| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.278358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103834 |
| GRAMD1B | GRAM domain containing 1B | 0.0800031 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0695293 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0686931 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0660476 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0619251 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0570047 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0553688 |
| FGB | fibrinogen beta chain | 0.0503727 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0499923 |
| RTN4 | reticulon 4 | 0.0472747 |
| NRG1 | neuregulin 1 | 0.0432492 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0411798 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0386917 |
| KIF5B | kinesin family member 5B | 0.0385688 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0362888 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0361881 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.036054 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0359249 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0337314 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0336853 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0331535 |
| ENO1 | enolase 1, (alpha) | 0.0323446 |
| ANXA5 | annexin A5 | 0.0308726 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0284931 |
| USP3 | ubiquitin specific peptidase 3 | 0.0284925 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0279342 |
| HDAC9 | histone deacetylase 9 | 0.0275112 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.027345 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0271739 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0270496 |
| MATR3 | matrin 3 | 0.026906 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0268145 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0264676 |
| FGG | fibrinogen gamma chain | 0.0256381 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0256164 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.025398 |
| PFDN2 | prefoldin subunit 2 | 0.0252966 |
| OSMR | oncostatin M receptor | 0.0249875 |
| WDR43 | WD repeat domain 43 | 0.0248002 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0235797 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0233129 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.0231868 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0228636 |
| MKI67 | marker of proliferation Ki-67 | 0.0226404 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0225881 |
| RPL4 | ribosomal protein L4 | 0.0224967 |
| LAMB1 | laminin, beta 1 | 0.0222826 |
| IMMT | inner membrane protein, mitochondrial | 0.0218183 |
| TNPO1 | transportin 1 | 0.0217928 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0216789 |
| AREG | amphiregulin | 0.0215169 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0213217 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0208465 |
| TMEM123 | transmembrane protein 123 | 0.0208403 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0207417 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0205058 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0203379 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.02028 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0202105 |
| CCNL1 | cyclin L1 | 0.0201926 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0201754 |
| TPM3 | tropomyosin 3 | 0.0199668 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0193092 |
| RPLP0 | ribosomal protein, large, P0 | 0.0191929 |
| MSN | moesin | 0.0190324 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0189178 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.0188315 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0186015 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0184276 |
| XPO1 | exportin 1 | 0.0183192 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0181485 |
| TPM4 | tropomyosin 4 | 0.0180275 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0180042 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0179851 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0177273 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0176298 |
| TPR | translocated promoter region, nuclear basket protein | 0.0174973 |
| SYAP1 | synapse associated protein 1 | 0.0173666 |
| YBX3 | Y box binding protein 3 | 0.0172892 |
| AHR | aryl hydrocarbon receptor | 0.0172587 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0171578 |
| RSPO3 | R-spondin 3 | 0.0171151 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0169419 |
| NUP58 | nucleoporin 58 | 0.0169308 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.016914 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0168876 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0167744 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0167726 |
| NUP153 | nucleoporin 153kDa | 0.0167514 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0166075 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0163776 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0161636 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.016094 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0160391 |
| YME1L1 | YME1-like 1 ATPase | 0.0158217 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0157644 |
| VMP1 | vacuole membrane protein 1 | 0.0157572 |
| MAP1B | microtubule-associated protein 1B | 0.0156342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.180741 |
| MT2A | metallothionein 2A | -0.118646 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.115549 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.115425 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0955548 |
| CMIP | c-Maf inducing protein | -0.0927126 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0898074 |
| FMNL2 | formin-like 2 | -0.088472 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0834276 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0803095 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0758971 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0705708 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0697754 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.062995 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0617265 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0590389 |
| FTL | ferritin, light polypeptide | -0.0551773 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0527429 |
| FLNB | filamin B, beta | -0.0517977 |
| ACTG1 | actin gamma 1 | -0.0506603 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0486945 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.048616 |
| VIM | vimentin | -0.0469025 |
| EGFR | epidermal growth factor receptor | -0.0467081 |
| RAD51B | RAD51 paralog B | -0.0462421 |
| RPL37A | ribosomal protein L37a | -0.0459945 |
| NEGR1 | neuronal growth regulator 1 | -0.0453891 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0432277 |
| NEBL | nebulette | -0.0429784 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0427132 |
| PYGL | phosphorylase, glycogen, liver | -0.0417788 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0408405 |
| NDRG1 | N-myc downstream regulated 1 | -0.0401364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0393873 |
| ATXN1 | ataxin 1 | -0.0391624 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0386689 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384738 |
| PARD3 | par-3 family cell polarity regulator | -0.0372641 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0370685 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0368419 |
| CTBP2 | C-terminal binding protein 2 | -0.0365015 |
| MYO1E | myosin IE | -0.0362384 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0359483 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0356565 |
| USP34 | ubiquitin specific peptidase 34 | -0.0353884 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.035304 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0349544 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0339983 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0336971 |
| FAM107B | family with sequence similarity 107, member B | -0.0331294 |
| UTRN | utrophin | -0.032643 |
| CUX1 | cut-like homeobox 1 | -0.0324267 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0322343 |
| RPL36 | ribosomal protein L36 | -0.031904 |
| DST | dystonin | -0.0318503 |
| IGF2 | insulin-like growth factor 2 | -0.0316196 |
| RPL23 | ribosomal protein L23 | -0.0312163 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0311736 |
| ACTN1 | actinin, alpha 1 | -0.0309357 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0303805 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0302776 |
| RPS12 | ribosomal protein S12 | -0.0300648 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0300577 |
| EFNA5 | ephrin-A5 | -0.0299957 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0297096 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0293395 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.02933 |
| RPS3 | ribosomal protein S3 | -0.0289703 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0286033 |
| CAVIN1 | caveolae associated protein 1 | -0.0284896 |
| HLA-B | major histocompatibility complex, class I, B | -0.0282289 |
| RPL31 | ribosomal protein L31 | -0.0281777 |
| NHSL1 | NHS-like 1 | -0.0279931 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0279528 |
| INTS6 | integrator complex subunit 6 | -0.0276654 |
| AHNAK | AHNAK nucleoprotein | -0.0272074 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0267743 |
| VCL | vinculin | -0.0266316 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0265583 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0263488 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0263483 |
| RPS19 | ribosomal protein S19 | -0.026195 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0260367 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0258754 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0255639 |
| GNAS | GNAS complex locus | -0.0248772 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0246893 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0245041 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0244686 |
| PRKCA | protein kinase C, alpha | -0.0240599 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0240128 |
| RPS17 | ribosomal protein S17 | -0.0240011 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0239321 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0236817 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0236038 |
| SNX14 | sorting nexin 14 | -0.0235867 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0232008 |
| SVIL | supervillin | -0.0230849 |
| NLK | nemo-like kinase | -0.0228008 |
| EHBP1 | EH domain binding protein 1 | -0.022561 |
