| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Roxadustat perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Roxadustat_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.158975 |
| LDHA | lactate dehydrogenase A | 0.122642 |
| PTMA | prothymosin, alpha | 0.0949727 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0874987 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0852552 |
| AHNAK | AHNAK nucleoprotein | 0.0821916 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0688006 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0593429 |
| ATP13A3 | ATPase type 13A3 | 0.0592976 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0592664 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0589351 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0586961 |
| TMSB10 | thymosin beta 10 | 0.0581564 |
| RBM39 | RNA binding motif protein 39 | 0.0545621 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0545326 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0540898 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0511271 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0506823 |
| CAPRIN2 | caprin family member 2 | 0.0503762 |
| SMYD3 | SET and MYND domain containing 3 | 0.0495827 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0493082 |
| YBX3 | Y box binding protein 3 | 0.0487571 |
| ECT2 | epithelial cell transforming 2 | 0.0485479 |
| ENO1 | enolase 1, (alpha) | 0.0484341 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0424565 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0421583 |
| RPL4 | ribosomal protein L4 | 0.0418101 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0416002 |
| CANX | calnexin | 0.0414212 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0413934 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411625 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0410921 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0408133 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0407325 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0400685 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0388689 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0378921 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0377501 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0375011 |
| NUP58 | nucleoporin 58 | 0.0372279 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0371065 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0366375 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0362802 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0361783 |
| CD44 | CD44 molecule (Indian blood group) | 0.0358566 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0358363 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0345234 |
| MAP4 | microtubule-associated protein 4 | 0.0345063 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0343534 |
| FMNL2 | formin-like 2 | 0.0332508 |
| PDE8A | phosphodiesterase 8A | 0.0329605 |
| ATXN2L | ataxin 2-like | 0.0329265 |
| PGK1 | phosphoglycerate kinase 1 | 0.0323587 |
| FLNB | filamin B, beta | 0.0319377 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0319071 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0317716 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0309787 |
| DNER | delta/notch-like EGF repeat containing | 0.0309232 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0306786 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0304069 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0303172 |
| DTNA | dystrobrevin, alpha | 0.0302482 |
| RAD51B | RAD51 paralog B | 0.0299171 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0298883 |
| CFH | complement factor H | 0.0290591 |
| NGLY1 | N-glycanase 1 | 0.0290079 |
| PCBP2 | poly(rC) binding protein 2 | 0.0289374 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0288622 |
| PKM | pyruvate kinase, muscle | 0.0288418 |
| ATXN1 | ataxin 1 | 0.0287362 |
| CALR | calreticulin | 0.0278529 |
| RPS17 | ribosomal protein S17 | 0.0277362 |
| JMJD1C | jumonji domain containing 1C | 0.0275062 |
| SEC24A | SEC24 family member A | 0.0274919 |
| SPAG9 | sperm associated antigen 9 | 0.0269986 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0268106 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0266611 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0265566 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.02655 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0263634 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0263065 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0263009 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0262489 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0261978 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | 0.0259929 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0259298 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0257725 |
| USP3 | ubiquitin specific peptidase 3 | 0.0256611 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.02565 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0255967 |
| ANKRD11 | ankyrin repeat domain 11 | 0.025552 |
| PHF21A | PHD finger protein 21A | 0.0254456 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0253614 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0252592 |
| HELZ | helicase with zinc finger | 0.0250654 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0248975 |
| SEPTIN10 | septin 10 | 0.0248613 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0248537 |
| ZNF638 | zinc finger protein 638 | 0.0246423 |
