| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.19777 |
| UBC | ubiquitin C | 0.127248 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0885772 |
| AHNAK | AHNAK nucleoprotein | 0.0814878 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0722321 |
| RPS27A | ribosomal protein S27a | 0.0691379 |
| ASPH | aspartate beta-hydroxylase | 0.0611438 |
| MCL1 | myeloid cell leukemia 1 | 0.0603919 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0558417 |
| INTS6 | integrator complex subunit 6 | 0.0493141 |
| ACTN4 | actinin, alpha 4 | 0.0479075 |
| JUN | jun proto-oncogene | 0.0460273 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0454753 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0445966 |
| PTK2 | protein tyrosine kinase 2 | 0.0441918 |
| VIM | vimentin | 0.0423427 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0408917 |
| SMYD3 | SET and MYND domain containing 3 | 0.0408498 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0401434 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0399681 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.039961 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0390661 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.037761 |
| VMP1 | vacuole membrane protein 1 | 0.0376554 |
| SFPQ | splicing factor proline/glutamine-rich | 0.037057 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0369114 |
| NUP98 | nucleoporin 98kDa | 0.035946 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.035389 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0350023 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0334001 |
| ENO1 | enolase 1, (alpha) | 0.0319355 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0313979 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0313619 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.031266 |
| DST | dystonin | 0.0310819 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.030893 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0304967 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0302923 |
| ZNF644 | zinc finger protein 644 | 0.0300905 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.03006 |
| FHL2 | four and a half LIM domains 2 | 0.0298922 |
| MYO1E | myosin IE | 0.029211 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0290098 |
| EXOC4 | exocyst complex component 4 | 0.0285693 |
| RNF220 | ring finger protein 220 | 0.0283196 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0279269 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0272493 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.027159 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0271088 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0270964 |
| APP | amyloid beta (A4) precursor protein | 0.0265849 |
| OGA | O-GlcNAcase | 0.0265459 |
| TRIM66 | tripartite motif containing 66 | 0.0263876 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0262684 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0262007 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0258739 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0255846 |
| FUS | FUS RNA binding protein | 0.0254546 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0250953 |
| SATB2 | SATB homeobox 2 | 0.0250368 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.025034 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.024906 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0248866 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0246504 |
| ZNF780B | zinc finger protein 780B | 0.0245675 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0245389 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0242318 |
| EGR1 | early growth response 1 | 0.0238973 |
| SIK3 | SIK family kinase 3 | 0.0238188 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0237189 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0235687 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.023478 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.023325 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0231797 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0231286 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0229943 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0228771 |
| JMJD1C | jumonji domain containing 1C | 0.0228066 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0227678 |
| WDR27 | WD repeat domain 27 | 0.0227428 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0227393 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0226206 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0224503 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0223891 |
| ATM | ATM serine/threonine kinase | 0.0221077 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0220453 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0220284 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0220131 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0219572 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0219543 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0218749 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0217856 |
| CDK13 | cyclin-dependent kinase 13 | 0.0214846 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0214138 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0213824 |
| USP34 | ubiquitin specific peptidase 34 | 0.0213357 |
| EXOC6B | exocyst complex component 6B | 0.0212386 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0208839 |
| FLNB | filamin B, beta | 0.0207389 |
| FLNA | filamin A, alpha | 0.020638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | -0.235224 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.193778 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.110902 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0995308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989784 |
| PTMA | prothymosin, alpha | -0.0974529 |
| FBL | fibrillarin | -0.0753093 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0694798 |
| RPL35A | ribosomal protein L35a | -0.0682356 |
| RPLP2 | ribosomal protein, large, P2 | -0.0577908 |
| FTL | ferritin, light polypeptide | -0.056183 |
| GOLGA4 | golgin A4 | -0.0560105 |
| RPS2 | ribosomal protein S2 | -0.0545077 |
| RPLP1 | ribosomal protein, large, P1 | -0.0536909 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0524554 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.051208 |
| RPS6 | ribosomal protein S6 | -0.0493896 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0474362 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0473108 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0422371 |
| SFTPA2 | surfactant protein A2 | -0.0414581 |
| PFN1 | profilin 1 | -0.0407396 |
| CENPF | centromere protein F, 350/400kDa | -0.0398223 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0379403 |
| SPAG9 | sperm associated antigen 9 | -0.0357033 |
| YBX1 | Y box binding protein 1 | -0.0356879 |
| MATR3 | matrin 3 | -0.0343699 |
| B2M | beta-2-microglobulin | -0.0336354 |
| FOSL1 | FOS-like antigen 1 | -0.0330925 |
| RPS5 | ribosomal protein S5 | -0.0330864 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0330615 |
| MKI67 | marker of proliferation Ki-67 | -0.0321797 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0314568 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0302262 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0302171 |
| RPS19 | ribosomal protein S19 | -0.0299038 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0292464 |
| DSTN | destrin (actin depolymerizing factor) | -0.0291764 |
| S100A6 | S100 calcium binding protein A6 | -0.0290571 |
| MT2A | metallothionein 2A | -0.0287662 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0283951 |
| TXNRD1 | thioredoxin reductase 1 | -0.0281637 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0278891 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0277827 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0272182 |
| ZFP36 | ZFP36 ring finger protein | -0.0266251 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0263415 |
| HMGA1 | high mobility group AT-hook 1 | -0.0256057 |
| RPS13 | ribosomal protein S13 | -0.0255158 |
| CTSD | cathepsin D | -0.0253388 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0251827 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0251784 |
| AFAP1 | actin filament associated protein 1 | -0.0248762 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0247059 |
| MSN | moesin | -0.0242814 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.024128 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0238165 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236884 |
| RPL12 | ribosomal protein L12 | -0.0236451 |
| SEC24A | SEC24 family member A | -0.0236394 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.023377 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0233689 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0229225 |
| RPS23 | ribosomal protein S23 | -0.0229202 |
| PKM | pyruvate kinase, muscle | -0.0227736 |
| SRP54 | signal recognition particle 54kDa | -0.0227106 |
| RRBP1 | ribosome binding protein 1 | -0.0226405 |
| WASF2 | WAS protein family, member 2 | -0.0221906 |
| NOP58 | NOP58 ribonucleoprotein | -0.0220236 |
| CDCP1 | CUB domain containing protein 1 | -0.0219833 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0218882 |
| TMEM165 | transmembrane protein 165 | -0.0218779 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0217492 |
| TMEM123 | transmembrane protein 123 | -0.0216249 |
| TMSB10 | thymosin beta 10 | -0.0215042 |
| SNX14 | sorting nexin 14 | -0.0210943 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0208283 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | -0.0207263 |
| RPL36 | ribosomal protein L36 | -0.0206182 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0205902 |
| RPL32 | ribosomal protein L32 | -0.020322 |
| TPD52 | tumor protein D52 | -0.0203032 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0202345 |
| RPL11 | ribosomal protein L11 | -0.0201805 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0201618 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0201574 |
| RPL8 | ribosomal protein L8 | -0.0198722 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0198133 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0197966 |
| MTDH | metadherin | -0.0197508 |
| HYOU1 | hypoxia up-regulated 1 | -0.0197441 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.019735 |
| CD109 | CD109 molecule | -0.0195693 |
| RPLP0 | ribosomal protein, large, P0 | -0.0193736 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0192688 |
| RPL21 | ribosomal protein L21 | -0.0191186 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0191113 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0189241 |
| ATP13A3 | ATPase type 13A3 | -0.0188004 |
| DEK | DEK proto-oncogene | -0.0187404 |
