| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0488408 |
| VCL | vinculin | 0.04005 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0366637 |
| MSN | moesin | 0.0331041 |
| CENPF | centromere protein F, 350/400kDa | 0.0324604 |
| ANXA1 | annexin A1 | 0.0322511 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0319591 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0319163 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0304875 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0290483 |
| SNX3 | sorting nexin 3 | 0.0289257 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0279719 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0272385 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0271537 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0270616 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.027009 |
| FAT1 | FAT atypical cadherin 1 | 0.0268355 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0264947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0254049 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.0252593 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0241502 |
| CFL2 | cofilin 2 (muscle) | 0.0237511 |
| RPL3 | ribosomal protein L3 | 0.0237407 |
| EFNA5 | ephrin-A5 | 0.0229026 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0223206 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0221759 |
| TRIP11 | thyroid hormone receptor interactor 11 | 0.0221491 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0220842 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0220367 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0207722 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0206057 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.020561 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0205286 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0202061 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0200795 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0198667 |
| RNF11 | ring finger protein 11 | 0.0195004 |
| ERBIN | erbb2 interacting protein | 0.0193863 |
| CEP135 | centrosomal protein 135kDa | 0.0191341 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0190569 |
| HTATSF1 | HIV-1 Tat specific factor 1 | 0.0190508 |
| ANLN | anillin, actin binding protein | 0.0190029 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0188029 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0187702 |
| KIF1B | kinesin family member 1B | 0.0187172 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.018675 |
| PFN1 | profilin 1 | 0.0186033 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0185006 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0184578 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0181696 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0181677 |
| RPS14 | ribosomal protein S14 | 0.0179782 |
| DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.0179009 |
| POTEF | POTE ankyrin domain family, member F | 0.0178921 |
| POSTN | periostin, osteoblast specific factor | 0.0176867 |
| TLK2 | tousled-like kinase 2 | 0.0176614 |
| CCNA2 | cyclin A2 | 0.0175235 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0173916 |
| MEF2A | myocyte enhancer factor 2A | 0.0173209 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0171787 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0171705 |
| SFSWAP | splicing factor, suppressor of white-apricot family | 0.0171367 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0169898 |
| CEP112 | centrosomal protein 112kDa | 0.0168732 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0167689 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0167118 |
| SIK3 | SIK family kinase 3 | 0.0166814 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0166803 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0166294 |
| BRD2 | bromodomain containing 2 | 0.0165371 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.0164859 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0164809 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.016474 |
| MINK1 | misshapen-like kinase 1 | 0.0164563 |
| SEPTIN2 | septin 2 | 0.0164135 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.016382 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0163771 |
| STX5 | syntaxin 5 | 0.0163495 |
| EEIG2 | EEIG family member 2 | 0.0163068 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0162468 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 | 0.016157 |
| ZYX | zyxin | 0.0161524 |
| PCDH18 | protocadherin 18 | 0.0161134 |
| DIAPH3 | diaphanous-related formin 3 | 0.0161124 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0160678 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0160521 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | 0.0159261 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0159012 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0158401 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0158364 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.0157447 |
| NMD3 | NMD3 ribosome export adaptor | 0.0156769 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.0156438 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0156335 |
| CAB39 | calcium binding protein 39 | 0.0156092 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0155614 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0155426 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0155311 |
| RREB1 | ras responsive element binding protein 1 | 0.0155196 |
| STX16 | syntaxin 16 | 0.0154913 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.164299 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.147847 |
| COL11A1 | collagen, type XI, alpha 1 | -0.122797 |
| HDAC9 | histone deacetylase 9 | -0.118243 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113976 |
| GPC3 | glypican 3 | -0.10342 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0993578 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0989989 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0949005 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0944277 |
| PEG10 | paternally expressed 10 | -0.0918544 |
| VIM | vimentin | -0.0896441 |
| RPS16 | ribosomal protein S16 | -0.0759741 |
| THBS1 | thrombospondin 1 | -0.0758235 |
| CADM2 | cell adhesion molecule 2 | -0.0724956 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0690715 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0680047 |
| PTMA | prothymosin, alpha | -0.0663498 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0660109 |
| SPAG9 | sperm associated antigen 9 | -0.0647243 |
| RPS27A | ribosomal protein S27a | -0.0616287 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0613496 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0607772 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0595134 |
| AHNAK | AHNAK nucleoprotein | -0.0589182 |
| JMJD1C | jumonji domain containing 1C | -0.0557746 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0554125 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0552712 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0543957 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.052409 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.052187 |
| TENM3 | teneurin transmembrane protein 3 | -0.0518575 |
| SRP54 | signal recognition particle 54kDa | -0.0510602 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0507386 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0504914 |
| EMP1 | epithelial membrane protein 1 | -0.0503805 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.049311 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0482599 |
| LRRC4C | leucine rich repeat containing 4C | -0.0482556 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0482039 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0469839 |
| ITGAV | integrin, alpha V | -0.0467937 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0457263 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0453166 |
| ACTG1 | actin gamma 1 | -0.0450366 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.043377 |
| SYT1 | synaptotagmin I | -0.0433585 |
| COL5A2 | collagen, type V, alpha 2 | -0.0433205 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0425812 |
| UPP1 | uridine phosphorylase 1 | -0.0419965 |
| TFRC | transferrin receptor | -0.0418433 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0416417 |
| RBM39 | RNA binding motif protein 39 | -0.0407467 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0405638 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0404681 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0397827 |
| PHIP | pleckstrin homology domain interacting protein | -0.03948 |
| UBC | ubiquitin C | -0.0387715 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.038491 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0382265 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0381006 |
| MED13L | mediator complex subunit 13-like | -0.037808 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0377323 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0366305 |
| RPS8 | ribosomal protein S8 | -0.0365695 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0359498 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0358491 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0357773 |
| CDK6 | cyclin-dependent kinase 6 | -0.0356724 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0350914 |
| USP53 | ubiquitin specific peptidase 53 | -0.0350384 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347812 |
| SHROOM3 | shroom family member 3 | -0.0340101 |
| ACTN4 | actinin, alpha 4 | -0.0338864 |
| PLPP1 | phospholipid phosphatase 1 | -0.0335272 |
| MYO10 | myosin X | -0.0325648 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0323159 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0320432 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.031933 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0314891 |
| RPL5 | ribosomal protein L5 | -0.030885 |
| FBXO17 | F-box protein 17 | -0.0307708 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0304721 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0303017 |
| RPL37 | ribosomal protein L37 | -0.0302958 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0301399 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | -0.0300403 |
| RPL12 | ribosomal protein L12 | -0.0299129 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0297908 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0296841 |
| MAP4 | microtubule-associated protein 4 | -0.0296401 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0295808 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0295356 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0289027 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0286526 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0285951 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0285827 |
| IGF2R | insulin-like growth factor 2 receptor | -0.028548 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0284741 |
| APP | amyloid beta (A4) precursor protein | -0.0283958 |
