Rosacea Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

288 genes co-occuring with the disease Rosacea in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CAMP cathelicidin antimicrobial peptide 3.279
KLK5 kallikrein-related peptidase 5 3.208
TLR2 toll-like receptor 2 2.571
MRGPRX2 MAS-related GPR, member X2 2.517
TAC1 tachykinin, precursor 1 2.472
IL1B interleukin 1, beta 2.398
TNF tumor necrosis factor 2.357
CXCL8 chemokine (C-X-C motif) ligand 8 2.33
DEFB103A defensin, beta 103A 2.298
DEFB4A defensin, beta 4A 2.289
FLG filaggrin 2.289
FLG2 filaggrin family member 2 2.276
IL17A interleukin 17A 2.273
IL6 interleukin 6 2.267
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.235
IL1A interleukin 1, alpha 2.232
MMP9 matrix metallopeptidase 9 2.223
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 2.193
RNASE7 ribonuclease, RNase A family, 7 2.16
S100A7 S100 calcium binding protein A7 2.146
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.093
CD4 CD4 molecule 2.077
DCD dermcidin 2.075
ADAMDEC1 ADAM-like, decysin 1 2.065
KLK7 kallikrein-related peptidase 7 2.047
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.038
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.036
IL4 interleukin 4 2.018
IFNG interferon, gamma 2.0
IL13 interleukin 13 1.982
VIP vasoactive intestinal peptide 1.98
SPINK5 serine peptidase inhibitor, Kazal type 5 1.972
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.918
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.917
MMP1 matrix metallopeptidase 1 1.896
IL22 interleukin 22 1.892
DEFB1 defensin, beta 1 1.89
KLK14 kallikrein-related peptidase 14 1.885
IL10 interleukin 10 1.867
TSLP thymic stromal lymphopoietin 1.846
TLR4 toll-like receptor 4 1.824
BTNL2 butyrophilin-like 2 1.823
TGFB1 transforming growth factor, beta 1 1.763
IL31 interleukin 31 1.762
CMA1 chymase 1, mast cell 1.759
CCL2 chemokine (C-C motif) ligand 2 1.749
CXCL10 chemokine (C-X-C motif) ligand 10 1.743
IL18 interleukin 18 1.741
CD8A CD8a molecule 1.736
CCL20 chemokine (C-C motif) ligand 20 1.731
ANK1 ankyrin 1, erythrocytic 1.719
KLK6 kallikrein-related peptidase 6 1.695
S100A7A S100 calcium binding protein A7A 1.683
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.671
LTF lactotransferrin 1.668
DEFB104A defensin, beta 104A 1.667
NLRP3 NLR family, pyrin domain containing 3 1.656
MMP3 matrix metallopeptidase 3 1.653
IL5 interleukin 5 1.651
CDSN corneodesmosin 1.646
TACR3 tachykinin receptor 3 1.621
IL2 interleukin 2 1.614
CD1B CD1b molecule 1.61
CD1A CD1a molecule 1.608
DSG1 desmoglein 1 1.599
CD1E CD1e molecule 1.598
PECAM1 platelet/endothelial cell adhesion molecule 1 1.596
IL33 interleukin 33 1.592
CRP C-reactive protein, pentraxin-related 1.582
CD1C CD1c molecule 1.574
ADRA1A adrenoceptor alpha 1A 1.57
MMP8 matrix metallopeptidase 8 1.568
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.557
TPSAB1 tryptase alpha/beta 1 1.554
IVL involucrin 1.554
MYD88 myeloid differentiation primary response 88 1.547
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.542
ELN elastin 1.54
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.535
SPINK9 serine peptidase inhibitor, Kazal type 9 1.533
DEFB104B defensin, beta 104B 1.529
KNG1 kininogen 1 1.523
CXCL9 chemokine (C-X-C motif) ligand 9 1.51
MRGPRX1 MAS-related GPR, member X1 1.506
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.503
NGF nerve growth factor (beta polypeptide) 1.501
CD68 CD68 molecule 1.501
CD1D CD1d molecule 1.501
KLK13 kallikrein-related peptidase 13 1.5
FPR2 formyl peptide receptor 2 1.498
IFNA1 interferon, alpha 1 1.497
ICAM1 intercellular adhesion molecule 1 1.492
KRT10 keratin 10, type I 1.491
KRT1 keratin 1, type II 1.481
S100A8 S100 calcium binding protein A8 1.48
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.47
ACE angiotensin I converting enzyme 1.466
STAT1 signal transducer and activator of transcription 1, 91kDa 1.464
