| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | 0.191575 |
| RPS27A | ribosomal protein S27a | 0.155164 |
| TMSB10 | thymosin beta 10 | 0.100622 |
| IFRD1 | interferon-related developmental regulator 1 | 0.095496 |
| VCL | vinculin | 0.0857815 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0812653 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0802104 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0783837 |
| RPS3 | ribosomal protein S3 | 0.0772493 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0753491 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0742213 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0741476 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0699332 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0692179 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0654764 |
| CALU | calumenin | 0.0647773 |
| RPL37A | ribosomal protein L37a | 0.0636785 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0636489 |
| PCBP2 | poly(rC) binding protein 2 | 0.0633291 |
| AHNAK | AHNAK nucleoprotein | 0.0563582 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0554011 |
| INTS6 | integrator complex subunit 6 | 0.0550722 |
| EZR | ezrin | 0.0541586 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0537861 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0526243 |
| SMAD3 | SMAD family member 3 | 0.0515864 |
| MYO1E | myosin IE | 0.0512367 |
| SET | SET nuclear proto-oncogene | 0.0507646 |
| NEBL | nebulette | 0.050081 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0491958 |
| RPS12 | ribosomal protein S12 | 0.0483386 |
| AMOTL2 | angiomotin like 2 | 0.0477271 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.047444 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0466181 |
| JUN | jun proto-oncogene | 0.0462274 |
| FAM107B | family with sequence similarity 107, member B | 0.0461521 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0455517 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0453554 |
| RAB7A | RAB7A, member RAS oncogene family | 0.044335 |
| YAP1 | Yes-associated protein 1 | 0.0442637 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0440717 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0429895 |
| ACTG1 | actin gamma 1 | 0.042428 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0420074 |
| CDK13 | cyclin-dependent kinase 13 | 0.0417725 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0415874 |
| CANX | calnexin | 0.0413912 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0406847 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0391985 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0387641 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0381643 |
| TOP1 | topoisomerase (DNA) I | 0.0378199 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0378132 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.037549 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0366588 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0361461 |
| ACTN4 | actinin, alpha 4 | 0.0354352 |
| CUL3 | cullin 3 | 0.0354215 |
| PTK2 | protein tyrosine kinase 2 | 0.0345492 |
| TUFT1 | tuftelin 1 | 0.0344811 |
| CALR | calreticulin | 0.0337123 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0336357 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0335196 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.033186 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0322885 |
| USP34 | ubiquitin specific peptidase 34 | 0.0322619 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.032231 |
| FBXO11 | F-box protein 11 | 0.0320147 |
| SIK3 | SIK family kinase 3 | 0.0319348 |
| CCNY | cyclin Y | 0.031452 |
| FLNA | filamin A, alpha | 0.0313892 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0312118 |
| DSCAM | Down syndrome cell adhesion molecule | 0.031038 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0310115 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0307269 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304492 |
| SERINC3 | serine incorporator 3 | 0.0302433 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029984 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0298917 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0298904 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0295871 |
| PTEN | phosphatase and tensin homolog | 0.029537 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0295354 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0288518 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.028801 |
| HDLBP | high density lipoprotein binding protein | 0.0287073 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0286944 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0286267 |
| AFDN | afadin, adherens junction formation factor | 0.0285453 |
| MCL1 | myeloid cell leukemia 1 | 0.0282686 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.028247 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0280288 |
| FLNB | filamin B, beta | 0.0277681 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0277493 |
| CTBP2 | C-terminal binding protein 2 | 0.0277342 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0276314 |
| ACTN1 | actinin, alpha 1 | 0.0274469 |
| DOCK5 | dedicator of cytokinesis 5 | 0.027275 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0272405 |
| RPS13 | ribosomal protein S13 | 0.0271872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.112957 |
