| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | 0.131602 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.109257 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0851968 |
| RPS27A | ribosomal protein S27a | 0.0846856 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0784845 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0771997 |
| EGFR | epidermal growth factor receptor | 0.0745177 |
| HDAC9 | histone deacetylase 9 | 0.0709519 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0705788 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0686793 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0650667 |
| VCL | vinculin | 0.0641787 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.061278 |
| FOXP1 | forkhead box P1 | 0.0583187 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0547873 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0547606 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0544422 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.054026 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0528704 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0503592 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0502271 |
| LDHA | lactate dehydrogenase A | 0.047926 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0470454 |
| BMP2K | BMP2 inducible kinase | 0.0456088 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0421816 |
| PUM2 | pumilio RNA-binding family member 2 | 0.041826 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0411777 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0409827 |
| PDGFC | platelet derived growth factor C | 0.0399555 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0399118 |
| NPAS2 | neuronal PAS domain protein 2 | 0.039099 |
| SET | SET nuclear proto-oncogene | 0.0382394 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0379644 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0362147 |
| CUL3 | cullin 3 | 0.0356705 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0352603 |
| HDLBP | high density lipoprotein binding protein | 0.0351242 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0350826 |
| XPO6 | exportin 6 | 0.034974 |
| KIF5B | kinesin family member 5B | 0.0346033 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0342753 |
| AMOTL2 | angiomotin like 2 | 0.0342557 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0342323 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0341455 |
| FER1L6 | fer-1-like family member 6 | 0.0338638 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0337702 |
| RBM39 | RNA binding motif protein 39 | 0.0332693 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0329485 |
| NCKAP1 | NCK-associated protein 1 | 0.0319937 |
| SQSTM1 | sequestosome 1 | 0.0319701 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0318535 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0313804 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0310262 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0309822 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0308805 |
| ANKRD17 | ankyrin repeat domain 17 | 0.030844 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0307713 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0307568 |
| PDZD8 | PDZ domain containing 8 | 0.0305639 |
| OGA | O-GlcNAcase | 0.0305461 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0303468 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0302379 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0301924 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0301152 |
| RHEB | Ras homolog enriched in brain | 0.0297956 |
| MEF2A | myocyte enhancer factor 2A | 0.0296639 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0294779 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0293629 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.029334 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0288017 |
| LOXL3 | lysyl oxidase-like 3 | 0.0285955 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0285924 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0283983 |
| YAP1 | Yes-associated protein 1 | 0.0283183 |
| XPOT | exportin, tRNA | 0.02778 |
| VMP1 | vacuole membrane protein 1 | 0.0276785 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.027327 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0273024 |
| MED13L | mediator complex subunit 13-like | 0.0272845 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0271413 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0270122 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.026921 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0268625 |
| ANXA1 | annexin A1 | 0.0268025 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0265787 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0265752 |
| RIGI | RNA sensor RIG-I | 0.0264457 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0264352 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0264273 |
| COPA | coatomer protein complex, subunit alpha | 0.0263053 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0260738 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0254958 |
| MCL1 | myeloid cell leukemia 1 | 0.0254125 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0253922 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0252757 |
| ENO1 | enolase 1, (alpha) | 0.0249108 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0248845 |
| FNIP1 | folliculin interacting protein 1 | 0.0247477 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0247233 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0246784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.122468 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105567 |
| RPS19 | ribosomal protein S19 | -0.100802 |
| PKM | pyruvate kinase, muscle | -0.0904072 |
| RPL35A | ribosomal protein L35a | -0.0844861 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0799011 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0761859 |
| RPLP1 | ribosomal protein, large, P1 | -0.0697193 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0681812 |
| PFN1 | profilin 1 | -0.06521 |
| S100A9 | S100 calcium binding protein A9 | -0.0625908 |
| RPS23 | ribosomal protein S23 | -0.0616365 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0601171 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0570447 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0565607 |
| RPLP0 | ribosomal protein, large, P0 | -0.0554264 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0546598 |
| S100A6 | S100 calcium binding protein A6 | -0.0541389 |
| RPL12 | ribosomal protein L12 | -0.0519473 |
| S100A10 | S100 calcium binding protein A10 | -0.0481356 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.045812 |
| RPS27 | ribosomal protein S27 | -0.0441549 |
| RPL28 | ribosomal protein L28 | -0.0441466 |
| POTEF | POTE ankyrin domain family, member F | -0.0438911 |
| RPL34 | ribosomal protein L34 | -0.0409767 |
| RPL19 | ribosomal protein L19 | -0.0396111 |
| RPL11 | ribosomal protein L11 | -0.0395563 |
| MT2A | metallothionein 2A | -0.0386174 |
| B2M | beta-2-microglobulin | -0.0381446 |
| RPS8 | ribosomal protein S8 | -0.0378216 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0374065 |
| RPL3 | ribosomal protein L3 | -0.0368096 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0360609 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0358534 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0357946 |
| CCND1 | cyclin D1 | -0.0352177 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0346333 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0340645 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0338551 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0334216 |
| RPL21 | ribosomal protein L21 | -0.0331402 |
| S100A4 | S100 calcium binding protein A4 | -0.0328873 |
| NFIA | nuclear factor I/A | -0.0325548 |
| RPS21 | ribosomal protein S21 | -0.0320191 |
| PHIP | pleckstrin homology domain interacting protein | -0.0319618 |
| RPS13 | ribosomal protein S13 | -0.0319114 |
| EZR | ezrin | -0.0315728 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0311599 |
| SBF2 | SET binding factor 2 | -0.0311563 |
| HJURP | Holliday junction recognition protein | -0.0306224 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0304209 |
| RPL5 | ribosomal protein L5 | -0.0298732 |
| RPL36 | ribosomal protein L36 | -0.0298174 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0296305 |
| RPL27A | ribosomal protein L27a | -0.029532 |
| RPS14 | ribosomal protein S14 | -0.0293082 |
| GPHN | gephyrin | -0.0290893 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.028459 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0282366 |
| RPL31 | ribosomal protein L31 | -0.0278237 |
| DSTN | destrin (actin depolymerizing factor) | -0.0277732 |
| FHIT | fragile histidine triad | -0.0273992 |
| NUP58 | nucleoporin 58 | -0.0272176 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0271535 |
| BMP10 | bone morphogenetic protein 10 | -0.0266679 |
| GLI2 | GLI family zinc finger 2 | -0.0263549 |
| ZNF438 | zinc finger protein 438 | -0.0261532 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.026133 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0261263 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0260512 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0257914 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0253572 |
| RPS11 | ribosomal protein S11 | -0.0253431 |
| PRDX2 | peroxiredoxin 2 | -0.0252137 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250951 |
| RUNX1 | runt-related transcription factor 1 | -0.0246322 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244785 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0244617 |
| CENPF | centromere protein F, 350/400kDa | -0.0241643 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0239283 |
| SERF2 | small EDRK-rich factor 2 | -0.0238909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0238125 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0236844 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0234876 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0234228 |
| RPS17 | ribosomal protein S17 | -0.0233869 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0232574 |
| TXNRD1 | thioredoxin reductase 1 | -0.0231451 |
| WASF2 | WAS protein family, member 2 | -0.0227404 |
| HELZ | helicase with zinc finger | -0.0227056 |
| RNF11 | ring finger protein 11 | -0.0226839 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0226518 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0226492 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0224225 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0224201 |
| GSE1 | Gse1 coiled-coil protein | -0.0222247 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0221441 |
| KIF13A | kinesin family member 13A | -0.022141 |
| RSF1 | remodeling and spacing factor 1 | -0.0220112 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0218928 |
