| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0700491 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0541743 |
| MSN | moesin | 0.0443058 |
| ATP13A3 | ATPase type 13A3 | 0.0399951 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0352908 |
| IL6 | interleukin 6 | 0.032706 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.032589 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.032193 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0317733 |
| RNF145 | ring finger protein 145 | 0.0311271 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0286959 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0282949 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0278268 |
| KAZN | kazrin, periplakin interacting protein | 0.027349 |
| NBAS | neuroblastoma amplified sequence | 0.0262326 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.025928 |
| NAV2 | neuron navigator 2 | 0.0257443 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0256363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0254107 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0252334 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0242498 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.023897 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0227432 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0223062 |
| EGFR | epidermal growth factor receptor | 0.0219365 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0214865 |
| AFDN | afadin, adherens junction formation factor | 0.0212338 |
| FLNB | filamin B, beta | 0.021191 |
| NKTR | natural killer cell triggering receptor | 0.0205017 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0202833 |
| SNX13 | sorting nexin 13 | 0.020231 |
| CCNL1 | cyclin L1 | 0.0200516 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0196059 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0195936 |
| ITGA6 | integrin, alpha 6 | 0.0193507 |
| RNF213 | ring finger protein 213 | 0.0192484 |
| GOLGA4 | golgin A4 | 0.0192188 |
| EFNA5 | ephrin-A5 | 0.0187934 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0182519 |
| RBM26 | RNA binding motif protein 26 | 0.0180849 |
| EZR | ezrin | 0.0180057 |
| LIMA1 | LIM domain and actin binding 1 | 0.0179887 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0179087 |
| LSAMP | limbic system-associated membrane protein | 0.0179017 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0176782 |
| MICU1 | mitochondrial calcium uptake 1 | 0.017302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0172788 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0172704 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0171336 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0170707 |
| ARRDC3 | arrestin domain containing 3 | 0.0168198 |
| DENND4C | DENN/MADD domain containing 4C | 0.0167649 |
| SEC24B | SEC24 family member B | 0.0167378 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0167219 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0166194 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0165854 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | 0.0165708 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0164023 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0163652 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0163229 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0163024 |
| METTL15 | methyltransferase like 15 | 0.0162605 |
| PDE8A | phosphodiesterase 8A | 0.016253 |
| TPM3 | tropomyosin 3 | 0.0161913 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.016186 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.016162 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0160044 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0159035 |
| SRPK2 | SRSF protein kinase 2 | 0.015882 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0158177 |
| SPNS1 | spinster homolog 1 (Drosophila) | 0.0157906 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0156906 |
| TNPO3 | transportin 3 | 0.0156889 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.015591 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0155124 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.015511 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0154335 |
| HYOU1 | hypoxia up-regulated 1 | 0.0148824 |
| UBXN4 | UBX domain protein 4 | 0.0147595 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.014667 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0146548 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0146435 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.014615 |
| RNF216 | ring finger protein 216 | 0.0145459 |
| SPPL3 | signal peptide peptidase like 3 | 0.0144351 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.014398 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0143695 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0143369 |
| SETX | senataxin | 0.0143186 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.01428 |
| MMP12 | matrix metallopeptidase 12 | 0.0142082 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0141909 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0141759 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0141492 |
| RBM33 | RNA binding motif protein 33 | 0.0140761 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0140414 |
| PTK2 | protein tyrosine kinase 2 | 0.0140375 |
| RUNX1 | runt-related transcription factor 1 | 0.014031 |