DEFB4B defensin, beta 4B 1.463
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.458
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.454
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.453
POMC proopiomelanocortin 1.45
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.448
ALB albumin 1.44
LACRT lacritin 1.438
AQP3 aquaporin 3 (Gill blood group) 1.434
FGF7 fibroblast growth factor 7 1.432
TLR3 toll-like receptor 3 1.431
HLA-DRA major histocompatibility complex, class II, DR alpha 1.423
CCL5 chemokine (C-C motif) ligand 5 1.417
LRRD1 leucine-rich repeats and death domain containing 1 1.412
MMP2 matrix metallopeptidase 2 1.412
DSC1 desmocollin 1 1.41
INS insulin 1.41
TLR9 toll-like receptor 9 1.405
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.404
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.397
IGF1 insulin-like growth factor 1 (somatomedin C) 1.388
JAK1 Janus kinase 1 1.386
IL37 interleukin 37 1.383
AHR aryl hydrocarbon receptor 1.381
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.378
EGF epidermal growth factor 1.377
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.364
PRSS3 protease, serine, 3 1.362
TLR7 toll-like receptor 7 1.36
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.356
KLK1 kallikrein 1 1.354
PDE4A phosphodiesterase 4A, cAMP-specific 1.349
IL3 interleukin 3 1.344
FGF16 fibroblast growth factor 16 1.34
CCL3 chemokine (C-C motif) ligand 3 1.338
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.338
FGF20 fibroblast growth factor 20 1.337
FGF4 fibroblast growth factor 4 1.335
FGF22 fibroblast growth factor 22 1.332
FGF5 fibroblast growth factor 5 1.332
IL17F interleukin 17F 1.332
MPO myeloperoxidase 1.331
FGF6 fibroblast growth factor 6 1.33
CLDN1 claudin 1 1.329
TYR tyrosinase 1.327
FGF17 fibroblast growth factor 17 1.326
CMC2 C-x(9)-C motif containing 2 1.325
FGF18 fibroblast growth factor 18 1.322
FGF3 fibroblast growth factor 3 1.317
HTN3 histatin 3 1.313
FGF9 fibroblast growth factor 9 1.313
KRT16 keratin 16, type I 1.313
ELANE elastase, neutrophil expressed 1.309
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 1.309
TLR8 toll-like receptor 8 1.308
FGF8 fibroblast growth factor 8 (androgen-induced) 1.307
FGF10 fibroblast growth factor 10 1.303
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.302
CALCA calcitonin-related polypeptide alpha 1.3
CXCL2 chemokine (C-X-C motif) ligand 2 1.298
LRRC43 leucine rich repeat containing 43 1.298
EGFR epidermal growth factor receptor 1.297
PON1 paraoxonase 1 1.295
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.288
SCP2 sterol carrier protein 2 1.283
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.281
SMNDC1 survival motor neuron domain containing 1 1.278
LCE1F late cornified envelope 1F 1.277
CTRL chymotrypsin-like 1.267
TIMP1 TIMP metallopeptidase inhibitor 1 1.265
PPARG peroxisome proliferator-activated receptor gamma 1.247
CRH corticotropin releasing hormone 1.241
DEFA1B defensin, alpha 1B 1.238
CCR6 chemokine (C-C motif) receptor 6 1.236
PI3 peptidase inhibitor 3, skin-derived 1.234
FGF2 fibroblast growth factor 2 (basic) 1.231
MYB v-myb avian myeloblastosis viral oncogene homolog 1.225
CCL27 chemokine (C-C motif) ligand 27 1.225
CCRL2 chemokine (C-C motif) receptor-like 2 1.219
CLDN7 claudin 7 1.216
FN1 fibronectin 1 1.215
CCL4 chemokine (C-C motif) ligand 4 1.214
TACR1 tachykinin receptor 1 1.214
IL4R interleukin 4 receptor 1.214
GSTM1 glutathione S-transferase mu 1 1.212
CASP14 caspase 14, apoptosis-related cysteine peptidase 1.208
FOXP3 forkhead box P3 1.206
JUN jun proto-oncogene 1.204
MORN3 MORN repeat containing 3 1.199
KITLG KIT ligand 1.196
NOD2 nucleotide-binding oligomerization domain containing 2 1.186
SLC26A8 solute carrier family 26 (anion exchanger), member 8 1.185
HBD hemoglobin, delta 1.185
PRTN3 proteinase 3 1.184
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.183
CD207 CD207 molecule, langerin 1.179
