| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.169259 |
| LMO7 | LIM domain 7 | 0.156671 |
| UBC | ubiquitin C | 0.155069 |
| EZR | ezrin | 0.12042 |
| JUN | jun proto-oncogene | 0.10864 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.104528 |
| RPS27A | ribosomal protein S27a | 0.103502 |
| EXT1 | exostosin glycosyltransferase 1 | 0.103411 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0983442 |
| EMP1 | epithelial membrane protein 1 | 0.0887566 |
| KRT20 | keratin 20, type I | 0.0872411 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0786689 |
| PTMA | prothymosin, alpha | 0.0772622 |
| NDRG1 | N-myc downstream regulated 1 | 0.0758181 |
| RPS3 | ribosomal protein S3 | 0.0667609 |
| ENO1 | enolase 1, (alpha) | 0.0661973 |
| CALR | calreticulin | 0.0611545 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0592465 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0588707 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.05848 |
| EXPH5 | exophilin 5 | 0.0572971 |
| LDHA | lactate dehydrogenase A | 0.0568211 |
| ATF3 | activating transcription factor 3 | 0.0566957 |
| FBXO32 | F-box protein 32 | 0.0538 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0511069 |
| CALU | calumenin | 0.0503655 |
| SQSTM1 | sequestosome 1 | 0.0499154 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0495457 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0494349 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0492107 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.048695 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0483782 |
| CANX | calnexin | 0.0479178 |
| HDLBP | high density lipoprotein binding protein | 0.0470852 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.046949 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0467286 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0459684 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0436528 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0434418 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.043054 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0420074 |
| TRIB1 | tribbles pseudokinase 1 | 0.0413993 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0389332 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0385245 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0381545 |
| SGMS2 | sphingomyelin synthase 2 | 0.0369732 |
| HKDC1 | hexokinase domain containing 1 | 0.0366814 |
| MYADM | myeloid-associated differentiation marker | 0.0359254 |
| AREG | amphiregulin | 0.0357822 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0357086 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0353394 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0353063 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0351313 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342811 |
| FAM13A | family with sequence similarity 13, member A | 0.0338645 |
| HM13 | histocompatibility (minor) 13 | 0.0336075 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0335449 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0334461 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0332536 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0323398 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0320363 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0319181 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.0319161 |
| SET | SET nuclear proto-oncogene | 0.0317159 |
| PLK2 | polo-like kinase 2 | 0.0314837 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0313722 |
| ACTN4 | actinin, alpha 4 | 0.0312824 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0309706 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0307622 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0304102 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.030066 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0300467 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0293668 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0292711 |
| CLPTM1L | CLPTM1-like | 0.0291434 |
| TJP1 | tight junction protein 1 | 0.0289078 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0285855 |
| CCNY | cyclin Y | 0.0284878 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0281242 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0279726 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0271726 |
| AHNAK | AHNAK nucleoprotein | 0.0271351 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0270416 |
| ADIPOR2 | adiponectin receptor 2 | 0.0269834 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.02615 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0261245 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0258659 |
| RACK1 | receptor for activated C kinase 1 | 0.0254334 |
| ANXA1 | annexin A1 | 0.0253782 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0252273 |
| TMC5 | transmembrane channel-like 5 | 0.0249409 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0246944 |
| XPOT | exportin, tRNA | 0.0241343 |
| TSPAN3 | tetraspanin 3 | 0.0241308 |
| MPZL3 | myelin protein zero-like 3 | 0.0241291 |
| MLPH | melanophilin | 0.0239561 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0239506 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0238909 |
| ASPH | aspartate beta-hydroxylase | 0.0238887 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0235844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.176405 |