| RPL35A | ribosomal protein L35a | -0.0791977 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0783031 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0761942 |
| KRT18 | keratin 18, type I | -0.0748649 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0735999 |
| RPS6 | ribosomal protein S6 | -0.0726372 |
| KRT8 | keratin 8, type II | -0.0654881 |
| H1-0 | H1.0 linker histone | -0.0583571 |
| PTMA | prothymosin, alpha | -0.0539091 |
| MKI67 | marker of proliferation Ki-67 | -0.0525733 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0510365 |
| B2M | beta-2-microglobulin | -0.0490918 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0486899 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0471026 |
| CST3 | cystatin C | -0.0463544 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0459755 |
| TMSB4X | thymosin beta 4, X-linked | -0.0435097 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0430392 |
| CCND1 | cyclin D1 | -0.0410147 |
| RPS21 | ribosomal protein S21 | -0.0407344 |
| TMEM123 | transmembrane protein 123 | -0.0407119 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0395011 |
| TXNIP | thioredoxin interacting protein | -0.037899 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0364709 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0355671 |
| RPLP1 | ribosomal protein, large, P1 | -0.0342261 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0336841 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0322061 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0321386 |
| CBX3 | chromobox homolog 3 | -0.0320183 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0316584 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0312589 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0307223 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303556 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0300397 |
| MATR3 | matrin 3 | -0.0291841 |
| ZNF292 | zinc finger protein 292 | -0.028606 |
| KRT19 | keratin 19, type I | -0.028527 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0283674 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0276827 |
| ZNRF3 | zinc and ring finger 3 | -0.0275749 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0270329 |
| ITGB4 | integrin, beta 4 | -0.0270179 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0269806 |
| S100A6 | S100 calcium binding protein A6 | -0.0267224 |
| BSG | basigin (Ok blood group) | -0.0263561 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0262899 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0255244 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0250895 |
| CDCP1 | CUB domain containing protein 1 | -0.0245619 |
| FAM3C | family with sequence similarity 3, member C | -0.024182 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.024062 |
| PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta | -0.0234254 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0233064 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0231699 |
| GPSM2 | G-protein signaling modulator 2 | -0.023161 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0228807 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0226352 |
| GNAS | GNAS complex locus | -0.0226238 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0225138 |
| SNRK | SNF related kinase | -0.0224292 |
| CENPF | centromere protein F, 350/400kDa | -0.0223315 |
| USP3 | ubiquitin specific peptidase 3 | -0.0221223 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0218065 |
| RPL12 | ribosomal protein L12 | -0.0217028 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0215509 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0215182 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.021472 |
| EHF | ets homologous factor | -0.0214526 |
| PGK1 | phosphoglycerate kinase 1 | -0.0211316 |
| RPS11 | ribosomal protein S11 | -0.021091 |
| SETD5 | SET domain containing 5 | -0.0210733 |
| CD2AP | CD2-associated protein | -0.0208643 |
| HEPHL1 | hephaestin-like 1 | -0.0208389 |
| KLF10 | Kruppel-like factor 10 | -0.0206912 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.0206209 |
| APCDD1 | adenomatosis polyposis coli down-regulated 1 | -0.0205454 |
| MXD1 | MAX dimerization protein 1 | -0.0205176 |
| EDAR | ectodysplasin A receptor | -0.0203033 |
| VSNL1 | visinin-like 1 | -0.0202815 |
| SYK | spleen tyrosine kinase | -0.0202729 |
| SCG2 | secretogranin II | -0.0199715 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0196684 |
| ZFR | zinc finger RNA binding protein | -0.0194054 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0192263 |
| PERP | PERP, TP53 apoptosis effector | -0.0192203 |
| CPLX2 | complexin 2 | -0.0191538 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0190426 |
| ADAR | adenosine deaminase, RNA-specific | -0.0189424 |
| TUBB | tubulin, beta class I | -0.0188385 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0187846 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0185172 |
| RNF43 | ring finger protein 43 | -0.0184479 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0181509 |
| OGFR | opioid growth factor receptor | -0.0180956 |
| PKP4 | plakophilin 4 | -0.018093 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0177626 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.017472 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0173886 |
