| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.0794751 |
| UBC | ubiquitin C | 0.0680918 |
| AHNAK | AHNAK nucleoprotein | 0.0591786 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0540255 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0538963 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.048556 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0449029 |
| SMAD3 | SMAD family member 3 | 0.0430848 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0416197 |
| ENO1 | enolase 1, (alpha) | 0.0413383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0392224 |
| DOCK5 | dedicator of cytokinesis 5 | 0.038403 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.037074 |
| CD44 | CD44 molecule (Indian blood group) | 0.0368557 |
| JUN | jun proto-oncogene | 0.0354364 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.034803 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0341275 |
| ZNF292 | zinc finger protein 292 | 0.0319304 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.031866 |
| RUNX1 | runt-related transcription factor 1 | 0.0316383 |
| FLNB | filamin B, beta | 0.031373 |
| ARRDC3 | arrestin domain containing 3 | 0.0313226 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0312379 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0311674 |
| CALU | calumenin | 0.0311359 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0306429 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0300466 |
| RPS27A | ribosomal protein S27a | 0.0296947 |
| MLPH | melanophilin | 0.0289459 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0289312 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0276296 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0262183 |
| YEATS2 | YEATS domain containing 2 | 0.0254173 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0252593 |
| PCBP2 | poly(rC) binding protein 2 | 0.0252578 |
| NGLY1 | N-glycanase 1 | 0.0251321 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0250967 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0247331 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0243792 |
| INSIG2 | insulin induced gene 2 | 0.0239731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0237367 |
| AFAP1 | actin filament associated protein 1 | 0.0236988 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0236687 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.023494 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.0233534 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0228938 |
| ATP13A3 | ATPase type 13A3 | 0.0228331 |
| IFI44L | interferon-induced protein 44-like | 0.022503 |
| FAM20C | family with sequence similarity 20, member C | 0.0224654 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0223835 |
| SEC24A | SEC24 family member A | 0.0223022 |
| EMP1 | epithelial membrane protein 1 | 0.0220015 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0219379 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0215156 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0214395 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0213345 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0213324 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0211548 |
| TOP1 | topoisomerase (DNA) I | 0.0210276 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.021023 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0208153 |
| AFDN | afadin, adherens junction formation factor | 0.0206924 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0205747 |
| RNF24 | ring finger protein 24 | 0.0205335 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0205312 |
| COL5A1 | collagen, type V, alpha 1 | 0.0202298 |
| VIRMA | vir like m6A methyltransferase associated | 0.0201034 |
| ZNF148 | zinc finger protein 148 | 0.0199678 |
| RTN4 | reticulon 4 | 0.0199518 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0198236 |
| PTK2 | protein tyrosine kinase 2 | 0.0198232 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0197277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0194763 |
| RBM39 | RNA binding motif protein 39 | 0.0193213 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0193101 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0192809 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0191525 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0191419 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0189998 |
| TPM3 | tropomyosin 3 | 0.0189787 |
| UTRN | utrophin | 0.0189667 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0188947 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0188625 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0188601 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0188471 |
| MYOF | myoferlin | 0.0188279 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0187291 |
| LOX | lysyl oxidase | 0.0185162 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0184147 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0184022 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0183764 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0182547 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0180797 |
| NBAS | neuroblastoma amplified sequence | 0.0180594 |
| ECE1 | endothelin converting enzyme 1 | 0.018046 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0180018 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0179333 |
