| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.159581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0919428 |
| FAM20C | family with sequence similarity 20, member C | 0.0821152 |
| SMAD3 | SMAD family member 3 | 0.0773625 |
| NAV2 | neuron navigator 2 | 0.0757517 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0691158 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0642768 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0534694 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0526916 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.051144 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0487027 |
| INTS6 | integrator complex subunit 6 | 0.0468363 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0462614 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0462387 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0440043 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0418935 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0416413 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.040164 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0393786 |
| MCL1 | myeloid cell leukemia 1 | 0.0391879 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0386148 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0381555 |
| ATXN1 | ataxin 1 | 0.0381008 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.036939 |
| UBC | ubiquitin C | 0.0361411 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0361104 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348902 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0339288 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0335074 |
| EFNA5 | ephrin-A5 | 0.0323796 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0320103 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0317814 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0316248 |
| NDRG1 | N-myc downstream regulated 1 | 0.0315515 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0310309 |
| TGFB1 | transforming growth factor, beta 1 | 0.0306999 |
| PRELID2 | PRELI domain containing 2 | 0.0305521 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0304764 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.030448 |
| PKM | pyruvate kinase, muscle | 0.0303464 |
| FLNB | filamin B, beta | 0.0300057 |
| EGFR | epidermal growth factor receptor | 0.0297303 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0296241 |
| AADAC | arylacetamide deacetylase | 0.0289944 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0287792 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0285856 |
| TGM2 | transglutaminase 2 | 0.0284187 |
| ZNF638 | zinc finger protein 638 | 0.0277727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0276224 |
| MYOF | myoferlin | 0.0274048 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0273503 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0269378 |
| SEPTIN9 | septin 9 | 0.0268748 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0259724 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0253837 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0253459 |
| RUNX1 | runt-related transcription factor 1 | 0.025153 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0250939 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0248576 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0245076 |
| TUT7 | terminal uridylyl transferase 7 | 0.0243666 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0243421 |
| NABP1 | nucleic acid binding protein 1 | 0.0242801 |
| JUN | jun proto-oncogene | 0.0242409 |
| ACTN4 | actinin, alpha 4 | 0.0236788 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0235511 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0233511 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0228987 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0227642 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0224906 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0223512 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0222825 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0221874 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0220219 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0217425 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0217269 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0214902 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0214539 |
| LOXL2 | lysyl oxidase-like 2 | 0.0214109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0213541 |
| COPA | coatomer protein complex, subunit alpha | 0.0213466 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0211577 |
| STK38L | serine/threonine kinase 38 like | 0.0209976 |
| NPTN | neuroplastin | 0.0209753 |
| BRD2 | bromodomain containing 2 | 0.0209322 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0208247 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0207449 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0207429 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0203574 |
| GPATCH2L | G patch domain containing 2-like | 0.0201126 |
| ASPH | aspartate beta-hydroxylase | 0.0200043 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.019931 |
| CTBP2 | C-terminal binding protein 2 | 0.0199032 |
| TOP1 | topoisomerase (DNA) I | 0.0197733 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0197246 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.019717 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0195984 |
| CALU | calumenin | 0.0195859 |
| FLNA | filamin A, alpha | 0.0195483 |
| SRP54 | signal recognition particle 54kDa | 0.0195374 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.135694 |
| TMSB10 | thymosin beta 10 | -0.133915 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.129917 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109762 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0965115 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0942305 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.079815 |
| OSMR | oncostatin M receptor | -0.0721467 |
| VIM | vimentin | -0.0701522 |
| NRG1 | neuregulin 1 | -0.066052 |
| FTL | ferritin, light polypeptide | -0.0657857 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0632687 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0609458 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0580174 |
| PTMA | prothymosin, alpha | -0.0558404 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0534284 |
| S100A6 | S100 calcium binding protein A6 | -0.0517082 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0498551 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.046917 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0457801 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0450904 |
| STC1 | stanniocalcin 1 | -0.0437763 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0436871 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0436603 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435161 |
| GLCCI1 | glucocorticoid induced 1 | -0.0425384 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0420012 |
| IER3 | immediate early response 3 | -0.0413422 |
| RPS19 | ribosomal protein S19 | -0.0406859 |
| RPLP1 | ribosomal protein, large, P1 | -0.0399452 |
| MECOM | MDS1 and EVI1 complex locus | -0.039719 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0379869 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0379527 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0375807 |
| TMSB4X | thymosin beta 4, X-linked | -0.0375233 |
| PRRX1 | paired related homeobox 1 | -0.0373126 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0364172 |
| RAI14 | retinoic acid induced 14 | -0.0359902 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.035889 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0357932 |
| RPL34 | ribosomal protein L34 | -0.0357391 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0353987 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0351761 |
| RPL35A | ribosomal protein L35a | -0.0351501 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0350639 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0346219 |
| NRP1 | neuropilin 1 | -0.0344135 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0340605 |
| RPS21 | ribosomal protein S21 | -0.0335645 |
| CDCP1 | CUB domain containing protein 1 | -0.0335553 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0322132 |
| S100A10 | S100 calcium binding protein A10 | -0.0316947 |
| CLMP | CXADR-like membrane protein | -0.0313016 |
| RPL36 | ribosomal protein L36 | -0.0311682 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0308909 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0295555 |
| PGK1 | phosphoglycerate kinase 1 | -0.0295141 |
| CDK14 | cyclin-dependent kinase 14 | -0.0293936 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0278786 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0277014 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0274147 |
| MTSS1 | metastasis suppressor 1 | -0.027371 |
| MEF2A | myocyte enhancer factor 2A | -0.0268005 |
| VRK2 | vaccinia related kinase 2 | -0.026669 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0265239 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0264396 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0262575 |
| RPL32 | ribosomal protein L32 | -0.0260372 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0260237 |
| SLC38A1 | solute carrier family 38, member 1 | -0.026022 |
| AOPEP | aminopeptidase O (putative) | -0.0256753 |
| RPLP2 | ribosomal protein, large, P2 | -0.02548 |
| RPS29 | ribosomal protein S29 | -0.0254319 |
| SYT1 | synaptotagmin I | -0.0254062 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.025308 |
| CDH13 | cadherin 13 | -0.0252448 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0245043 |
| SNX9 | sorting nexin 9 | -0.0244923 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0244614 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0242878 |
| IL1B | interleukin 1, beta | -0.0238517 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0236128 |
| BMERB1 | bMERB domain containing 1 | -0.0235613 |
| TMEM131 | transmembrane protein 131 | -0.0234709 |
| TPM4 | tropomyosin 4 | -0.0233471 |
| RUNX2 | runt-related transcription factor 2 | -0.0232321 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0232028 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0231936 |
| CP | ceruloplasmin (ferroxidase) | -0.0231 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0230094 |
| RPS13 | ribosomal protein S13 | -0.0229356 |
| RPS24 | ribosomal protein S24 | -0.0228882 |
| JMJD1C | jumonji domain containing 1C | -0.0227088 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0226811 |
| ETV6 | ets variant 6 | -0.0226266 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0226178 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0225141 |
| LOX | lysyl oxidase | -0.0224584 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0224308 |
| HLA-B | major histocompatibility complex, class I, B | -0.022233 |
