| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.215814 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.189932 |
| TMSB4X | thymosin beta 4, X-linked | 0.123355 |
| POTEF | POTE ankyrin domain family, member F | 0.111242 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.104943 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0844593 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0843162 |
| MATR3 | matrin 3 | 0.0820695 |
| RPS6 | ribosomal protein S6 | 0.0777674 |
| SET | SET nuclear proto-oncogene | 0.0709103 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0705863 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0692771 |
| ENO1 | enolase 1, (alpha) | 0.0626345 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0619288 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0584325 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0584115 |
| CENPF | centromere protein F, 350/400kDa | 0.0582422 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0554891 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.053557 |
| ZNF292 | zinc finger protein 292 | 0.0529442 |
| RPL26 | ribosomal protein L26 | 0.0527434 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0487465 |
| RPL11 | ribosomal protein L11 | 0.0474138 |
| SLK | STE20-like kinase | 0.046488 |
| DST | dystonin | 0.044947 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0448947 |
| PLIN2 | perilipin 2 | 0.0432375 |
| RPS12 | ribosomal protein S12 | 0.0431923 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0431812 |
| XPO1 | exportin 1 | 0.0430626 |
| EZR | ezrin | 0.0422486 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0422285 |
| MSN | moesin | 0.0421969 |
| OGA | O-GlcNAcase | 0.041324 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0412503 |
| TPM3 | tropomyosin 3 | 0.0409623 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0408777 |
| NUP58 | nucleoporin 58 | 0.0394756 |
| YBX1 | Y box binding protein 1 | 0.0394527 |
| GOLGA4 | golgin A4 | 0.0393627 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0393233 |
| RPL37A | ribosomal protein L37a | 0.0392976 |
| PCBP2 | poly(rC) binding protein 2 | 0.0392251 |
| RPS19 | ribosomal protein S19 | 0.0391804 |
| CCNL1 | cyclin L1 | 0.0369474 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0362572 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0359629 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0355724 |
| PTMA | prothymosin, alpha | 0.0353588 |
| B2M | beta-2-microglobulin | 0.0353269 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0350248 |
| RPL36 | ribosomal protein L36 | 0.0347521 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0347487 |
| RPL23 | ribosomal protein L23 | 0.034736 |
| TXNIP | thioredoxin interacting protein | 0.0346747 |
| RPL3 | ribosomal protein L3 | 0.0343395 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0342521 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0339058 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0337092 |
| RNF145 | ring finger protein 145 | 0.0336385 |
| RPS8 | ribosomal protein S8 | 0.0335635 |
| RBM25 | RNA binding motif protein 25 | 0.0328652 |
| TPR | translocated promoter region, nuclear basket protein | 0.0328091 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0327101 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0320948 |
| WDR43 | WD repeat domain 43 | 0.0318857 |
| RACK1 | receptor for activated C kinase 1 | 0.03137 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0312906 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0312713 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312536 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.030941 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0307213 |
| SETD5 | SET domain containing 5 | 0.0307173 |
| PLK2 | polo-like kinase 2 | 0.0304786 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0304211 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0302791 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0302681 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0300947 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0297532 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0297239 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0296129 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0292631 |
| HELZ | helicase with zinc finger | 0.0291912 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0291436 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0290381 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0289392 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0287129 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.028588 |
| SNX3 | sorting nexin 3 | 0.0285858 |
| QKI | QKI, KH domain containing, RNA binding | 0.028491 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0278779 |
| DSTN | destrin (actin depolymerizing factor) | 0.0277939 |
| HDGF | hepatoma-derived growth factor | 0.02776 |
| CDC73 | cell division cycle 73 | 0.0275872 |
| RPLP2 | ribosomal protein, large, P2 | 0.0275527 |
| HMGB2 | high mobility group box 2 | 0.0274259 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0274143 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0271388 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0270993 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0269646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.268494 |
| TXNRD1 | thioredoxin reductase 1 | -0.168143 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.147415 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.11658 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0989528 |
| TMSB10 | thymosin beta 10 | -0.0958417 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0846558 |
| CD44 | CD44 molecule (Indian blood group) | -0.0838819 |
| AHNAK | AHNAK nucleoprotein | -0.0837165 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0806133 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0799521 |
| MT2A | metallothionein 2A | -0.0790826 |
| VIM | vimentin | -0.0757234 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0706691 |
| EGR1 | early growth response 1 | -0.0693024 |
| ACTG1 | actin gamma 1 | -0.067776 |
| EMP1 | epithelial membrane protein 1 | -0.0622331 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0599106 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0586393 |
| TP63 | tumor protein p63 | -0.0583478 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0551306 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0550544 |
| CMIP | c-Maf inducing protein | -0.0545975 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0533655 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0529118 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0527539 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0493472 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.048886 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0461072 |
| MT1X | metallothionein 1X | -0.0458184 |
| JUN | jun proto-oncogene | -0.045806 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0414762 |
| RGS4 | regulator of G-protein signaling 4 | -0.0401682 |
| RIGI | RNA sensor RIG-I | -0.0398536 |
| RUNX1 | runt-related transcription factor 1 | -0.0384041 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0367011 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0366891 |
| CANX | calnexin | -0.0361562 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0360509 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0354954 |
| USP34 | ubiquitin specific peptidase 34 | -0.0345498 |
| HPCAL1 | hippocalcin-like 1 | -0.0344874 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.034045 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0338361 |
| UBC | ubiquitin C | -0.0333448 |
| TMEM41B | transmembrane protein 41B | -0.0325723 |
| FBXO11 | F-box protein 11 | -0.0322247 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0318948 |
| OSMR | oncostatin M receptor | -0.0312955 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0310605 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0304987 |
| JMJD1C | jumonji domain containing 1C | -0.0302984 |
| RAI1 | retinoic acid induced 1 | -0.0301708 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0300704 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0293889 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0276695 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0275157 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0269755 |
| ERBIN | erbb2 interacting protein | -0.0268056 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0267579 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263863 |
| VMP1 | vacuole membrane protein 1 | -0.0262876 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0260916 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260817 |
| HDAC9 | histone deacetylase 9 | -0.0257532 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.025695 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0256016 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0254631 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0254628 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0252812 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0251888 |
| AFF4 | AF4/FMR2 family, member 4 | -0.025003 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0246982 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0246243 |
| CDK12 | cyclin-dependent kinase 12 | -0.0244294 |
| YBX3 | Y box binding protein 3 | -0.0243251 |
| HDLBP | high density lipoprotein binding protein | -0.0242817 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0242256 |
| ARMC9 | armadillo repeat containing 9 | -0.023939 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0239256 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0238341 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0236799 |
| PLSCR1 | phospholipid scramblase 1 | -0.0235933 |
| BMERB1 | bMERB domain containing 1 | -0.0234759 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0234449 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0233992 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0227759 |
| INTS6 | integrator complex subunit 6 | -0.0227338 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0226066 |
| RPS27A | ribosomal protein S27a | -0.0225615 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0222786 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0220315 |
| UPP1 | uridine phosphorylase 1 | -0.0220074 |
| PATJ | PATJ crumbs cell polarity complex component | -0.021736 |
| CUL1 | cullin 1 | -0.0216385 |
| SGMS2 | sphingomyelin synthase 2 | -0.0215832 |
| TAOK1 | TAO kinase 1 | -0.0213715 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0213535 |
| NBEAL1 | neurobeachin-like 1 | -0.0212166 |
| AHI1 | Abelson helper integration site 1 | -0.0211058 |