| ZNF638 | zinc finger protein 638 | 0.0178737 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0176771 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0176528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.202535 |
| HLA-B | major histocompatibility complex, class I, B | -0.180176 |
| FTL | ferritin, light polypeptide | -0.150117 |
| FN1 | fibronectin 1 | -0.139644 |
| B2M | beta-2-microglobulin | -0.130783 |
| COL1A2 | collagen, type I, alpha 2 | -0.116518 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.107994 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0910483 |
| PTMA | prothymosin, alpha | -0.0887988 |
| IER3 | immediate early response 3 | -0.0718731 |
| RPL35A | ribosomal protein L35a | -0.0702675 |
| COL1A1 | collagen, type I, alpha 1 | -0.0700757 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.066646 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0642918 |
| HLA-A | major histocompatibility complex, class I, A | -0.0625856 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0622333 |
| RPS6 | ribosomal protein S6 | -0.0622277 |
| RPLP1 | ribosomal protein, large, P1 | -0.0563119 |
| COL6A2 | collagen, type VI, alpha 2 | -0.056252 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0514857 |
| COL6A1 | collagen, type VI, alpha 1 | -0.051073 |
| RPL31 | ribosomal protein L31 | -0.0505828 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0466512 |
| HLA-C | major histocompatibility complex, class I, C | -0.0456716 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0452609 |
| CDH13 | cadherin 13 | -0.0444859 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0436423 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0424673 |
| PKM | pyruvate kinase, muscle | -0.0411739 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0408925 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0394093 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0387027 |
| CAVIN1 | caveolae associated protein 1 | -0.0379494 |
| S100A9 | S100 calcium binding protein A9 | -0.0363454 |
| ACTG1 | actin gamma 1 | -0.0362893 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0361114 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0350774 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0350441 |
| RPL37A | ribosomal protein L37a | -0.0347873 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0339412 |
| GNAS | GNAS complex locus | -0.0329196 |
| RPS19 | ribosomal protein S19 | -0.0328599 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0327918 |
| EGR1 | early growth response 1 | -0.0326593 |
| S100A6 | S100 calcium binding protein A6 | -0.0322294 |
| TPM4 | tropomyosin 4 | -0.0320469 |
| INSIG1 | insulin induced gene 1 | -0.0313563 |
| FLOT1 | flotillin 1 | -0.0313084 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0303623 |
| CD63 | CD63 molecule | -0.0302968 |
| RPL34 | ribosomal protein L34 | -0.0301388 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.029802 |
| RPLP2 | ribosomal protein, large, P2 | -0.0296058 |
| TMSB10 | thymosin beta 10 | -0.0293947 |
| LOXL2 | lysyl oxidase-like 2 | -0.0289644 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0288951 |
| VCL | vinculin | -0.0285514 |
| S100A10 | S100 calcium binding protein A10 | -0.0277799 |
| CST3 | cystatin C | -0.0275865 |
| RPL23 | ribosomal protein L23 | -0.0273947 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0273301 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0271758 |
| NREP | neuronal regeneration related protein | -0.0271254 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0260112 |
| SQSTM1 | sequestosome 1 | -0.0260025 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0259275 |
| KYNU | kynureninase | -0.0254483 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0254345 |
| SFTPA2 | surfactant protein A2 | -0.025137 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0248469 |
| CTSL | cathepsin L | -0.0247352 |
| COL5A3 | collagen, type V, alpha 3 | -0.0246653 |
| THY1 | Thy-1 cell surface antigen | -0.0244219 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0243624 |
| RPS25 | ribosomal protein S25 | -0.0240087 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0240006 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0237266 |
| FRMD4A | FERM domain containing 4A | -0.0235153 |
| RPL32 | ribosomal protein L32 | -0.0234494 |
| LMNA | lamin A/C | -0.0234169 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.023405 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0233631 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0232299 |
| RPL30 | ribosomal protein L30 | -0.0231366 |
| INTS6 | integrator complex subunit 6 | -0.0228361 |
| ADM | adrenomedullin | -0.0227693 |
| LRRC23 | leucine rich repeat containing 23 | -0.0226683 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0226514 |
| RPS21 | ribosomal protein S21 | -0.0224662 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.02243 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.022385 |
| RPL11 | ribosomal protein L11 | -0.0223804 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0223558 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0221747 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0220993 |
| ITGA1 | integrin, alpha 1 | -0.0217344 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0213742 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0212828 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0212589 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0210521 |
