| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Roxadustat perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Roxadustat_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.121445 |
| FAM13A | family with sequence similarity 13, member A | 0.117922 |
| HELZ | helicase with zinc finger | 0.112038 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.100498 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0946642 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0926587 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0892607 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0865705 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0835949 |
| MEF2A | myocyte enhancer factor 2A | 0.0793712 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0672866 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0623333 |
| WDR45B | WD repeat domain 45B | 0.0620421 |
| PCBP2 | poly(rC) binding protein 2 | 0.0603125 |
| AHNAK | AHNAK nucleoprotein | 0.0600639 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0599434 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.058847 |
| DTNA | dystrobrevin, alpha | 0.0574132 |
| DST | dystonin | 0.056719 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0552062 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0545013 |
| PGK1 | phosphoglycerate kinase 1 | 0.0525538 |
| ENO1 | enolase 1, (alpha) | 0.0519961 |
| SMAD3 | SMAD family member 3 | 0.0509358 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0509154 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0506005 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0497752 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0497234 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0495352 |
| OGA | O-GlcNAcase | 0.0494666 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0493121 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0489754 |
| MSI2 | musashi RNA-binding protein 2 | 0.0480817 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0478938 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0475816 |
| TRIB2 | tribbles pseudokinase 2 | 0.0470637 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0455727 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0452067 |
| PKM | pyruvate kinase, muscle | 0.0439481 |
| RNF145 | ring finger protein 145 | 0.0429046 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.042543 |
| COPA | coatomer protein complex, subunit alpha | 0.0423389 |
| SPAG9 | sperm associated antigen 9 | 0.0421701 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0420886 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0408052 |
| SEPTIN9 | septin 9 | 0.0404059 |
| CADM1 | cell adhesion molecule 1 | 0.0402783 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0401455 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0396285 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0393687 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0393317 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393161 |
| PTK2 | protein tyrosine kinase 2 | 0.0389938 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0388201 |
| RYBP | RING1 and YY1 binding protein | 0.0388004 |
| RLF | rearranged L-myc fusion | 0.0386479 |
| MED13 | mediator complex subunit 13 | 0.0383127 |
| LDHA | lactate dehydrogenase A | 0.0377306 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0372194 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0371352 |
| ZNF292 | zinc finger protein 292 | 0.0368664 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0367691 |
| SETD5 | SET domain containing 5 | 0.0364644 |
| PHIP | pleckstrin homology domain interacting protein | 0.0364403 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0363502 |
| MED13L | mediator complex subunit 13-like | 0.0358885 |
| AFDN | afadin, adherens junction formation factor | 0.0358529 |
| RTN4 | reticulon 4 | 0.0357711 |
| RBM39 | RNA binding motif protein 39 | 0.0354446 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.034614 |
| FLNB | filamin B, beta | 0.0343008 |
| APP | amyloid beta (A4) precursor protein | 0.0342224 |
| CCNL1 | cyclin L1 | 0.0336085 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0335093 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0334339 |
| ASPH | aspartate beta-hydroxylase | 0.0333674 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0333526 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0332018 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0329205 |
| PTMA | prothymosin, alpha | 0.0328429 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0328163 |
| TFG | TRK-fused gene | 0.0325697 |
| PCBP3 | poly(rC) binding protein 3 | 0.032494 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0312673 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0310184 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0310035 |
| RCOR1 | REST corepressor 1 | 0.0305813 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0304988 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0304926 |
| RIOK3 | RIO kinase 3 | 0.0303754 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0303071 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0298547 |
| SUCO | SUN domain containing ossification factor | 0.0297062 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0296384 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0296227 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0295498 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0294815 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0294154 |
| NUP58 | nucleoporin 58 | 0.0294042 |
| TLK2 | tousled-like kinase 2 | 0.0293743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.237087 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.144345 |
| SYT1 | synaptotagmin I | -0.0892958 |
| NRG1 | neuregulin 1 | -0.0849565 |
| LSAMP | limbic system-associated membrane protein | -0.0826591 |
| BPTF | bromodomain PHD finger transcription factor | -0.0699249 |
| RPLP1 | ribosomal protein, large, P1 | -0.0665632 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0580732 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0536386 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.050692 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0503775 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0477801 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0468737 |
| PLAT | plasminogen activator, tissue | -0.0459787 |
| KLHL13 | kelch-like family member 13 | -0.0453951 |
| RPL23 | ribosomal protein L23 | -0.042793 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0394516 |
| NCAM2 | neural cell adhesion molecule 2 | -0.039288 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0387894 |
| CADM2 | cell adhesion molecule 2 | -0.0360372 |
| MEIS2 | Meis homeobox 2 | -0.035691 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0348021 |
| RPL38 | ribosomal protein L38 | -0.0344149 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0343739 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0340744 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0329429 |
| ZNF804A | zinc finger protein 804A | -0.0324644 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0323608 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.032192 |
| PCDH9 | protocadherin 9 | -0.0319855 |
| GPC5 | glypican 5 | -0.031909 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0310173 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0309159 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0294762 |
| FMN1 | formin 1 | -0.0294647 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0293373 |
| DPH6 | diphthamine biosynthesis 6 | -0.0288519 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286244 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0286243 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0281642 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0279467 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0272391 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.027238 |
| PCNX4 | pecanex 4 | -0.0270029 |
| MAP1B | microtubule-associated protein 1B | -0.0268414 |
| TENM4 | teneurin transmembrane protein 4 | -0.0264654 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0263624 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0260402 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0259837 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0258253 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0256235 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0256185 |
| TBX2 | T-box 2 | -0.0252294 |
| STXBP4 | syntaxin binding protein 4 | -0.0252039 |
| CEP95 | centrosomal protein 95kDa | -0.0250333 |
| PHOX2B | paired-like homeobox 2b | -0.0248369 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0247373 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0242313 |
| PLPP1 | phospholipid phosphatase 1 | -0.0241183 |
| KLF6 | Kruppel-like factor 6 | -0.0239649 |
| CDK12 | cyclin-dependent kinase 12 | -0.0238519 |
| CALD1 | caldesmon 1 | -0.0235261 |
| COL1A1 | collagen, type I, alpha 1 | -0.0230958 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0228191 |
| GLCCI1 | glucocorticoid induced 1 | -0.0228124 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0226547 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0225864 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.022387 |
| TLE4 | transducin-like enhancer of split 4 | -0.0219994 |
| VIM | vimentin | -0.0219246 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0218286 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.021389 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0212279 |
| GATA3 | GATA binding protein 3 | -0.0208686 |
| RPL19 | ribosomal protein L19 | -0.020851 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0205236 |
| H3-3B | H3.3 histone B | -0.020481 |
| COL3A1 | collagen, type III, alpha 1 | -0.020425 |
| TRIM56 | tripartite motif containing 56 | -0.0202659 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.020091 |
| FTL | ferritin, light polypeptide | -0.0199358 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0198122 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0198064 |
| RPL34 | ribosomal protein L34 | -0.0196557 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0196555 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0195774 |
| BMERB1 | bMERB domain containing 1 | -0.0194788 |
| RPS6 | ribosomal protein S6 | -0.0194497 |
| RPL37 | ribosomal protein L37 | -0.0194193 |
| NRP1 | neuropilin 1 | -0.0194149 |
| MX2 | MX dynamin-like GTPase 2 | -0.0193561 |
| STC1 | stanniocalcin 1 | -0.0192549 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0190888 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0189804 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0186294 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0184207 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0183519 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | -0.0183241 |
| KIF21A | kinesin family member 21A | -0.0181004 |
| FOXN3 | forkhead box N3 | -0.0179958 |
