| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.112171 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102325 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0912588 |
| ASPH | aspartate beta-hydroxylase | 0.0905302 |
| UBC | ubiquitin C | 0.0892984 |
| EXT1 | exostosin glycosyltransferase 1 | 0.088056 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0878833 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0797746 |
| VIM | vimentin | 0.0793841 |
| MT2A | metallothionein 2A | 0.0773588 |
| PDE10A | phosphodiesterase 10A | 0.0760837 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.070268 |
| PARD3 | par-3 family cell polarity regulator | 0.0702204 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.068361 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0666513 |
| MYOF | myoferlin | 0.0663227 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.062835 |
| VMP1 | vacuole membrane protein 1 | 0.0624682 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0622086 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0613723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0597326 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0582604 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0580382 |
| VCL | vinculin | 0.0578937 |
| PRKCA | protein kinase C, alpha | 0.056888 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0545932 |
| FN1 | fibronectin 1 | 0.0544834 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0534047 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0532523 |
| TCF12 | transcription factor 12 | 0.0530322 |
| ENO1 | enolase 1, (alpha) | 0.0515083 |
| PTK2 | protein tyrosine kinase 2 | 0.0507306 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0494614 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0489345 |
| AHNAK | AHNAK nucleoprotein | 0.0486272 |
| SP100 | SP100 nuclear antigen | 0.0477894 |
| MYO1E | myosin IE | 0.0472423 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0464942 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0458064 |
| RYK | receptor-like tyrosine kinase | 0.045442 |
| JUN | jun proto-oncogene | 0.0453102 |
| CANX | calnexin | 0.044849 |
| EXOC6B | exocyst complex component 6B | 0.0446223 |
| APP | amyloid beta (A4) precursor protein | 0.0440505 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0438619 |
| NCKAP1 | NCK-associated protein 1 | 0.04372 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0436529 |
| ACTN4 | actinin, alpha 4 | 0.0432932 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0428632 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0427245 |
| CCNY | cyclin Y | 0.0413574 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0402031 |
| AOPEP | aminopeptidase O (putative) | 0.0401612 |
| PHIP | pleckstrin homology domain interacting protein | 0.0401576 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0399443 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0391178 |
| NAV1 | neuron navigator 1 | 0.0388272 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0386699 |
| YTHDC1 | YTH domain containing 1 | 0.038397 |
| H3-3B | H3.3 histone B | 0.0382286 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0377786 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0372104 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0370404 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0365862 |
| RUNX1 | runt-related transcription factor 1 | 0.0358007 |
| NF1 | neurofibromin 1 | 0.0357218 |
| EXOC4 | exocyst complex component 4 | 0.0355109 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0347121 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0342135 |
| NCOA3 | nuclear receptor coactivator 3 | 0.034009 |
| SPAG9 | sperm associated antigen 9 | 0.0339354 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0337451 |
| ZNF106 | zinc finger protein 106 | 0.0336906 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0336795 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.033401 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0330589 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0329586 |
| GPHN | gephyrin | 0.0327169 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0325834 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.031967 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0317691 |
| CCNI | cyclin I | 0.0317377 |
| RB1 | retinoblastoma 1 | 0.0315539 |
| AHR | aryl hydrocarbon receptor | 0.0315374 |
| EHBP1 | EH domain binding protein 1 | 0.0314926 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0308957 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0307152 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.03063 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0304823 |
| RNF213 | ring finger protein 213 | 0.0302267 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0302057 |
| ATXN1 | ataxin 1 | 0.0301303 |
| HIP1 | huntingtin interacting protein 1 | 0.0300069 |
| MYO5B | myosin VB | 0.02997 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0298774 |
| RPLP1 | ribosomal protein, large, P1 | 0.029863 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0295967 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0295687 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0295321 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0293996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.113862 |
| LAMB3 | laminin, beta 3 | -0.112296 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0955501 |
| TMEM165 | transmembrane protein 165 | -0.0688079 |
| ATOSA | atos homolog A | -0.0642904 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0639645 |
| KRT17 | keratin 17, type I | -0.0606281 |
| IGF2 | insulin-like growth factor 2 | -0.0591079 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0586351 |
| DTNA | dystrobrevin, alpha | -0.0564821 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0547889 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0537421 |
| JUP | junction plakoglobin | -0.0494316 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.048553 |
| KLHL24 | kelch-like family member 24 | -0.0484699 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0473652 |
| NDRG1 | N-myc downstream regulated 1 | -0.0471891 |
| NEMF | nuclear export mediator factor | -0.046363 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0462991 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.045952 |
| IL1RN | interleukin 1 receptor antagonist | -0.0459481 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0452773 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0452012 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0448561 |
| DENND2C | DENN/MADD domain containing 2C | -0.0440293 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0427338 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0418412 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0410978 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0408494 |
| RIGI | RNA sensor RIG-I | -0.0402791 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0401927 |
| KRT19 | keratin 19, type I | -0.0400462 |
| S100A11 | S100 calcium binding protein A11 | -0.0399249 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0395991 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0392756 |
| CD2AP | CD2-associated protein | -0.039128 |
| PKM | pyruvate kinase, muscle | -0.0390001 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.038943 |
| GLCCI1 | glucocorticoid induced 1 | -0.0387815 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0386288 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0382198 |
| LSAMP | limbic system-associated membrane protein | -0.0380271 |
| USP53 | ubiquitin specific peptidase 53 | -0.0378915 |
| MYO9A | myosin IXA | -0.0377265 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0374504 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0374406 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0374236 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0373331 |
| TXNIP | thioredoxin interacting protein | -0.0366336 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0365447 |
| MUC16 | mucin 16, cell surface associated | -0.0365379 |
| RASAL2 | RAS protein activator like 2 | -0.0364398 |
| SETD5 | SET domain containing 5 | -0.0363559 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.035609 |
| MXD1 | MAX dimerization protein 1 | -0.0353809 |
| RPL35A | ribosomal protein L35a | -0.0352761 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0351926 |
| QKI | QKI, KH domain containing, RNA binding | -0.0350421 |
| SRI | sorcin | -0.0346874 |
| RPL37A | ribosomal protein L37a | -0.0343462 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0342043 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0341993 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0337763 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0337674 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.033527 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0334474 |
| POTEF | POTE ankyrin domain family, member F | -0.0334115 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0332144 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0330253 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0327687 |
| TPD52 | tumor protein D52 | -0.0326613 |
| JMJD1C | jumonji domain containing 1C | -0.0324951 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.032479 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0323346 |
| SLK | STE20-like kinase | -0.032243 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0321895 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0314439 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0314367 |
| PKN2 | protein kinase N2 | -0.0314248 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.031068 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0310032 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0308471 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0308121 |
| SVIL | supervillin | -0.0305367 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0302768 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0301966 |
| MANBA | mannosidase, beta A, lysosomal | -0.0301306 |
| RPL11 | ribosomal protein L11 | -0.0300827 |
| DSG2 | desmoglein 2 | -0.0299064 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0298803 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0297689 |
| PTEN | phosphatase and tensin homolog | -0.0297681 |
| CLIC4 | chloride intracellular channel 4 | -0.0296767 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0295256 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0292985 |
| USP34 | ubiquitin specific peptidase 34 | -0.0291752 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0289914 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0286862 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.02853 |
| HLA-A | major histocompatibility complex, class I, A | -0.0285214 |
