| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMC2 | laminin, gamma 2 | 0.102285 |
| EMP1 | epithelial membrane protein 1 | 0.0949874 |
| UBC | ubiquitin C | 0.0917405 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0885935 |
| RPS27A | ribosomal protein S27a | 0.0808879 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.074416 |
| HMGA2 | high mobility group AT-hook 2 | 0.0599615 |
| AREG | amphiregulin | 0.0592653 |
| ATXN1 | ataxin 1 | 0.0576952 |
| LMO7 | LIM domain 7 | 0.0569332 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0519361 |
| FHL2 | four and a half LIM domains 2 | 0.0496474 |
| EZR | ezrin | 0.0490349 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0415149 |
| SNX9 | sorting nexin 9 | 0.0414234 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0412124 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0411671 |
| ACTG1 | actin gamma 1 | 0.0385411 |
| AHNAK | AHNAK nucleoprotein | 0.0382485 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0335552 |
| TPM4 | tropomyosin 4 | 0.0326825 |
| NUP50 | nucleoporin 50kDa | 0.03191 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0301296 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0300692 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0300523 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0299696 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0293451 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283488 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.027742 |
| CDCP1 | CUB domain containing protein 1 | 0.0276639 |
| ENO1 | enolase 1, (alpha) | 0.0275536 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0272643 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0272161 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0269201 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0268641 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0268145 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0267723 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0265832 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0262293 |
| ARRDC3 | arrestin domain containing 3 | 0.0259472 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0257388 |
| CD44 | CD44 molecule (Indian blood group) | 0.0256257 |
| ANXA1 | annexin A1 | 0.0255639 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0246947 |
| EXOC4 | exocyst complex component 4 | 0.023762 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0237582 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0235092 |
| BCL2L1 | BCL2-like 1 | 0.02305 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0228618 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0226634 |
| JUN | jun proto-oncogene | 0.022397 |
| FAT1 | FAT atypical cadherin 1 | 0.0220877 |
| CTSB | cathepsin B | 0.022043 |
| SET | SET nuclear proto-oncogene | 0.0217174 |
| RNF43 | ring finger protein 43 | 0.0216732 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0209402 |
| PCBP2 | poly(rC) binding protein 2 | 0.0208383 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0205811 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0203619 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0201357 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0199437 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0195774 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0194611 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0193387 |
| RTN4 | reticulon 4 | 0.0193374 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0192118 |
| PERP | PERP, TP53 apoptosis effector | 0.0190926 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0187744 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0187564 |
| ASPH | aspartate beta-hydroxylase | 0.018694 |
| ITGA6 | integrin, alpha 6 | 0.0186837 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0186352 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.0186121 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0184521 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0183818 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0183165 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0182887 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0182739 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0179249 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0177553 |
| FERMT1 | fermitin family member 1 | 0.0177325 |
| PHF14 | PHD finger protein 14 | 0.0176886 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0175229 |
| DUSP6 | dual specificity phosphatase 6 | 0.0174445 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0174205 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0172931 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0172138 |
| WASHC4 | WASH complex subunit 4 | 0.0170966 |
| ARRDC4 | arrestin domain containing 4 | 0.0167093 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0166963 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0165834 |
| TRIB1 | tribbles pseudokinase 1 | 0.0163903 |
| SGMS2 | sphingomyelin synthase 2 | 0.0163666 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0161596 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0159847 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0159447 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0159371 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0159353 |
