| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.154126 |
| EZR | ezrin | 0.1319 |
| TMSB10 | thymosin beta 10 | 0.0822432 |
| ANXA2 | annexin A2 | 0.0797596 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0755171 |
| KRT18 | keratin 18, type I | 0.0647593 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0608755 |
| EMP1 | epithelial membrane protein 1 | 0.0594551 |
| SPATA13 | spermatogenesis associated 13 | 0.0571326 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0569685 |
| ITGA6 | integrin, alpha 6 | 0.0561629 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0503528 |
| ACTN1 | actinin, alpha 1 | 0.0501686 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0497106 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0496762 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0484756 |
| CDH13 | cadherin 13 | 0.0463113 |
| FLNB | filamin B, beta | 0.0451699 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0446227 |
| DUSP6 | dual specificity phosphatase 6 | 0.0444785 |
| AHNAK | AHNAK nucleoprotein | 0.0432832 |
| ASPH | aspartate beta-hydroxylase | 0.0424566 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0422566 |
| COBL | cordon-bleu WH2 repeat protein | 0.0419158 |
| CCND1 | cyclin D1 | 0.0415776 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0393023 |
| NAV2 | neuron navigator 2 | 0.0391365 |
| VCL | vinculin | 0.0381151 |
| MT2A | metallothionein 2A | 0.0374873 |
| ENO1 | enolase 1, (alpha) | 0.0373214 |
| NDRG1 | N-myc downstream regulated 1 | 0.0364834 |
| MYOF | myoferlin | 0.0362099 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0359575 |
| JUN | jun proto-oncogene | 0.0359338 |
| EXOC4 | exocyst complex component 4 | 0.034815 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0345866 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0341323 |
| LAMA4 | laminin, alpha 4 | 0.0338689 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.033791 |
| CD44 | CD44 molecule (Indian blood group) | 0.0335 |
| ITGB4 | integrin, beta 4 | 0.033474 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0317136 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0313447 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0309906 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0304461 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0304437 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0304334 |
| PLEC | plectin | 0.0300501 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0292383 |
| TPM4 | tropomyosin 4 | 0.0290688 |
| H1-0 | H1.0 linker histone | 0.0289862 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0289046 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0286535 |
| ANXA3 | annexin A3 | 0.0284879 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0280277 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277145 |
| ACTG1 | actin gamma 1 | 0.0270914 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0269979 |
| LMNA | lamin A/C | 0.026909 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0266858 |
| ACTN4 | actinin, alpha 4 | 0.0265812 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0263309 |
| SQSTM1 | sequestosome 1 | 0.0260988 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0258139 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0240536 |
| NEBL | nebulette | 0.0237223 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0235369 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0235173 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0234084 |
| WDR43 | WD repeat domain 43 | 0.0233559 |
| MT1X | metallothionein 1X | 0.023254 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0232171 |
| SERINC5 | serine incorporator 5 | 0.0227558 |
| MYO1E | myosin IE | 0.0226263 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0222998 |
| APP | amyloid beta (A4) precursor protein | 0.022153 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0219481 |
| GSPT1 | G1 to S phase transition 1 | 0.0219326 |
| SET | SET nuclear proto-oncogene | 0.0217507 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0213332 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0212516 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0212113 |
| YBX3 | Y box binding protein 3 | 0.0209345 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0207644 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0205508 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0205213 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0203135 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0201564 |
| KLF6 | Kruppel-like factor 6 | 0.0201505 |
| EPHB2 | EPH receptor B2 | 0.0201477 |
| SDC4 | syndecan 4 | 0.0198176 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0196695 |
| FTL | ferritin, light polypeptide | 0.0196206 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0196175 |
| FOSL1 | FOS-like antigen 1 | 0.01942 |
| MYADM | myeloid-associated differentiation marker | 0.0189698 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.018816 |
| HUNK | hormonally up-regulated Neu-associated kinase | 0.0185885 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit | 0.0185364 |
| CTBP2 | C-terminal binding protein 2 | 0.0185322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138047 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.108109 |
