| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS27A | ribosomal protein S27a | 0.177188 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.162679 |
| UBC | ubiquitin C | 0.137938 |
| PCBP2 | poly(rC) binding protein 2 | 0.0956748 |
| FLNB | filamin B, beta | 0.0953161 |
| FAT1 | FAT atypical cadherin 1 | 0.0772803 |
| ENO1 | enolase 1, (alpha) | 0.076246 |
| TMSB10 | thymosin beta 10 | 0.074696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.068962 |
| RPS3 | ribosomal protein S3 | 0.0672088 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0643831 |
| JUN | jun proto-oncogene | 0.063938 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0625531 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0610801 |
| EZR | ezrin | 0.0559783 |
| LDHA | lactate dehydrogenase A | 0.0540757 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0497308 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.048837 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0469227 |
| CALU | calumenin | 0.0469212 |
| PKM | pyruvate kinase, muscle | 0.0443944 |
| ASPH | aspartate beta-hydroxylase | 0.0426313 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0422099 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0410967 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0403599 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0388608 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0388417 |
| AHNAK | AHNAK nucleoprotein | 0.037928 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0378669 |
| PGK1 | phosphoglycerate kinase 1 | 0.0369154 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0362203 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0357662 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0354448 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0343983 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340849 |
| NRDC | nardilysin convertase | 0.0340583 |
| MYOF | myoferlin | 0.0334097 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0333731 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.033188 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0310432 |
| AUTS2 | autism susceptibility candidate 2 | 0.0307109 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0305133 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0296222 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.029469 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0292207 |
| CALR | calreticulin | 0.0289462 |
| CCNY | cyclin Y | 0.0278638 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0277964 |
| UBE3C | ubiquitin protein ligase E3C | 0.0277537 |
| CANX | calnexin | 0.027697 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0276471 |
| ITGB4 | integrin, beta 4 | 0.02759 |
| ZNF292 | zinc finger protein 292 | 0.0267825 |
| PDZD8 | PDZ domain containing 8 | 0.0265349 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0264631 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0261572 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0259538 |
| MSI2 | musashi RNA-binding protein 2 | 0.0256703 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0256677 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0254693 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0254629 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0250733 |
| EMP1 | epithelial membrane protein 1 | 0.0247258 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0245828 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0244414 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024317 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0237496 |
| SAFB2 | scaffold attachment factor B2 | 0.0236877 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0236471 |
| ZNF638 | zinc finger protein 638 | 0.0234639 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0225962 |
| XPO1 | exportin 1 | 0.0225068 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0220384 |
| CCNI | cyclin I | 0.0220294 |
| USP3 | ubiquitin specific peptidase 3 | 0.0219951 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0218772 |
| EP400 | E1A binding protein p400 | 0.0218469 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0217893 |
| POTEF | POTE ankyrin domain family, member F | 0.021637 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0216273 |
| VMP1 | vacuole membrane protein 1 | 0.0215532 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0210701 |
| AFDN | afadin, adherens junction formation factor | 0.0210568 |
| PTEN | phosphatase and tensin homolog | 0.0210037 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.020901 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0208492 |
| HDLBP | high density lipoprotein binding protein | 0.0202854 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0199392 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0198997 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0196647 |
| RBM25 | RNA binding motif protein 25 | 0.0193778 |
| RNF10 | ring finger protein 10 | 0.0193203 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0192228 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0191304 |
| ZNF148 | zinc finger protein 148 | 0.01903 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0190048 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0189857 |
