| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLIN2 | perilipin 2 | 0.226685 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.174485 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.102502 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0827289 |
| TF | transferrin | 0.0776303 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0754299 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0662593 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0661691 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0645533 |
| APOA2 | apolipoprotein A-II | 0.0581005 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0576965 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0575015 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0522772 |
| RPL3 | ribosomal protein L3 | 0.0515814 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0512987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0507326 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0476564 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0472757 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0459644 |
| RPS6 | ribosomal protein S6 | 0.0450188 |
| DSPP | dentin sialophosphoprotein | 0.0423856 |
| VEGFA | vascular endothelial growth factor A | 0.0412608 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0399364 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0383042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0381913 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.037819 |
| GOLGA4 | golgin A4 | 0.0365963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0348913 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0334057 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0331357 |
| RPS3 | ribosomal protein S3 | 0.0331038 |
| SQSTM1 | sequestosome 1 | 0.033094 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0330767 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330296 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0328299 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0326948 |
| KIF5B | kinesin family member 5B | 0.0318386 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0316448 |
| ENO1 | enolase 1, (alpha) | 0.0313854 |
| ANXA5 | annexin A5 | 0.0311155 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0311095 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0306443 |
| TXNRD1 | thioredoxin reductase 1 | 0.0303405 |
| DIAPH1 | diaphanous-related formin 1 | 0.0288356 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284679 |
| INSIG2 | insulin induced gene 2 | 0.0279621 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0277536 |
| SET | SET nuclear proto-oncogene | 0.0266022 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0262871 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0262318 |
| CCNL1 | cyclin L1 | 0.0261296 |
| RPL11 | ribosomal protein L11 | 0.0257224 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0255027 |
| ITGAV | integrin, alpha V | 0.0255014 |
| JAG1 | jagged 1 | 0.0253529 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0245502 |
| LDHA | lactate dehydrogenase A | 0.0242391 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.024115 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0240189 |
| FABP1 | fatty acid binding protein 1, liver | 0.0239435 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0239018 |
| AFDN | afadin, adherens junction formation factor | 0.0238472 |
| GOLGB1 | golgin B1 | 0.0235937 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0229457 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0227435 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0225879 |
| NGLY1 | N-glycanase 1 | 0.0225343 |
| FMNL2 | formin-like 2 | 0.0224501 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0223895 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.022369 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0221749 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0220791 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0220715 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.021878 |
| FNBP1L | formin binding protein 1-like | 0.0217209 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0217045 |
| CCNY | cyclin Y | 0.0216782 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0215755 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0215748 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0213785 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0213479 |
| IPO5 | importin 5 | 0.0213347 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0212792 |
| TLE4 | transducin-like enhancer of split 4 | 0.0212384 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0209451 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.02092 |
| IPO7 | importin 7 | 0.020912 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0208039 |
| RLF | rearranged L-myc fusion | 0.0207635 |
| TCP1 | t-complex 1 | 0.0204833 |
| RPL7 | ribosomal protein L7 | 0.0204577 |
| CLTC | clathrin, heavy chain (Hc) | 0.0204533 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0202727 |
| ITGA6 | integrin, alpha 6 | 0.0201599 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0201227 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0197422 |
| RPL26 | ribosomal protein L26 | 0.0195098 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0194703 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0192276 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0191756 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.25202 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.237376 |
| FN1 | fibronectin 1 | -0.118842 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.117535 |
| MT2A | metallothionein 2A | -0.106796 |
| C3 | complement component 3 | -0.106088 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.105769 |
| GPC3 | glypican 3 | -0.103058 |
| IGF2 | insulin-like growth factor 2 | -0.0938029 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0935808 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0886778 |
| EHBP1 | EH domain binding protein 1 | -0.0884751 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0884749 |
| FRMD5 | FERM domain containing 5 | -0.0731323 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.069594 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0670237 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0669079 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0659344 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0652204 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0648597 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0633195 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0612269 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0605871 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0603871 |
| ACTN4 | actinin, alpha 4 | -0.0599604 |
| SVIL | supervillin | -0.0589311 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0578729 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0574568 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0555342 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0538854 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0533251 |
| RRBP1 | ribosome binding protein 1 | -0.0485292 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0475483 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0466365 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0464122 |
| TMSB10 | thymosin beta 10 | -0.0462213 |
| ZFHX3 | zinc finger homeobox 3 | -0.0457568 |
| KIAA1217 | KIAA1217 | -0.0444546 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0443664 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0443408 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0438811 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0419804 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0419745 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0418756 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0411466 |
| PTCHD4 | patched domain containing 4 | -0.0393947 |
| A2M | alpha-2-macroglobulin | -0.038437 |
| VCL | vinculin | -0.0383042 |
| EGR1 | early growth response 1 | -0.0382537 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0382277 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0381741 |
| FAM135A | family with sequence similarity 135, member A | -0.0377695 |
| MRTFA | myocardin related transcription factor A | -0.0372911 |
| PEG10 | paternally expressed 10 | -0.0364585 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0364403 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0362859 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0360169 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0359365 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0351684 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0348134 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0347517 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0340744 |
| FOXP1 | forkhead box P1 | -0.0338568 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0327849 |
| SDC4 | syndecan 4 | -0.0324766 |
| RPL35A | ribosomal protein L35a | -0.0312994 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0312795 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0312394 |
| MALT1 | MALT1 paracaspase | -0.0309474 |
| ITGA1 | integrin, alpha 1 | -0.0304396 |
| TMEM123 | transmembrane protein 123 | -0.0303712 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0300521 |
| ITGB5 | integrin, beta 5 | -0.0298868 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.029785 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0297213 |
| BCL2L1 | BCL2-like 1 | -0.029622 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0295251 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0294495 |
| RNF213 | ring finger protein 213 | -0.0293468 |
| H1-0 | H1.0 linker histone | -0.0292511 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0291795 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.029121 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0291162 |
| TBCK | TBC1 domain containing kinase | -0.0290989 |
| RPL37A | ribosomal protein L37a | -0.0289137 |
| BPTF | bromodomain PHD finger transcription factor | -0.0289118 |
| CTSB | cathepsin B | -0.0288736 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0285023 |
| RPLP2 | ribosomal protein, large, P2 | -0.0284215 |
| ATXN1 | ataxin 1 | -0.0278697 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0278572 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0278529 |
| CNKSR3 | CNKSR family member 3 | -0.0276567 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0276393 |
| PKP4 | plakophilin 4 | -0.0274096 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0273579 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | -0.027287 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0272442 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0271823 |
| CFB | complement factor B | -0.027176 |