| SYT1 | synaptotagmin I | -0.0867859 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0750227 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0699903 |
| PCBP2 | poly(rC) binding protein 2 | -0.0693575 |
| OXR1 | oxidation resistance 1 | -0.068257 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0650473 |
| DIAPH3 | diaphanous-related formin 3 | -0.0577037 |
| UBC | ubiquitin C | -0.0547424 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0521156 |
| VGLL4 | vestigial-like family member 4 | -0.0518146 |
| OGA | O-GlcNAcase | -0.0505323 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0478278 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.045665 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0448487 |
| RBM39 | RNA binding motif protein 39 | -0.0446756 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0439401 |
| RPL35A | ribosomal protein L35a | -0.0436003 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0432326 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0425456 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0409535 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.040572 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0398704 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0392545 |
| RPS23 | ribosomal protein S23 | -0.0387793 |
| PTEN | phosphatase and tensin homolog | -0.0386314 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0384856 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0378578 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0372066 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0367589 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0366532 |
| SBF2 | SET binding factor 2 | -0.0365908 |
| UTRN | utrophin | -0.0362026 |
| MKI67 | marker of proliferation Ki-67 | -0.0361496 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0358843 |
| AOPEP | aminopeptidase O (putative) | -0.0356555 |
| NKTR | natural killer cell triggering receptor | -0.0355617 |
| RPLP2 | ribosomal protein, large, P2 | -0.0354078 |
| JMJD1C | jumonji domain containing 1C | -0.0352778 |
| ETNK1 | ethanolamine kinase 1 | -0.0351435 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0349335 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.034888 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0348333 |
| PROX1 | prospero homeobox 1 | -0.0346209 |
| TNS3 | tensin 3 | -0.0341301 |
| CCDC82 | coiled-coil domain containing 82 | -0.033755 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0331989 |
| XPO1 | exportin 1 | -0.0331083 |
| RNF43 | ring finger protein 43 | -0.0330562 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0326322 |
| LRP6 | low density lipoprotein receptor-related protein 6 | -0.0322661 |
| TXNIP | thioredoxin interacting protein | -0.0315258 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0314153 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0310112 |
| THOC2 | THO complex 2 | -0.0308635 |
| VMP1 | vacuole membrane protein 1 | -0.0306104 |
| SESN3 | sestrin 3 | -0.0305855 |
| RUNX1 | runt-related transcription factor 1 | -0.030493 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0304275 |
| SETD5 | SET domain containing 5 | -0.0304053 |
| RBM33 | RNA binding motif protein 33 | -0.0303675 |
| ZNF638 | zinc finger protein 638 | -0.0301878 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.03013 |
| FOXP1 | forkhead box P1 | -0.0300979 |
| RPS13 | ribosomal protein S13 | -0.0298169 |
| ANLN | anillin, actin binding protein | -0.0295836 |
| NF1 | neurofibromin 1 | -0.0292034 |
| PLPP3 | phospholipid phosphatase 3 | -0.0291044 |
| RPL7A | ribosomal protein L7a | -0.0289656 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0288239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0285386 |
| PDE8A | phosphodiesterase 8A | -0.0284766 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0282413 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0281328 |
| NONO | non-POU domain containing, octamer-binding | -0.0281066 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0280906 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0280498 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0278623 |
| HDAC8 | histone deacetylase 8 | -0.0277034 |
| ZNF292 | zinc finger protein 292 | -0.0276526 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | -0.0275809 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0275222 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0274872 |
| ATXN1 | ataxin 1 | -0.0272386 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0271294 |
| RPL9 | ribosomal protein L9 | -0.0271194 |
| RPL11 | ribosomal protein L11 | -0.0270021 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0269411 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0267893 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.026715 |
| SP3 | Sp3 transcription factor | -0.0266986 |
| RSF1 | remodeling and spacing factor 1 | -0.0266728 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0265722 |
| CDK8 | cyclin-dependent kinase 8 | -0.0262178 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0261727 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0261678 |
| MALT1 | MALT1 paracaspase | -0.0261513 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0261356 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | -0.0261266 |
