| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0751876 |
| FAM13A | family with sequence similarity 13, member A | 0.0687271 |
| RNF145 | ring finger protein 145 | 0.0620329 |
| TOP1 | topoisomerase (DNA) I | 0.0515828 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0492208 |
| ATP13A3 | ATPase type 13A3 | 0.0469347 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0465204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0406116 |
| TPD52 | tumor protein D52 | 0.0388159 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0388053 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385901 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0368862 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.036677 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.036407 |
| NCKAP1 | NCK-associated protein 1 | 0.0352916 |
| ANXA5 | annexin A5 | 0.0346943 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0345741 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0342898 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0338252 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0302485 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0289521 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0281732 |
| HELZ | helicase with zinc finger | 0.0267518 |
| ENO1 | enolase 1, (alpha) | 0.0263463 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0253787 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0249196 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0248629 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0247419 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0247303 |
| LMO7 | LIM domain 7 | 0.0246717 |
| USP3 | ubiquitin specific peptidase 3 | 0.0245293 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0243168 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0241399 |
| DSPP | dentin sialophosphoprotein | 0.0239106 |
| MSN | moesin | 0.023683 |
| RAD21 | RAD21 homolog (S. pombe) | 0.022844 |
| ITSN2 | intersectin 2 | 0.022826 |
| UVRAG | UV radiation resistance associated | 0.022788 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0218464 |
| NGLY1 | N-glycanase 1 | 0.0215467 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0214258 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0212834 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0210934 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0209545 |
| MATR3 | matrin 3 | 0.020862 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0208251 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0199846 |
| ZNF292 | zinc finger protein 292 | 0.0198264 |
| RLF | rearranged L-myc fusion | 0.0197725 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0197002 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0194821 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0194164 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0193652 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0192291 |
| YBX1 | Y box binding protein 1 | 0.018995 |
| NUP58 | nucleoporin 58 | 0.0188773 |
| NPAS2 | neuronal PAS domain protein 2 | 0.018611 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0182943 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0182275 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0181362 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.018002 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0179353 |
| ZFR | zinc finger RNA binding protein | 0.0178766 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0178595 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0177998 |
| QKI | QKI, KH domain containing, RNA binding | 0.0177789 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0177255 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0171431 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0170811 |
| MYOF | myoferlin | 0.0170693 |
| CD109 | CD109 molecule | 0.0169939 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0168994 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0166505 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0165906 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0165571 |
| CCNY | cyclin Y | 0.0163922 |
| TFG | TRK-fused gene | 0.0160823 |
| ECT2 | epithelial cell transforming 2 | 0.0159253 |
| FNBP1L | formin binding protein 1-like | 0.0158252 |
| TMEM45B | transmembrane protein 45B | 0.0155663 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0155002 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0152645 |
| FLNB | filamin B, beta | 0.0152078 |
| STC1 | stanniocalcin 1 | 0.0148653 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.014663 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0145459 |
| AMOTL1 | angiomotin like 1 | 0.0144026 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0143898 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.014243 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0140267 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0139591 |
| SLMAP | sarcolemma associated protein | 0.0138503 |
| WDR45B | WD repeat domain 45B | 0.0137868 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0136941 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0136598 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.013615 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0136133 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.013486 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0134367 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0133583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349116 |
| EGFR | epidermal growth factor receptor | -0.19151 |
| NDRG1 | N-myc downstream regulated 1 | -0.122125 |
| EGR1 | early growth response 1 | -0.0892039 |
| TMSB10 | thymosin beta 10 | -0.076983 |
| MCL1 | myeloid cell leukemia 1 | -0.0701782 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0694539 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0669958 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0584343 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0554793 |
| INTS6 | integrator complex subunit 6 | -0.0551667 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0529517 |
| TXNRD1 | thioredoxin reductase 1 | -0.0528608 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0481936 |
| JMJD1C | jumonji domain containing 1C | -0.0480256 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0457866 |
| PKM | pyruvate kinase, muscle | -0.0454109 |
| PATJ | PATJ crumbs cell polarity complex component | -0.044842 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0447463 |
| GOLGB1 | golgin B1 | -0.0440262 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0424815 |
| MT2A | metallothionein 2A | -0.04244 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0422049 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0418517 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0407175 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0402787 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0402379 |
| MYO1E | myosin IE | -0.0401658 |
| RPL35A | ribosomal protein L35a | -0.0399197 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0394975 |
| NABP1 | nucleic acid binding protein 1 | -0.039092 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0383083 |
| EFNA5 | ephrin-A5 | -0.0378387 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0370606 |
| ANKRD12 | ankyrin repeat domain 12 | -0.036839 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0367374 |
| RAD51B | RAD51 paralog B | -0.0366058 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0358128 |
| SLTM | SAFB-like, transcription modulator | -0.0339229 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0335985 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0335863 |
| ACTG1 | actin gamma 1 | -0.0332088 |
| CST3 | cystatin C | -0.0331257 |
| SEC61G | Sec61 gamma subunit | -0.0327138 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0327 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0320463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0318115 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0309377 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0306271 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0302755 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0299587 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299484 |
| RPL37A | ribosomal protein L37a | -0.028513 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.028314 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0281789 |
| USP34 | ubiquitin specific peptidase 34 | -0.0278961 |
| KIAA1217 | KIAA1217 | -0.0277145 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0277048 |
| HLA-B | major histocompatibility complex, class I, B | -0.0275852 |
| VMP1 | vacuole membrane protein 1 | -0.0273474 |
| S100A10 | S100 calcium binding protein A10 | -0.0268707 |
| RNF213 | ring finger protein 213 | -0.026781 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0265393 |
| RPL31 | ribosomal protein L31 | -0.0263834 |
| HM13 | histocompatibility (minor) 13 | -0.026334 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0258511 |
| RPS12 | ribosomal protein S12 | -0.0256885 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0256254 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0255044 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0252048 |
| SYAP1 | synapse associated protein 1 | -0.0251506 |
| B2M | beta-2-microglobulin | -0.0249882 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0247573 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0247314 |
| GPHN | gephyrin | -0.0247096 |
| RPS29 | ribosomal protein S29 | -0.0246742 |
| RPS3 | ribosomal protein S3 | -0.02464 |
| RPS8 | ribosomal protein S8 | -0.0246025 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.024573 |
| PRKCA | protein kinase C, alpha | -0.0242607 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0241461 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0240668 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0239949 |
| OSMR | oncostatin M receptor | -0.0239312 |
| RPS25 | ribosomal protein S25 | -0.0236486 |
| FNIP1 | folliculin interacting protein 1 | -0.0236336 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0235834 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0233713 |
| VCL | vinculin | -0.0230687 |
| RPLP1 | ribosomal protein, large, P1 | -0.0228808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0227132 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0226765 |
| RPS2 | ribosomal protein S2 | -0.0225165 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0225164 |
| SP100 | SP100 nuclear antigen | -0.022295 |
| CES1 | carboxylesterase 1 | -0.0222274 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0221451 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0220974 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0217513 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0211848 |
