| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rosiglitazone perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rosiglitazone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.102773 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0862256 |
| GOLGA4 | golgin A4 | 0.0814387 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0755455 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0622581 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0616884 |
| ZNF292 | zinc finger protein 292 | 0.060154 |
| CENPF | centromere protein F, 350/400kDa | 0.0592913 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0504244 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0422996 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0416502 |
| TXNRD1 | thioredoxin reductase 1 | 0.039002 |
| ANLN | anillin, actin binding protein | 0.038164 |
| CENPE | centromere protein E, 312kDa | 0.0375243 |
| SET | SET nuclear proto-oncogene | 0.037111 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0365114 |
| YAP1 | Yes-associated protein 1 | 0.0363214 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0358791 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0342344 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.033852 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0335637 |
| HELZ | helicase with zinc finger | 0.0334366 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0333383 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0330029 |
| KIF5B | kinesin family member 5B | 0.0329826 |
| SGO2 | shugoshin 2 | 0.032723 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0313373 |
| ECT2 | epithelial cell transforming 2 | 0.0312065 |
| TPX2 | TPX2, microtubule-associated | 0.030307 |
| MSN | moesin | 0.0301489 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0299348 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0297936 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0297348 |
| SEC24A | SEC24 family member A | 0.0282942 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0279751 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277801 |
| HMGB2 | high mobility group box 2 | 0.0275732 |
| COG6 | component of oligomeric golgi complex 6 | 0.0275534 |
| NUP153 | nucleoporin 153kDa | 0.0269822 |
| COPA | coatomer protein complex, subunit alpha | 0.026856 |
| MORF4L2 | mortality factor 4 like 2 | 0.0267058 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0263828 |
| NUP58 | nucleoporin 58 | 0.0262745 |
| COG5 | component of oligomeric golgi complex 5 | 0.0255695 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0253407 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0245493 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0242466 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0240371 |
| SNX14 | sorting nexin 14 | 0.023989 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0239469 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.023542 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0235091 |
| MATR3 | matrin 3 | 0.0235073 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0234827 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0234717 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0234359 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0231356 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0229726 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0229272 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0228961 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0222754 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.022258 |
| CCNL1 | cyclin L1 | 0.0222048 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0221693 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.022101 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0220833 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0220641 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0219304 |
| TFG | TRK-fused gene | 0.0219007 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0218127 |
| MKI67 | marker of proliferation Ki-67 | 0.0217632 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0217047 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0216806 |
| ANXA1 | annexin A1 | 0.0216301 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0215649 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0215596 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0214372 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0214154 |
| FANCI | Fanconi anemia, complementation group I | 0.0213689 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0213157 |
| STK38 | serine/threonine kinase 38 | 0.021182 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0210119 |
| TRAM1 | translocation associated membrane protein 1 | 0.0210017 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0209344 |
| DTNA | dystrobrevin, alpha | 0.0208201 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.0208193 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.020818 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0207844 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0206148 |
| CEP250 | centrosomal protein 250kDa | 0.0204942 |
| WDR26 | WD repeat domain 26 | 0.0204721 |
| PNN | pinin, desmosome associated protein | 0.0204198 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0203087 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0202748 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0202528 |
| CHMP4B | charged multivesicular body protein 4B | 0.0201231 |
| DIAPH3 | diaphanous-related formin 3 | 0.0201069 |
| ARRDC3 | arrestin domain containing 3 | 0.0200756 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0200074 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0199942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261538 |
| VIM | vimentin | -0.16155 |
| TMSB10 | thymosin beta 10 | -0.154251 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.123508 |
| PTMA | prothymosin, alpha | -0.0887507 |
| PRKCA | protein kinase C, alpha | -0.0883371 |
| HMGA2 | high mobility group AT-hook 2 | -0.0841866 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0767443 |
| IGF2 | insulin-like growth factor 2 | -0.0679773 |
| CD44 | CD44 molecule (Indian blood group) | -0.0653241 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0624484 |
| RPL35A | ribosomal protein L35a | -0.0622684 |
| GNAS | GNAS complex locus | -0.0607338 |
| SDC4 | syndecan 4 | -0.0602396 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0591439 |
| RPLP1 | ribosomal protein, large, P1 | -0.0587179 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0574378 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0545253 |
| PRSS23 | protease, serine, 23 | -0.0534477 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0534184 |
| OSMR | oncostatin M receptor | -0.0533912 |
| ANGPTL4 | angiopoietin-like 4 | -0.0529191 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.051162 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0498966 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0495939 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0490401 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0488752 |
| LDHA | lactate dehydrogenase A | -0.0481875 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0479674 |
| ATXN1 | ataxin 1 | -0.0457689 |
| RAI14 | retinoic acid induced 14 | -0.045257 |
| RIGI | RNA sensor RIG-I | -0.0451866 |
| VCL | vinculin | -0.0448888 |
| PTK2 | protein tyrosine kinase 2 | -0.0447332 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0443554 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0443452 |
| RPS13 | ribosomal protein S13 | -0.0437855 |
| HLA-B | major histocompatibility complex, class I, B | -0.0417865 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0414413 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0398704 |
| EGR1 | early growth response 1 | -0.0398571 |
| FMNL2 | formin-like 2 | -0.03944 |
| NDRG1 | N-myc downstream regulated 1 | -0.0391887 |
| SMYD3 | SET and MYND domain containing 3 | -0.0389842 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0387697 |
| FLNB | filamin B, beta | -0.0387146 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0386902 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0378226 |
| S100A10 | S100 calcium binding protein A10 | -0.0377732 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0368613 |
| SVIL | supervillin | -0.0364805 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0355653 |
| PKM | pyruvate kinase, muscle | -0.035472 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0352488 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0351753 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.034806 |
| RPL15 | ribosomal protein L15 | -0.034762 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0346566 |
| CAVIN1 | caveolae associated protein 1 | -0.0346461 |
| MYO9B | myosin IXB | -0.0342505 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0340692 |
| B2M | beta-2-microglobulin | -0.0337794 |
| H3-3B | H3.3 histone B | -0.0337487 |
| MAP1B | microtubule-associated protein 1B | -0.0332168 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0330751 |
| IER3 | immediate early response 3 | -0.0323212 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0323063 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0318889 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0317361 |
| ACTG1 | actin gamma 1 | -0.0317348 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0316648 |
| INTS6 | integrator complex subunit 6 | -0.0314812 |
| FMN1 | formin 1 | -0.0313695 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0312678 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0309429 |
| ZNF609 | zinc finger protein 609 | -0.0307605 |
| S100A9 | S100 calcium binding protein A9 | -0.0306312 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0303239 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0298578 |
| RNF213 | ring finger protein 213 | -0.0297643 |
| RANBP17 | RAN binding protein 17 | -0.0295391 |
| DST | dystonin | -0.0294898 |
| POTEF | POTE ankyrin domain family, member F | -0.0291289 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0288794 |
| DENND5B | DENN/MADD domain containing 5B | -0.0288346 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.028727 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0285404 |
| RPL37 | ribosomal protein L37 | -0.0281185 |
| NALCN | sodium leak channel, non selective | -0.027682 |
| HLA-A | major histocompatibility complex, class I, A | -0.0275604 |
| PCED1B | PC-esterase domain containing 1B | -0.0275279 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0274855 |
| HMGA1 | high mobility group AT-hook 1 | -0.027302 |
| AHNAK | AHNAK nucleoprotein | -0.0272557 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0271414 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0270163 |
| MT2A | metallothionein 2A | -0.0269823 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0268581 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.026838 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0267058 |