| RLF | rearranged L-myc fusion | 0.0245992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.26179 |
| RPLP1 | ribosomal protein, large, P1 | -0.0728025 |
| RPLP2 | ribosomal protein, large, P2 | -0.0371353 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0362301 |
| FTL | ferritin, light polypeptide | -0.0321205 |
| ASPH | aspartate beta-hydroxylase | -0.0318229 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.030403 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0300799 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0299506 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0295349 |
| CFDP1 | craniofacial development protein 1 | -0.0288322 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0287438 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0281877 |
| RPL23 | ribosomal protein L23 | -0.0278918 |
| OSMR | oncostatin M receptor | -0.0271694 |
| SETD5 | SET domain containing 5 | -0.0269388 |
| OLA1 | Obg-like ATPase 1 | -0.0266485 |
| IGF2 | insulin-like growth factor 2 | -0.0266166 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0255684 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0253967 |
| FN1 | fibronectin 1 | -0.0253528 |
| RPL35A | ribosomal protein L35a | -0.025339 |
| TCF12 | transcription factor 12 | -0.0248594 |
| TUBB | tubulin, beta class I | -0.0248572 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0246347 |
| RASAL2 | RAS protein activator like 2 | -0.0239112 |
| PRKD3 | protein kinase D3 | -0.0237891 |
| RPL12 | ribosomal protein L12 | -0.023696 |
| ITGAV | integrin, alpha V | -0.0235545 |
| TUT4 | terminal uridylyl transferase 4 | -0.0233809 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0233197 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.023282 |
| ZNF609 | zinc finger protein 609 | -0.0231608 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0229182 |
| BCL2L1 | BCL2-like 1 | -0.0227805 |
| CEP350 | centrosomal protein 350kDa | -0.0225574 |
| GPHN | gephyrin | -0.0225324 |
| NUCB2 | nucleobindin 2 | -0.0224904 |
| EFCAB11 | EF-hand calcium binding domain 11 | -0.0223141 |
| NF1 | neurofibromin 1 | -0.0222731 |
| RPS13 | ribosomal protein S13 | -0.0220998 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0219118 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0215409 |
| EGFR | epidermal growth factor receptor | -0.0211656 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0211298 |
| GLCCI1 | glucocorticoid induced 1 | -0.0210729 |
| RPL36A | ribosomal protein L36a | -0.0209075 |
| SSH2 | slingshot protein phosphatase 2 | -0.0206977 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0203278 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0199523 |
| RPL38 | ribosomal protein L38 | -0.019921 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0198473 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -0.0197185 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0196203 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0196144 |
| TCERG1 | transcription elongation regulator 1 | -0.0195864 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0195398 |
| HOMER2 | homer scaffolding protein 2 | -0.0195233 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0194237 |
| RAB28 | RAB28, member RAS oncogene family | -0.0193782 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0193415 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0193213 |
| PHF20 | PHD finger protein 20 | -0.0192669 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0191906 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0191796 |
| ETV1 | ets variant 1 | -0.0190325 |
| PMP22 | peripheral myelin protein 22 | -0.0189825 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.0189529 |
| FUS | FUS RNA binding protein | -0.0189378 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.018908 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0188797 |
| PHIP | pleckstrin homology domain interacting protein | -0.0188446 |
| SRP54 | signal recognition particle 54kDa | -0.0188148 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0187983 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0187218 |
| GALK2 | galactokinase 2 | -0.0186777 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0185755 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.018546 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0185388 |
| GAN | gigaxonin | -0.0185133 |
| STC1 | stanniocalcin 1 | -0.0184986 |
| GUK1 | guanylate kinase 1 | -0.0184008 |
| VMP1 | vacuole membrane protein 1 | -0.018397 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.0183306 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0182569 |
| NDRG1 | N-myc downstream regulated 1 | -0.018174 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0180813 |
| JUN | jun proto-oncogene | -0.0180194 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0177577 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0177041 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.017579 |
| TES | testin LIM domain protein | -0.0174566 |
| SYTL2 | synaptotagmin-like 2 | -0.017382 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0173781 |
| RAB33B | RAB33B, member RAS oncogene family | -0.0173699 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0172971 |
| TSG101 | tumor susceptibility 101 | -0.0172889 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0172146 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.0172043 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0171195 |
