| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rosiglitazone_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.216077 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.121277 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0984312 |
| EREG | epiregulin | 0.0952342 |
| TXNIP | thioredoxin interacting protein | 0.0824812 |
| FAM13A | family with sequence similarity 13, member A | 0.0805089 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0764333 |
| RNF145 | ring finger protein 145 | 0.0741106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0701117 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0669973 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0664703 |
| GOLGA4 | golgin A4 | 0.0649112 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0596825 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0562972 |
| RBM39 | RNA binding motif protein 39 | 0.0553477 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0550949 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.048636 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0485575 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0484916 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0474358 |
| NUP58 | nucleoporin 58 | 0.0466658 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0452635 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0447467 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0437538 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0426519 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0426393 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0411926 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0406536 |
| TFG | TRK-fused gene | 0.0400355 |
| ZNF292 | zinc finger protein 292 | 0.0397726 |
| WDR45B | WD repeat domain 45B | 0.038538 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0378074 |
| CAB39 | calcium binding protein 39 | 0.0365218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355527 |
| FNBP1L | formin binding protein 1-like | 0.0354407 |
| MATR3 | matrin 3 | 0.0350293 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0348945 |
| YME1L1 | YME1-like 1 ATPase | 0.0345312 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0343525 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0342907 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0338522 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0336525 |
| USP3 | ubiquitin specific peptidase 3 | 0.0331934 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0331496 |
| COPA | coatomer protein complex, subunit alpha | 0.0329469 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0326238 |
| ANXA1 | annexin A1 | 0.0325926 |
| DSPP | dentin sialophosphoprotein | 0.0320504 |
| OGA | O-GlcNAcase | 0.0318997 |
| MED13L | mediator complex subunit 13-like | 0.0313579 |
| COG5 | component of oligomeric golgi complex 5 | 0.0311683 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0309924 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.030919 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0308319 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0307689 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0305243 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0304953 |
| ITGA6 | integrin, alpha 6 | 0.0304784 |
| TES | testin LIM domain protein | 0.0304366 |
| NCKAP1 | NCK-associated protein 1 | 0.0300692 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0300484 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.029927 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0298624 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0291969 |
| NEK7 | NIMA-related kinase 7 | 0.0291214 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0290425 |
| RLF | rearranged L-myc fusion | 0.0289327 |
| SPAG9 | sperm associated antigen 9 | 0.0289068 |
| TXNRD1 | thioredoxin reductase 1 | 0.0289021 |
| RREB1 | ras responsive element binding protein 1 | 0.0288925 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0287812 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0283341 |
| YBX1 | Y box binding protein 1 | 0.0282083 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0280283 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0275456 |
| OXSR1 | oxidative stress responsive 1 | 0.0274909 |
| KIF5B | kinesin family member 5B | 0.0269869 |
| RPL3 | ribosomal protein L3 | 0.026915 |
| CCNL1 | cyclin L1 | 0.0268352 |
| HELZ | helicase with zinc finger | 0.0266298 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0265706 |
| LDHA | lactate dehydrogenase A | 0.0265216 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0262612 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0260445 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0259046 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0258393 |
| PRRC2C | proline-rich coiled-coil 2C | 0.025561 |
| GDF15 | growth differentiation factor 15 | 0.0254423 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0253224 |
| VEGFA | vascular endothelial growth factor A | 0.0252441 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0252346 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0252289 |
| S100P | S100 calcium binding protein P | 0.0250531 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0250531 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0248173 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0247048 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0246974 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.024661 |
| DENND4C | DENN/MADD domain containing 4C | 0.0246167 |
| YTHDC1 | YTH domain containing 1 | 0.0245674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.212386 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.133212 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.121247 |
| FAT1 | FAT atypical cadherin 1 | -0.0987789 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0951602 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0950953 |
| VCL | vinculin | -0.0928643 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0919607 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0911962 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0903726 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0876899 |
| TMSB10 | thymosin beta 10 | -0.0842479 |
| ONECUT3 | one cut homeobox 3 | -0.0840948 |
| MYO1E | myosin IE | -0.0794412 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0761046 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.072022 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.071632 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0691813 |
| CADPS | Ca++-dependent secretion activator | -0.066503 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0664116 |
| SMYD3 | SET and MYND domain containing 3 | -0.0651086 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0615652 |
| RNF217 | ring finger protein 217 | -0.057543 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0563042 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0555541 |
| FHIT | fragile histidine triad | -0.054124 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0526833 |
| ACTG1 | actin gamma 1 | -0.0526281 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.051354 |
| FRMD5 | FERM domain containing 5 | -0.0498563 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0486336 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0484447 |
| RAD51B | RAD51 paralog B | -0.0455983 |
| AHNAK | AHNAK nucleoprotein | -0.0439426 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0431647 |
| EGFR | epidermal growth factor receptor | -0.04253 |
| LAMA4 | laminin, alpha 4 | -0.0422132 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.041906 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0415769 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0406672 |
| EXOC4 | exocyst complex component 4 | -0.040316 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0400654 |
| NRXN3 | neurexin 3 | -0.0398156 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0391301 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0385507 |
| ACTN4 | actinin, alpha 4 | -0.0380472 |
| FOXP1 | forkhead box P1 | -0.0369412 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0368303 |
| ATXN1 | ataxin 1 | -0.0366745 |
| ASPH | aspartate beta-hydroxylase | -0.0359402 |
| PTMA | prothymosin, alpha | -0.0353573 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0352055 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0351912 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0348322 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0348041 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0338224 |
| DENND1A | DENN/MADD domain containing 1A | -0.0336863 |
| GPHN | gephyrin | -0.033374 |
| PALLD | palladin, cytoskeletal associated protein | -0.0328458 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0326689 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.03259 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0323073 |
| SH3D19 | SH3 domain containing 19 | -0.0322442 |
| NEBL | nebulette | -0.032043 |
| TNS4 | tensin 4 | -0.0318086 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.031655 |
| RPL35A | ribosomal protein L35a | -0.0316154 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0314834 |
| RIN2 | Ras and Rab interactor 2 | -0.0314799 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.031455 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0313128 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0311561 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0310674 |
| MECOM | MDS1 and EVI1 complex locus | -0.0309728 |
| POF1B | premature ovarian failure, 1B | -0.0308074 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0305624 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0300414 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0300161 |
| PCDH9 | protocadherin 9 | -0.0299423 |
| NFIA | nuclear factor I/A | -0.0297812 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0297731 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0297079 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0296377 |
| MYO1D | myosin ID | -0.0293145 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.028904 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.028688 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0280293 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0279534 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0279195 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0278259 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0277751 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0277665 |
| TPM4 | tropomyosin 4 | -0.0276939 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0275399 |
| FLNB | filamin B, beta | -0.0273394 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0271502 |
| NBEAL1 | neurobeachin-like 1 | -0.0266909 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0265611 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.026446 |
| PKP2 | plakophilin 2 | -0.0263592 |
