| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.114515 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.110525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.103079 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0810507 |
| HDAC9 | histone deacetylase 9 | 0.0768816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0692363 |
| PDE10A | phosphodiesterase 10A | 0.0560871 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0501708 |
| FMNL2 | formin-like 2 | 0.0481645 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0466907 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.044331 |
| ATXN1 | ataxin 1 | 0.0408594 |
| NAV2 | neuron navigator 2 | 0.0407205 |
| FNIP1 | folliculin interacting protein 1 | 0.0406315 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0402332 |
| MLPH | melanophilin | 0.0400971 |
| INTS6 | integrator complex subunit 6 | 0.0394144 |
| UBC | ubiquitin C | 0.0389143 |
| MYOF | myoferlin | 0.0387762 |
| FLNB | filamin B, beta | 0.0382405 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.038237 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0377314 |
| RPS27A | ribosomal protein S27a | 0.0353709 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0329752 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0327253 |
| TMEM132D | transmembrane protein 132D | 0.0321946 |
| PRELID2 | PRELI domain containing 2 | 0.031931 |
| FLNA | filamin A, alpha | 0.0313958 |
| ASPH | aspartate beta-hydroxylase | 0.0311362 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0311069 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0309873 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0305067 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0300954 |
| COL5A1 | collagen, type V, alpha 1 | 0.0300007 |
| EGFR | epidermal growth factor receptor | 0.0298397 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0298301 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0295585 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0283044 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0272672 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0259846 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0258949 |
| CEP250 | centrosomal protein 250kDa | 0.0249841 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0246524 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0240409 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0237744 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0237162 |
| CDH13 | cadherin 13 | 0.0236858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0235833 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0235762 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0230259 |
| SQSTM1 | sequestosome 1 | 0.0227444 |
| JMJD1C | jumonji domain containing 1C | 0.0226751 |
| MMP12 | matrix metallopeptidase 12 | 0.0225786 |
| SLC39A11 | solute carrier family 39, member 11 | 0.022138 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0220827 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0218421 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0217377 |
| TRIM25 | tripartite motif containing 25 | 0.0215242 |
| RND3 | Rho family GTPase 3 | 0.0214749 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0214419 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0213066 |
| OGA | O-GlcNAcase | 0.0211211 |
| NOTCH2 | notch 2 | 0.0209914 |
| RPS3 | ribosomal protein S3 | 0.0209009 |
| ADM | adrenomedullin | 0.0208909 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0208639 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0207995 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0206813 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0206619 |
| PRKCE | protein kinase C, epsilon | 0.0206225 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0202702 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0199161 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0197602 |
| DTNA | dystrobrevin, alpha | 0.0196925 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0196323 |
| GPC6 | glypican 6 | 0.0195685 |
| DUSP10 | dual specificity phosphatase 10 | 0.0192495 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0192129 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0191829 |
| ARFGEF3 | ARFGEF family member 3 | 0.0188127 |
| BRD2 | bromodomain containing 2 | 0.0186709 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0185866 |
| ZNF638 | zinc finger protein 638 | 0.0184369 |
| TMEM263 | transmembrane protein 263 | 0.018417 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0183419 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0182306 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0181095 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0181079 |
| FAM219A | family with sequence similarity 219, member A | 0.018056 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0178069 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0177052 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0175063 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0173933 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.01739 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0173362 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0172794 |
| RASA3 | RAS p21 protein activator 3 | 0.0172696 |
| CREBRF | CREB3 regulatory factor | 0.0172529 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0171514 |