| TXNIP | thioredoxin interacting protein | 0.0189253 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0189154 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0186804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.230739 |
| RPL35A | ribosomal protein L35a | -0.138477 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.132059 |
| MYO1E | myosin IE | -0.130884 |
| RPLP1 | ribosomal protein, large, P1 | -0.10436 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101705 |
| LMO7 | LIM domain 7 | -0.0848529 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0810354 |
| RPS23 | ribosomal protein S23 | -0.0806054 |
| RPL34 | ribosomal protein L34 | -0.0771364 |
| RPS2 | ribosomal protein S2 | -0.0748593 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0733216 |
| FRMD5 | FERM domain containing 5 | -0.0709951 |
| VCL | vinculin | -0.0693666 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0678405 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.064488 |
| RPS19 | ribosomal protein S19 | -0.0625008 |
| RPS8 | ribosomal protein S8 | -0.0621133 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.061725 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.055802 |
| TSPAN8 | tetraspanin 8 | -0.0539182 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.05382 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0537201 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0536665 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0526652 |
| PRSS3 | protease, serine, 3 | -0.0515795 |
| CLIC5 | chloride intracellular channel 5 | -0.0498599 |
| SP100 | SP100 nuclear antigen | -0.0487125 |
| RIGI | RNA sensor RIG-I | -0.0485317 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0465462 |
| RPS25 | ribosomal protein S25 | -0.0464813 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0461522 |
| MCU | mitochondrial calcium uniporter | -0.0448215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0439035 |
| RPS29 | ribosomal protein S29 | -0.0431613 |
| RPS16 | ribosomal protein S16 | -0.0408757 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0407428 |
| RPS24 | ribosomal protein S24 | -0.0406928 |
| DSG2 | desmoglein 2 | -0.0403946 |
| CUX1 | cut-like homeobox 1 | -0.0401519 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.040108 |
| RPL11 | ribosomal protein L11 | -0.0400525 |
| RPL31 | ribosomal protein L31 | -0.0400391 |
| RPS20 | ribosomal protein S20 | -0.040012 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0393825 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0389687 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0380083 |
| DSG3 | desmoglein 3 | -0.037341 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0370315 |
| TJP1 | tight junction protein 1 | -0.0369809 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0369535 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0365882 |
| RPL12 | ribosomal protein L12 | -0.0365228 |
| JMJD1C | jumonji domain containing 1C | -0.0360778 |
| RPLP2 | ribosomal protein, large, P2 | -0.0357257 |
| RPL38 | ribosomal protein L38 | -0.035725 |
| RPS27 | ribosomal protein S27 | -0.0350161 |
| RPL19 | ribosomal protein L19 | -0.0349211 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.034433 |
| RPS21 | ribosomal protein S21 | -0.0340775 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0338314 |
| RPLP0 | ribosomal protein, large, P0 | -0.0337921 |
| FBXO11 | F-box protein 11 | -0.0335509 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0323233 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0322468 |
| ANXA2 | annexin A2 | -0.0322009 |
| PALLD | palladin, cytoskeletal associated protein | -0.0321558 |
| RPS13 | ribosomal protein S13 | -0.0316151 |
| SERINC5 | serine incorporator 5 | -0.0304398 |
| INTS6 | integrator complex subunit 6 | -0.0303584 |
| XAF1 | XIAP associated factor 1 | -0.0297622 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0297448 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0296196 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0294709 |
| NPSR1 | neuropeptide S receptor 1 | -0.0292884 |
| RPS14 | ribosomal protein S14 | -0.0289944 |
| MTAP | methylthioadenosine phosphorylase | -0.0285932 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0284273 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0282254 |
| RPS10 | ribosomal protein S10 | -0.0279656 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0279641 |
| RPL26 | ribosomal protein L26 | -0.0278004 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0276442 |
| HLA-B | major histocompatibility complex, class I, B | -0.0276064 |
| LAMA4 | laminin, alpha 4 | -0.0275139 |
| RNF213 | ring finger protein 213 | -0.0273488 |
| DSPP | dentin sialophosphoprotein | -0.0268157 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0267215 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0266252 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0264129 |
| RPL36A | ribosomal protein L36a | -0.0262794 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0262381 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0261969 |
| RPL35 | ribosomal protein L35 | -0.0261626 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0257892 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0256863 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0256488 |
| SNX14 | sorting nexin 14 | -0.0250498 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0240065 |
| RPS17 | ribosomal protein S17 | -0.0239702 |