| THOC2 | THO complex 2 | 0.0140246 |
| CEP350 | centrosomal protein 350kDa | 0.013825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.266605 |
| MT2A | metallothionein 2A | -0.133694 |
| TMSB10 | thymosin beta 10 | -0.0993589 |
| HLA-B | major histocompatibility complex, class I, B | -0.0922645 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.090448 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0842202 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0717471 |
| VIM | vimentin | -0.0687521 |
| LOXL2 | lysyl oxidase-like 2 | -0.0634639 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0605311 |
| COL1A1 | collagen, type I, alpha 1 | -0.0602548 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0575992 |
| PTMA | prothymosin, alpha | -0.0572127 |
| FN1 | fibronectin 1 | -0.0557772 |
| HLA-C | major histocompatibility complex, class I, C | -0.0541875 |
| SDC4 | syndecan 4 | -0.052078 |
| COL1A2 | collagen, type I, alpha 2 | -0.0482857 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0470149 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0468668 |
| LOX | lysyl oxidase | -0.0468378 |
| PRSS23 | protease, serine, 23 | -0.0464172 |
| HLA-A | major histocompatibility complex, class I, A | -0.0456843 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0447747 |
| HDLBP | high density lipoprotein binding protein | -0.0393884 |
| CD44 | CD44 molecule (Indian blood group) | -0.0393155 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0391381 |
| S100A10 | S100 calcium binding protein A10 | -0.038606 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0379104 |
| B2M | beta-2-microglobulin | -0.0378003 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0374101 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0370862 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0369375 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0347436 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0342598 |
| VCL | vinculin | -0.0342385 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0333809 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0331969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.032906 |
| ACTG1 | actin gamma 1 | -0.0317657 |
| SEC24D | SEC24 family member D | -0.0313562 |
| CAVIN1 | caveolae associated protein 1 | -0.0306809 |
| CALU | calumenin | -0.0301234 |
| ANXA2 | annexin A2 | -0.0299706 |
| RPL28 | ribosomal protein L28 | -0.0285593 |
| BSG | basigin (Ok blood group) | -0.0284658 |
| GNAS | GNAS complex locus | -0.028143 |
| LDHA | lactate dehydrogenase A | -0.028051 |
| HMGB1 | high mobility group box 1 | -0.0280489 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0278603 |
| FTL | ferritin, light polypeptide | -0.0278377 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0277433 |
| NAV1 | neuron navigator 1 | -0.0277003 |
| FUS | FUS RNA binding protein | -0.0274889 |
| AHNAK | AHNAK nucleoprotein | -0.027248 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0269615 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0268657 |
| CLIC4 | chloride intracellular channel 4 | -0.0263971 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0263604 |
| TUBB | tubulin, beta class I | -0.0260904 |
| MYOF | myoferlin | -0.0255352 |
| RPS23 | ribosomal protein S23 | -0.0255159 |
| RPL34 | ribosomal protein L34 | -0.0255025 |
| ARF1 | ADP-ribosylation factor 1 | -0.0253443 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.025236 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0248554 |
| HM13 | histocompatibility (minor) 13 | -0.0248113 |
| CCNI | cyclin I | -0.0246115 |
| MT1X | metallothionein 1X | -0.0244559 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0243347 |
| MAP1B | microtubule-associated protein 1B | -0.0243013 |
| NDRG1 | N-myc downstream regulated 1 | -0.0242916 |
| S100A9 | S100 calcium binding protein A9 | -0.0241453 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0239684 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0239579 |
| UBC | ubiquitin C | -0.0236944 |
| THY1 | Thy-1 cell surface antigen | -0.0235873 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0234214 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231618 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0226013 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0223318 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0222119 |
| KLHDC10 | kelch domain containing 10 | -0.0220932 |
| SRP54 | signal recognition particle 54kDa | -0.0218549 |
| EMP1 | epithelial membrane protein 1 | -0.0217232 |
| ASPH | aspartate beta-hydroxylase | -0.021299 |
| ZNF217 | zinc finger protein 217 | -0.0210521 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0208533 |
| TPM4 | tropomyosin 4 | -0.0208208 |
| OGA | O-GlcNAcase | -0.0208042 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0207079 |
| POTEF | POTE ankyrin domain family, member F | -0.0205585 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0203584 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0203311 |
| PMM2 | phosphomannomutase 2 | -0.020256 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0202458 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.020205 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0200453 |
| RBM39 | RNA binding motif protein 39 | -0.0198975 |
| GLIS3 | GLIS family zinc finger 3 | -0.0195814 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0195235 |