| SETX | senataxin | 0.0171411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.166546 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132833 |
| FN1 | fibronectin 1 | -0.122028 |
| RPS6 | ribosomal protein S6 | -0.114887 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.112168 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101034 |
| HLA-B | major histocompatibility complex, class I, B | -0.0961587 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0920872 |
| BICC1 | BicC family RNA binding protein 1 | -0.091526 |
| VCL | vinculin | -0.0887623 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0840142 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0824473 |
| GLIS3 | GLIS family zinc finger 3 | -0.0816288 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0769052 |
| MT2A | metallothionein 2A | -0.0732019 |
| FTL | ferritin, light polypeptide | -0.0716071 |
| B2M | beta-2-microglobulin | -0.0691482 |
| PGK1 | phosphoglycerate kinase 1 | -0.0686749 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0634369 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0610788 |
| RPL35A | ribosomal protein L35a | -0.0593982 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0589752 |
| RPLP1 | ribosomal protein, large, P1 | -0.0563614 |
| ANXA2 | annexin A2 | -0.0543426 |
| MKI67 | marker of proliferation Ki-67 | -0.0533721 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0532166 |
| TMSB4X | thymosin beta 4, X-linked | -0.0531214 |
| CD44 | CD44 molecule (Indian blood group) | -0.0514093 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0509461 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0496148 |
| TMSB10 | thymosin beta 10 | -0.049405 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0489258 |
| COL1A2 | collagen, type I, alpha 2 | -0.0458947 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0456838 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0453159 |
| CENPF | centromere protein F, 350/400kDa | -0.0453051 |
| THBS1 | thrombospondin 1 | -0.0447897 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0447842 |
| PTMA | prothymosin, alpha | -0.0439285 |
| SFTPA2 | surfactant protein A2 | -0.0438857 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0438625 |
| TPM4 | tropomyosin 4 | -0.0435796 |
| RPL19 | ribosomal protein L19 | -0.0427695 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.041855 |
| GNAS | GNAS complex locus | -0.0416234 |
| RPS8 | ribosomal protein S8 | -0.0406462 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0405604 |
| TUBB | tubulin, beta class I | -0.04054 |
| RPS19 | ribosomal protein S19 | -0.0390082 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0377238 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0361093 |
| MAP4 | microtubule-associated protein 4 | -0.0351717 |
| RPL36A | ribosomal protein L36a | -0.0344521 |
| HLA-A | major histocompatibility complex, class I, A | -0.0342848 |
| ACTG1 | actin gamma 1 | -0.0342561 |
| RPL35 | ribosomal protein L35 | -0.033571 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0333128 |
| VCAN | versican | -0.033123 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0331012 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0326329 |
| TXNIP | thioredoxin interacting protein | -0.0324961 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0322653 |
| CDCP1 | CUB domain containing protein 1 | -0.0319256 |
| EGR1 | early growth response 1 | -0.031893 |
| S100A9 | S100 calcium binding protein A9 | -0.0313888 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0313122 |
| RPL12 | ribosomal protein L12 | -0.0310431 |
| RRBP1 | ribosome binding protein 1 | -0.0309245 |
| NCOA7 | nuclear receptor coactivator 7 | -0.030755 |
| KLF6 | Kruppel-like factor 6 | -0.030639 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303127 |
| HLA-C | major histocompatibility complex, class I, C | -0.0301007 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0298293 |
| RPL34 | ribosomal protein L34 | -0.0295434 |
| RPLP2 | ribosomal protein, large, P2 | -0.0295028 |
| RPLP0 | ribosomal protein, large, P0 | -0.0292746 |
| IER3 | immediate early response 3 | -0.0292333 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.029222 |
| PHF21A | PHD finger protein 21A | -0.0286648 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.028214 |
| RPL36 | ribosomal protein L36 | -0.0281015 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0280954 |
| RPL32 | ribosomal protein L32 | -0.028085 |
| PALLD | palladin, cytoskeletal associated protein | -0.0279954 |
| RPS23 | ribosomal protein S23 | -0.0278927 |
| ANLN | anillin, actin binding protein | -0.0275098 |
| SRGN | serglycin | -0.0271321 |
| TNNC1 | troponin C type 1 (slow) | -0.0270161 |
| KIF4A | kinesin family member 4A | -0.0269686 |
| TMEM41B | transmembrane protein 41B | -0.0268328 |
| TXNRD1 | thioredoxin reductase 1 | -0.0267925 |
| RPS2 | ribosomal protein S2 | -0.0266377 |
| QKI | QKI, KH domain containing, RNA binding | -0.0264827 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0261818 |
| RPL26 | ribosomal protein L26 | -0.026082 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0260001 |
| RAD21 | RAD21 homolog (S. pombe) | -0.025861 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0257736 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0257362 |
| RPL8 | ribosomal protein L8 | -0.025729 |