| USP6NL | USP6 N-terminal like | 0.0159345 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.0159224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.162793 |
| RPS6 | ribosomal protein S6 | -0.158869 |
| RPL35A | ribosomal protein L35a | -0.114565 |
| EGR1 | early growth response 1 | -0.0836333 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0618074 |
| RPL34 | ribosomal protein L34 | -0.0605914 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0516786 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0484114 |
| RPS19 | ribosomal protein S19 | -0.0464326 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0461255 |
| RPLP1 | ribosomal protein, large, P1 | -0.0461138 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0447582 |
| RCOR1 | REST corepressor 1 | -0.0444211 |
| MKI67 | marker of proliferation Ki-67 | -0.0435712 |
| KRT18 | keratin 18, type I | -0.0435468 |
| RPS2 | ribosomal protein S2 | -0.0424283 |
| RPS24 | ribosomal protein S24 | -0.0418089 |
| PARD3 | par-3 family cell polarity regulator | -0.0416925 |
| RPLP2 | ribosomal protein, large, P2 | -0.0415149 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0398744 |
| CENPF | centromere protein F, 350/400kDa | -0.0396982 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0396561 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0391039 |
| RPL11 | ribosomal protein L11 | -0.0382268 |
| RPS13 | ribosomal protein S13 | -0.0380802 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0373433 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0369494 |
| RPL31 | ribosomal protein L31 | -0.0369111 |
| LMNA | lamin A/C | -0.0365167 |
| RPS11 | ribosomal protein S11 | -0.0365139 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0359863 |
| COG5 | component of oligomeric golgi complex 5 | -0.0357845 |
| CUX1 | cut-like homeobox 1 | -0.0352198 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0350036 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.034272 |
| RPL19 | ribosomal protein L19 | -0.032653 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0322263 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0320858 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0317618 |
| HDAC2 | histone deacetylase 2 | -0.0312016 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0309935 |
| IER3 | immediate early response 3 | -0.0305721 |
| BRD2 | bromodomain containing 2 | -0.0300994 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0297085 |
| PKM | pyruvate kinase, muscle | -0.0295092 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0284225 |
| RPL32 | ribosomal protein L32 | -0.0276618 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0275963 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0274034 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0273899 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.027131 |
| RPL5 | ribosomal protein L5 | -0.0269422 |
| RPS8 | ribosomal protein S8 | -0.0261909 |
| MAP4 | microtubule-associated protein 4 | -0.0261668 |
| RPS14 | ribosomal protein S14 | -0.0261457 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0258395 |
| RPS21 | ribosomal protein S21 | -0.0254357 |
| RPL36 | ribosomal protein L36 | -0.0254203 |
| RPL3 | ribosomal protein L3 | -0.0252212 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0250506 |
| FOXK1 | forkhead box K1 | -0.0250193 |
| MATR3 | matrin 3 | -0.0247261 |
| RPS25 | ribosomal protein S25 | -0.0243552 |
| RPL27A | ribosomal protein L27a | -0.024291 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0242259 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0240357 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0237106 |
| CBX3 | chromobox homolog 3 | -0.0236028 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0236009 |
| SBF2 | SET binding factor 2 | -0.023508 |
| FLOT1 | flotillin 1 | -0.0234306 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.023269 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0231917 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0231034 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0230518 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0229402 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0225683 |
| BPTF | bromodomain PHD finger transcription factor | -0.0224529 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0223673 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0222767 |
| RREB1 | ras responsive element binding protein 1 | -0.0220836 |
| ANK2 | ankyrin 2, neuronal | -0.0220708 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0219774 |
| RBM39 | RNA binding motif protein 39 | -0.021884 |
| TUBB | tubulin, beta class I | -0.0215643 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.021406 |
| ABR | active BCR-related | -0.0211595 |
| RPS15 | ribosomal protein S15 | -0.0211141 |
| SIK3 | SIK family kinase 3 | -0.0210221 |
| VSNL1 | visinin-like 1 | -0.0208775 |
| HLA-A | major histocompatibility complex, class I, A | -0.020389 |
| PFN1 | profilin 1 | -0.0203667 |
| KRT8 | keratin 8, type II | -0.0202775 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0200993 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0200596 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0198867 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0197813 |
| YLPM1 | YLP motif containing 1 | -0.0196384 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0194819 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0193264 |
