| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ropivacaine (hydrochloride monohydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ropivacaine (hydrochloride monohydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.14344 |
| MYO10 | myosin X | 0.110042 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0932241 |
| EMP1 | epithelial membrane protein 1 | 0.0840837 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0826022 |
| MMP1 | matrix metallopeptidase 1 | 0.0823163 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0811694 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0648692 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0612762 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0596609 |
| NAV1 | neuron navigator 1 | 0.0594511 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0586549 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0547944 |
| INHBA | inhibin, beta A | 0.0539726 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0486159 |
| EGFR | epidermal growth factor receptor | 0.0447695 |
| FMNL2 | formin-like 2 | 0.0430216 |
| HLA-B | major histocompatibility complex, class I, B | 0.0410572 |
| AHNAK | AHNAK nucleoprotein | 0.0408434 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0363484 |
| KIAA1549L | KIAA1549-like | 0.0357862 |
| CLMP | CXADR-like membrane protein | 0.0354497 |
| DIAPH2 | diaphanous-related formin 2 | 0.0353985 |
| OXR1 | oxidation resistance 1 | 0.0347436 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0331043 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0328736 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0325253 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.031552 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0311773 |
| CDH13 | cadherin 13 | 0.0302546 |
| COL1A1 | collagen, type I, alpha 1 | 0.0295334 |
| NPTX1 | neuronal pentraxin I | 0.0293293 |
| FOXP1 | forkhead box P1 | 0.0291348 |
| COL6A2 | collagen, type VI, alpha 2 | 0.028938 |
| TMSB10 | thymosin beta 10 | 0.0285938 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0279295 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0278832 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0274286 |
| NCKAP5 | NCK-associated protein 5 | 0.0268531 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.025738 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0255809 |
| VCL | vinculin | 0.0249789 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0246165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0235115 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0230997 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0227203 |
| MYO1E | myosin IE | 0.0226343 |
| RAI14 | retinoic acid induced 14 | 0.0221542 |
| RPS27A | ribosomal protein S27a | 0.0216291 |
| CA12 | carbonic anhydrase XII | 0.0214833 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0212669 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0208749 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0206997 |
| FRMD4A | FERM domain containing 4A | 0.0205854 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0204871 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0200482 |
| SYNJ2 | synaptojanin 2 | 0.0200002 |
| MYADM | myeloid-associated differentiation marker | 0.0196537 |
| PRRX1 | paired related homeobox 1 | 0.0193376 |
| DNER | delta/notch-like EGF repeat containing | 0.0191608 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0189324 |
| GLIS3 | GLIS family zinc finger 3 | 0.0187919 |
| CAVIN1 | caveolae associated protein 1 | 0.0187833 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0186053 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0182661 |
| KITLG | KIT ligand | 0.0180748 |
| EXOC4 | exocyst complex component 4 | 0.0180243 |
| WDR1 | WD repeat domain 1 | 0.0178169 |
| COL5A1 | collagen, type V, alpha 1 | 0.0176947 |
| RASA3 | RAS p21 protein activator 3 | 0.0173517 |
| ASPH | aspartate beta-hydroxylase | 0.0173516 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0172462 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0169449 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0168724 |
| FRMD6 | FERM domain containing 6 | 0.0168489 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0168111 |
| MYO9B | myosin IXB | 0.0166013 |
| MYO9A | myosin IXA | 0.0165921 |
| FBN1 | fibrillin 1 | 0.0163304 |
| MCL1 | myeloid cell leukemia 1 | 0.0162605 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0161543 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0161195 |
| MYO1D | myosin ID | 0.0159764 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0157837 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0157437 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0155347 |
| MSN | moesin | 0.015347 |
| MT2A | metallothionein 2A | 0.01531 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0153035 |
| TMEM165 | transmembrane protein 165 | 0.0152386 |
| MTSS1 | metastasis suppressor 1 | 0.0149185 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0149122 |
| EHBP1 | EH domain binding protein 1 | 0.0148728 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0147728 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.014742 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0146856 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0146826 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0146633 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0146476 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0145329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251214 |
