| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.151367 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.135922 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.124071 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.120914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109846 |
| GOLGA4 | golgin A4 | 0.108404 |
| RPS6 | ribosomal protein S6 | 0.0918653 |
| NDRG1 | N-myc downstream regulated 1 | 0.091085 |
| IGF2 | insulin-like growth factor 2 | 0.0887533 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0877445 |
| RSF1 | remodeling and spacing factor 1 | 0.0865358 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0722208 |
| FLNB | filamin B, beta | 0.0707436 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.064684 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0628811 |
| PTMA | prothymosin, alpha | 0.0604928 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0551691 |
| ENO1 | enolase 1, (alpha) | 0.0550479 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.054332 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0540566 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.051799 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0516764 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0509708 |
| RPL37A | ribosomal protein L37a | 0.049714 |
| ATP13A3 | ATPase type 13A3 | 0.049149 |
| RPS19 | ribosomal protein S19 | 0.0485286 |
| MTDH | metadherin | 0.0484223 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.048357 |
| RPL11 | ribosomal protein L11 | 0.0475067 |
| BRD2 | bromodomain containing 2 | 0.0469202 |
| SON | SON DNA binding protein | 0.0468593 |
| GNAS | GNAS complex locus | 0.0466444 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0465662 |
| FAM13A | family with sequence similarity 13, member A | 0.0464266 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.045289 |
| BBX | bobby sox homolog (Drosophila) | 0.0447308 |
| OGA | O-GlcNAcase | 0.0439376 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0439011 |
| ADAR | adenosine deaminase, RNA-specific | 0.0438716 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0438608 |
| TOP1 | topoisomerase (DNA) I | 0.0437589 |
| CCNL1 | cyclin L1 | 0.0436568 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0431516 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0427915 |
| PCBP2 | poly(rC) binding protein 2 | 0.0422247 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.042148 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0415084 |
| OPTN | optineurin | 0.0411801 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0407328 |
| WDR45B | WD repeat domain 45B | 0.0406731 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0401529 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0398967 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0392882 |
| RPS12 | ribosomal protein S12 | 0.0389142 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0384809 |
| CALR | calreticulin | 0.038261 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0381995 |
| NOP58 | NOP58 ribonucleoprotein | 0.037691 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0375224 |
| CANX | calnexin | 0.0372291 |
| RPS25 | ribosomal protein S25 | 0.0372152 |
| PGK1 | phosphoglycerate kinase 1 | 0.0371643 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0369808 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0368285 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0366557 |
| PHF21A | PHD finger protein 21A | 0.0364806 |
| NUP58 | nucleoporin 58 | 0.0364645 |
| RPL7A | ribosomal protein L7a | 0.0363858 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0363527 |
| FTL | ferritin, light polypeptide | 0.0362564 |
| SET | SET nuclear proto-oncogene | 0.0362232 |
| ITSN2 | intersectin 2 | 0.0358923 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0356458 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0356286 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0354425 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0353812 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0353337 |
| ANXA1 | annexin A1 | 0.0352301 |
| STC1 | stanniocalcin 1 | 0.0350751 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0348557 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0347818 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | 0.0346855 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0346731 |
| RPS16 | ribosomal protein S16 | 0.0344839 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.034464 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0340509 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0337964 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0335096 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0330012 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0329517 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0327304 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0327048 |
| MYOF | myoferlin | 0.0326905 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0325734 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0321554 |
| SEPTIN2 | septin 2 | 0.0307506 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0305469 |
| HLA-B | major histocompatibility complex, class I, B | 0.0304768 |
| CCNY | cyclin Y | 0.0303588 |
| RBM25 | RNA binding motif protein 25 | 0.0301979 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.204306 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.135425 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.13177 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0985713 |
| ATOSA | atos homolog A | -0.0889548 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0853251 |
| ANXA2 | annexin A2 | -0.0824844 |
| SVIL | supervillin | -0.0817316 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0752211 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0668746 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0633112 |
| PRKCA | protein kinase C, alpha | -0.0616425 |
| JMJD1C | jumonji domain containing 1C | -0.0607659 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0591936 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0577614 |
| INTS6 | integrator complex subunit 6 | -0.0576838 |
| USP53 | ubiquitin specific peptidase 53 | -0.057054 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.055315 |
| RORA | RAR-related orphan receptor A | -0.0537779 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0533844 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0533319 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0531521 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0530525 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0524586 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0519141 |
| EZR | ezrin | -0.051554 |
| SLTM | SAFB-like, transcription modulator | -0.0507181 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0504523 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.050144 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0500451 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0499848 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0494581 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.047908 |
| ZNF609 | zinc finger protein 609 | -0.0478598 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0466603 |
| PTK2 | protein tyrosine kinase 2 | -0.0465022 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0452998 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0450115 |
| CYTH1 | cytohesin 1 | -0.0441879 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0441868 |
| NABP1 | nucleic acid binding protein 1 | -0.0433067 |
| FBXO11 | F-box protein 11 | -0.0419748 |
| S100A10 | S100 calcium binding protein A10 | -0.0418552 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0417078 |
| ARF1 | ADP-ribosylation factor 1 | -0.0414526 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0408281 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0405247 |
| CERS6 | ceramide synthase 6 | -0.040463 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0398111 |
| MYO6 | myosin VI | -0.0390096 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0388371 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0382812 |
| TUSC3 | tumor suppressor candidate 3 | -0.0377214 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0372493 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0371613 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.036822 |
| FNIP1 | folliculin interacting protein 1 | -0.0367428 |
| FAM13B | family with sequence similarity 13, member B | -0.03645 |
| KYNU | kynureninase | -0.0364102 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0363949 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0363044 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.036052 |
| TXNRD1 | thioredoxin reductase 1 | -0.0358897 |
| OSMR | oncostatin M receptor | -0.0357706 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | -0.0357057 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0346063 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0345652 |
| TJP1 | tight junction protein 1 | -0.0342968 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.034288 |
| TXNIP | thioredoxin interacting protein | -0.0342439 |
| RPL35A | ribosomal protein L35a | -0.0335136 |
| MYO1E | myosin IE | -0.033372 |
| KLF6 | Kruppel-like factor 6 | -0.0331096 |
| TJP2 | tight junction protein 2 | -0.0329998 |
| VMP1 | vacuole membrane protein 1 | -0.0329983 |
| SETD5 | SET domain containing 5 | -0.0329818 |
| MED13L | mediator complex subunit 13-like | -0.0328083 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0322734 |
| FUS | FUS RNA binding protein | -0.0315505 |
| RAD51B | RAD51 paralog B | -0.0315354 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.031469 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.031459 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0311896 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0310273 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0303304 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0303175 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0297611 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0295832 |
| OXSR1 | oxidative stress responsive 1 | -0.0294024 |
| DENND5B | DENN/MADD domain containing 5B | -0.0293552 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0293506 |
| TAOK3 | TAO kinase 3 | -0.0293055 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0292705 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0291929 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0291291 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0290858 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0289872 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0286134 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0284033 |
| SRPK2 | SRSF protein kinase 2 | -0.0283887 |
