 |
| RPS16 | ribosomal protein S16 | -0.0251454 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0247614 |
| RPLP0 | ribosomal protein, large, P0 | -0.0236053 |
| RPL18 | ribosomal protein L18 | -0.02328 |
| RACK1 | receptor for activated C kinase 1 | -0.023251 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0230953 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0229261 |
| PFN1 | profilin 1 | -0.0227891 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0227641 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0224995 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0222032 |
| RRBP1 | ribosome binding protein 1 | -0.0221525 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0220411 |
| RPL38 | ribosomal protein L38 | -0.0219974 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0219582 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0216953 |
| TPI1 | triosephosphate isomerase 1 | -0.0216281 |
| RPS12 | ribosomal protein S12 | -0.0215334 |
| RPS27 | ribosomal protein S27 | -0.0212778 |
| TMSB4X | thymosin beta 4, X-linked | -0.0211916 |
| SERF2 | small EDRK-rich factor 2 | -0.0210413 |
| ANXA2 | annexin A2 | -0.0210359 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0209853 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0209234 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0208847 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0208153 |
| RPL27 | ribosomal protein L27 | -0.0208091 |
| RPL37A | ribosomal protein L37a | -0.0207574 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0207393 |
| CST3 | cystatin C | -0.0207061 |
| RPS29 | ribosomal protein S29 | -0.0205576 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0205408 |
| RPS25 | ribosomal protein S25 | -0.0204301 |
| HLA-A | major histocompatibility complex, class I, A | -0.0201391 |
| RPS24 | ribosomal protein S24 | -0.0198362 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0196939 |
| ACTG1 | actin gamma 1 | -0.0196267 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.019527 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0193795 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0191445 |
| EGR1 | early growth response 1 | -0.0184802 |