| RPL35A | ribosomal protein L35a | -0.112876 |
| RPLP1 | ribosomal protein, large, P1 | -0.0851244 |
| RPS19 | ribosomal protein S19 | -0.0806901 |
| EGR1 | early growth response 1 | -0.0775825 |
| RPL23 | ribosomal protein L23 | -0.0689256 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0629614 |
| LYZ | lysozyme | -0.0623271 |
| RPLP2 | ribosomal protein, large, P2 | -0.0586685 |
| RPS13 | ribosomal protein S13 | -0.0516992 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.048415 |
| RPL21 | ribosomal protein L21 | -0.0473211 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0472695 |
| RPL34 | ribosomal protein L34 | -0.0450282 |
| MKI67 | marker of proliferation Ki-67 | -0.0432026 |
| B2M | beta-2-microglobulin | -0.0418671 |
| RPL11 | ribosomal protein L11 | -0.0412166 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0410087 |
| SMAD3 | SMAD family member 3 | -0.0405313 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0398148 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0394375 |
| PLEC | plectin | -0.0391081 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0389604 |
| RPL28 | ribosomal protein L28 | -0.0387711 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.037727 |
| RPL35 | ribosomal protein L35 | -0.0376775 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0371326 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0366129 |
| KRT19 | keratin 19, type I | -0.0362913 |
| RPL5 | ribosomal protein L5 | -0.0362604 |
| INTS6 | integrator complex subunit 6 | -0.0355676 |
| TXNRD1 | thioredoxin reductase 1 | -0.0353543 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0350407 |
| GNAS | GNAS complex locus | -0.0346867 |
| RPL31 | ribosomal protein L31 | -0.0344763 |
| POTEF | POTE ankyrin domain family, member F | -0.0343695 |
| PKM | pyruvate kinase, muscle | -0.0335189 |
| STK24 | serine/threonine kinase 24 | -0.0333295 |
| RPL19 | ribosomal protein L19 | -0.0333095 |
| RPL9 | ribosomal protein L9 | -0.0332024 |
| RPS21 | ribosomal protein S21 | -0.0324484 |
| RPS11 | ribosomal protein S11 | -0.0323805 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0322121 |
| RPS16 | ribosomal protein S16 | -0.0320938 |
| JUP | junction plakoglobin | -0.0317515 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0313447 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0311671 |
| RPS29 | ribosomal protein S29 | -0.0310082 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0305933 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0304284 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0303813 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0301943 |
| FRY | furry homolog (Drosophila) | -0.0299886 |
| HMGB1 | high mobility group box 1 | -0.0299212 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0297388 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0290438 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0282198 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0279476 |
| RPS23 | ribosomal protein S23 | -0.0279439 |
| RPS14 | ribosomal protein S14 | -0.0271402 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0270719 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0268644 |
| FOSL1 | FOS-like antigen 1 | -0.0267628 |
| RPS8 | ribosomal protein S8 | -0.0267428 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0266993 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0262432 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0260591 |
| IRF1 | interferon regulatory factor 1 | -0.0260546 |
| VCL | vinculin | -0.0259125 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0258485 |
| TMSB10 | thymosin beta 10 | -0.0255091 |
| IL6ST | interleukin 6 signal transducer | -0.0253755 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0253711 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0253629 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0253055 |
| RPL36 | ribosomal protein L36 | -0.0251075 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0250945 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0249992 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0247521 |
| ANLN | anillin, actin binding protein | -0.0245622 |
| CCNL1 | cyclin L1 | -0.0243108 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0241001 |
| CLDN4 | claudin 4 | -0.0239134 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0238698 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.023553 |
| SKIL | SKI-like proto-oncogene | -0.023457 |
| PRDX1 | peroxiredoxin 1 | -0.0231819 |
| CDK6 | cyclin-dependent kinase 6 | -0.0231353 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0228707 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0228161 |
| MSN | moesin | -0.0225971 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.022516 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0224706 |
| GSE1 | Gse1 coiled-coil protein | -0.0224268 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.022122 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0219847 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.0219479 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0218965 |
| ATF4 | activating transcription factor 4 | -0.0218799 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0218494 |
