| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.220398 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.192392 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117577 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.11603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.106228 |
| FN1 | fibronectin 1 | 0.103213 |
| ASPH | aspartate beta-hydroxylase | 0.0976088 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0814338 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0628916 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0615567 |
| HMGB2 | high mobility group box 2 | 0.0600075 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0592261 |
| SQSTM1 | sequestosome 1 | 0.0591853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0521667 |
| LAMC2 | laminin, gamma 2 | 0.0503991 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.049355 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0456669 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0453536 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0453208 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0436461 |
| FAM13A | family with sequence similarity 13, member A | 0.0425371 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415142 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0395861 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0394124 |
| TFG | TRK-fused gene | 0.039183 |
| ANXA1 | annexin A1 | 0.0389692 |
| RPL11 | ribosomal protein L11 | 0.0369005 |
| RACK1 | receptor for activated C kinase 1 | 0.035376 |
| RPS3 | ribosomal protein S3 | 0.0349302 |
| MATR3 | matrin 3 | 0.0346667 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0341824 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0339941 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0339454 |
| ANXA5 | annexin A5 | 0.0328368 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0321164 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0310643 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0308674 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0308181 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0303839 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0293525 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0290292 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0289277 |
| RPL14 | ribosomal protein L14 | 0.0289093 |
| CCNL1 | cyclin L1 | 0.0287319 |
| RPLP0 | ribosomal protein, large, P0 | 0.0286907 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0284897 |
| ENO1 | enolase 1, (alpha) | 0.0281769 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0280109 |
| CENPF | centromere protein F, 350/400kDa | 0.0274944 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0270366 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0269961 |
| ANXA2 | annexin A2 | 0.0269033 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0266468 |
| LAMB3 | laminin, beta 3 | 0.0266038 |
| FAM162A | family with sequence similarity 162, member A | 0.0264958 |
| SET | SET nuclear proto-oncogene | 0.0261558 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0260712 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.026023 |
| RYBP | RING1 and YY1 binding protein | 0.0257297 |
| SPAG9 | sperm associated antigen 9 | 0.0257091 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0255427 |
| NCKAP1 | NCK-associated protein 1 | 0.024931 |
| USP3 | ubiquitin specific peptidase 3 | 0.0248777 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0246283 |
| YBX1 | Y box binding protein 1 | 0.0246025 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0242943 |
| RPL7 | ribosomal protein L7 | 0.0240823 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0239713 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0236664 |
| QKI | QKI, KH domain containing, RNA binding | 0.0236493 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0235639 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0233373 |
| LDHA | lactate dehydrogenase A | 0.0232292 |
| NUP58 | nucleoporin 58 | 0.0230761 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0230074 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0228424 |
| ATP13A3 | ATPase type 13A3 | 0.022591 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0221485 |
| SEPTIN7 | septin 7 | 0.0217847 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0214522 |
| ZNF292 | zinc finger protein 292 | 0.0213796 |
| MSN | moesin | 0.0212895 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.021198 |
| PAPOLA | poly(A) polymerase alpha | 0.0208565 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0208164 |
| SUCO | SUN domain containing ossification factor | 0.0206679 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0205116 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0204719 |
| RLF | rearranged L-myc fusion | 0.0203822 |
| RNF145 | ring finger protein 145 | 0.0200253 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0199305 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0198718 |
| PEG10 | paternally expressed 10 | 0.0197959 |
| CDC73 | cell division cycle 73 | 0.019775 |
| AREG | amphiregulin | 0.019664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0195769 |
| RPS12 | ribosomal protein S12 | 0.0194218 |
| RPS2 | ribosomal protein S2 | 0.0191284 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0191087 |
| SERINC1 | serine incorporator 1 | 0.018842 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.154983 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.137509 |
| ACTG1 | actin gamma 1 | -0.134353 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.132797 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131153 |
| FTL | ferritin, light polypeptide | -0.118809 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.113821 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.112897 |
| FBXO32 | F-box protein 32 | -0.103089 |
| EXT1 | exostosin glycosyltransferase 1 | -0.101779 |
| EFNA5 | ephrin-A5 | -0.0975507 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0974893 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0965925 |
| PTMA | prothymosin, alpha | -0.0901536 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0875629 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0658817 |
| RPL35A | ribosomal protein L35a | -0.0639776 |
| ERBIN | erbb2 interacting protein | -0.0639091 |
| TMEM165 | transmembrane protein 165 | -0.0633035 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0609932 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0607872 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0570141 |
| HLA-B | major histocompatibility complex, class I, B | -0.0556566 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0519391 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.050965 |
| RBM47 | RNA binding motif protein 47 | -0.050648 |
| MYO1E | myosin IE | -0.0503707 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.048863 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0464729 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0452347 |
| MX2 | MX dynamin-like GTPase 2 | -0.0446598 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0440342 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.043378 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0431353 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0421362 |
| LMO7 | LIM domain 7 | -0.0404359 |
| RNF213 | ring finger protein 213 | -0.0401914 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0394335 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0393899 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0391437 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0385662 |
| ATXN1 | ataxin 1 | -0.0385103 |
| FBXO34 | F-box protein 34 | -0.0382987 |
| HLA-A | major histocompatibility complex, class I, A | -0.038199 |
| FAM3C | family with sequence similarity 3, member C | -0.0380091 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0379022 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0377639 |
| RPL8 | ribosomal protein L8 | -0.037691 |
| WASF2 | WAS protein family, member 2 | -0.0376299 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0375743 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0374262 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.037271 |
| VEGFA | vascular endothelial growth factor A | -0.0372534 |
| FNIP1 | folliculin interacting protein 1 | -0.0368369 |
| S100A9 | S100 calcium binding protein A9 | -0.0365167 |
| ETV6 | ets variant 6 | -0.0364969 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0363674 |
| GOLGB1 | golgin B1 | -0.0355805 |
| NF1 | neurofibromin 1 | -0.0354956 |
| TPM4 | tropomyosin 4 | -0.0354001 |
| RCOR1 | REST corepressor 1 | -0.0351573 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0351009 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0349465 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0349176 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0343351 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0341858 |
| PTK2 | protein tyrosine kinase 2 | -0.0339296 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0338374 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0337335 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0335271 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0330065 |
| JUP | junction plakoglobin | -0.032994 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.032828 |
| VCL | vinculin | -0.0327607 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.03268 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0326258 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0325732 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0325665 |
| OCLN | occludin | -0.0325587 |
| MX1 | MX dynamin-like GTPase 1 | -0.0321637 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0321595 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0320559 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0320319 |
| MAP1B | microtubule-associated protein 1B | -0.0319333 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0319019 |
| SVIL | supervillin | -0.031723 |
| ATP11A | ATPase, class VI, type 11A | -0.0314681 |
| POTEF | POTE ankyrin domain family, member F | -0.0314593 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0313882 |
| RPS23 | ribosomal protein S23 | -0.0311873 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0311424 |
| RPS29 | ribosomal protein S29 | -0.0311377 |
| RAI14 | retinoic acid induced 14 | -0.0311371 |
| UBAP1 | ubiquitin associated protein 1 | -0.0311331 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0306113 |
| MAP4 | microtubule-associated protein 4 | -0.0304039 |
| EGFR | epidermal growth factor receptor | -0.0301835 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0301593 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0300837 |
| OSMR | oncostatin M receptor | -0.0299727 |