GBP5 guanylate binding protein 5 1.169
MPZL3 myelin protein zero-like 3 1.169
VIPR1 vasoactive intestinal peptide receptor 1 1.167
SPINK6 serine peptidase inhibitor, Kazal type 6 1.164
CD34 CD34 molecule 1.164
IFNA2 interferon, alpha 2 1.159
LRRCC1 leucine rich repeat and coiled-coil centrosomal protein 1 1.154
TRIM21 tripartite motif containing 21 1.153
TLR1 toll-like receptor 1 1.153
TGM1 transglutaminase 1 1.153
CCL17 chemokine (C-C motif) ligand 17 1.151
CTRB2 chymotrypsinogen B2 1.151
CD86 CD86 molecule 1.15
CTSS cathepsin S 1.149
CTRB1 chymotrypsinogen B1 1.145
KLK10 kallikrein-related peptidase 10 1.141
MRGPRD MAS-related GPR, member D 1.14
NPY neuropeptide Y 1.139
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.139
IL26 interleukin 26 1.135
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.124
S100A12 S100 calcium binding protein A12 1.121
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.12
CXCL11 chemokine (C-X-C motif) ligand 11 1.119
IFNB1 interferon, beta 1, fibroblast 1.118
SNX32 sorting nexin 32 1.118
SNAP25 synaptosomal-associated protein, 25kDa 1.117
VIPR2 vasoactive intestinal peptide receptor 2 1.117
CORT cortistatin 1.112
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.111
VEGFC vascular endothelial growth factor C 1.104
PXDN peroxidasin 1.096
ST14 suppression of tumorigenicity 14 (colon carcinoma) 1.096
LEP leptin 1.095
MAPK3 mitogen-activated protein kinase 3 1.095
ADRA2A adrenoceptor alpha 2A 1.091
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.091
OCA2 oculocutaneous albinism II 1.091
PXDNL peroxidasin-like 1.09
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 1.086
GAST gastrin 1.079
COL17A1 collagen, type XVII, alpha 1 1.079
IL36RN interleukin 36 receptor antagonist 1.078
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.078
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.077
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.071
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.068
TAC3 tachykinin 3 1.065
HRH1 histamine receptor H1 1.063
ACTB actin, beta 1.06
ACE2 angiotensin I converting enzyme 2 1.058
LRRC47 leucine rich repeat containing 47 1.054
CLDN23 claudin 23 1.053
HBEGF heparin-binding EGF-like growth factor 1.053
CPA3 carboxypeptidase A3 (mast cell) 1.051
LRRIQ3 leucine-rich repeats and IQ motif containing 3 1.05
MMP13 matrix metallopeptidase 13 1.049
HPGDS hematopoietic prostaglandin D synthase 1.045
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.044
GPX7 glutathione peroxidase 7 1.043
PTPRC protein tyrosine phosphatase, receptor type, C 1.042
JAK2 Janus kinase 2 1.041
TYK2 tyrosine kinase 2 1.04
MRGPRX3 MAS-related GPR, member X3 1.039
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 1.039
LRRC4 leucine rich repeat containing 4 1.036
EPRS1 glutamyl-prolyl-tRNA synthetase 1 1.035
SCN10A sodium channel, voltage gated, type X alpha subunit 1.034
MMP12 matrix metallopeptidase 12 1.034
GPX6 glutathione peroxidase 6 1.033
GPX5 glutathione peroxidase 5 1.032
CD80 CD80 molecule 1.032
GPX8 glutathione peroxidase 8 (putative) 1.031
CTSW cathepsin W 1.027
GPX3 glutathione peroxidase 3 1.025
CALML4 calmodulin-like 4 1.023
CALML6 calmodulin-like 6 1.023
TP53 tumor protein p53 1.023
CALML3 calmodulin-like 3 1.021
TRPV6 transient receptor potential cation channel, subfamily V, member 6 1.02
CALML5 calmodulin-like 5 1.02
RARG retinoic acid receptor, gamma 1.019
LCE1D late cornified envelope 1D 1.017
IL36G interleukin 36, gamma 1.01
RARS1 arginyl-tRNA synthetase 1 1.01
IL1R1 interleukin 1 receptor, type I 1.008
TGFB2 transforming growth factor, beta 2 1.007
IL1F10 interleukin 1 family, member 10 (theta) 1.006
IRF4 interferon regulatory factor 4 1.005
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.005
TLR5 toll-like receptor 5 1.005
GPX2 glutathione peroxidase 2 1.004
CXCR3 chemokine (C-X-C motif) receptor 3 1.003
TYRP1 tyrosinase-related protein 1 1.001