| VIM | vimentin | -0.162603 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0932367 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0842016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0777286 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0751944 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0724642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0591347 |
| COL1A2 | collagen, type I, alpha 2 | -0.0591211 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0564182 |
| PKM | pyruvate kinase, muscle | -0.0535371 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0522683 |
| FTL | ferritin, light polypeptide | -0.0517425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0471075 |
| FAM13A | family with sequence similarity 13, member A | -0.0461412 |
| PTMA | prothymosin, alpha | -0.0450234 |
| LDHA | lactate dehydrogenase A | -0.0425206 |
| FN1 | fibronectin 1 | -0.0423143 |
| NDRG1 | N-myc downstream regulated 1 | -0.0418876 |
| SPAG9 | sperm associated antigen 9 | -0.0414521 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0408616 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0405297 |
| DST | dystonin | -0.0402083 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396489 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0389565 |
| RPS6 | ribosomal protein S6 | -0.0387253 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0382009 |
| GOLGA4 | golgin A4 | -0.0368536 |
| B2M | beta-2-microglobulin | -0.0367279 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0365162 |
| RPL23 | ribosomal protein L23 | -0.0364508 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0353587 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0350311 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0338809 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0333732 |
| ADM | adrenomedullin | -0.033328 |
| PCBP2 | poly(rC) binding protein 2 | -0.032738 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0321502 |
| NBAS | neuroblastoma amplified sequence | -0.0311305 |
| RPLP1 | ribosomal protein, large, P1 | -0.0309398 |
| LOX | lysyl oxidase | -0.0307417 |
| NUP58 | nucleoporin 58 | -0.0307255 |
| CALU | calumenin | -0.0307149 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0305996 |
| ZNF292 | zinc finger protein 292 | -0.0302007 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0300627 |
| HMGB2 | high mobility group box 2 | -0.0298019 |
| USP3 | ubiquitin specific peptidase 3 | -0.0289065 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0284228 |
| ANXA2 | annexin A2 | -0.0283832 |
| RUNX1 | runt-related transcription factor 1 | -0.0281047 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.027886 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0278837 |
| SEC24D | SEC24 family member D | -0.027737 |
| COL4A1 | collagen, type IV, alpha 1 | -0.0275754 |
| OGA | O-GlcNAcase | -0.0275709 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0271683 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0268823 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0259862 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0259225 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0258385 |
| HELZ | helicase with zinc finger | -0.0257895 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0257776 |
| MAP1B | microtubule-associated protein 1B | -0.0254656 |
| CLTC | clathrin, heavy chain (Hc) | -0.0251099 |
| SRGN | serglycin | -0.025092 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0250178 |
| MORF4L2 | mortality factor 4 like 2 | -0.0249669 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0247477 |
| MYOF | myoferlin | -0.0245902 |
| SQSTM1 | sequestosome 1 | -0.0240341 |
| CLINT1 | clathrin interactor 1 | -0.0238727 |
| COPA | coatomer protein complex, subunit alpha | -0.0237095 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.023635 |
| CORO1C | coronin, actin binding protein, 1C | -0.023512 |
| TXNIP | thioredoxin interacting protein | -0.0233038 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0232189 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0227739 |
| PFN1 | profilin 1 | -0.0225985 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0225161 |
| RPL19 | ribosomal protein L19 | -0.0221576 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0220725 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0220399 |
| SUCO | SUN domain containing ossification factor | -0.02168 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0216763 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0215025 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0212228 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0208716 |
| COL3A1 | collagen, type III, alpha 1 | -0.0207285 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0207253 |
| CENPF | centromere protein F, 350/400kDa | -0.0206384 |
| TPI1 | triosephosphate isomerase 1 | -0.0199841 |
| VMP1 | vacuole membrane protein 1 | -0.0197486 |
| YBX1 | Y box binding protein 1 | -0.0196188 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0193113 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0189551 |
| RPL11 | ribosomal protein L11 | -0.018842 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0186655 |
| MSI2 | musashi RNA-binding protein 2 | -0.0186267 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0185807 |
