| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.197863 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.151694 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.12299 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0905092 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0903612 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0719084 |
| CD44 | CD44 molecule (Indian blood group) | 0.0663986 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0556777 |
| NAV1 | neuron navigator 1 | 0.0550567 |
| FBN1 | fibrillin 1 | 0.0534572 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0530708 |
| PODXL | podocalyxin-like | 0.0522558 |
| FLNB | filamin B, beta | 0.0497178 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.046688 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0453904 |
| LOXL2 | lysyl oxidase-like 2 | 0.0444432 |
| RUNX1 | runt-related transcription factor 1 | 0.0429404 |
| SEPTIN9 | septin 9 | 0.0376654 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0376254 |
| AHNAK | AHNAK nucleoprotein | 0.037615 |
| ATP13A3 | ATPase type 13A3 | 0.0370801 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0357967 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0341936 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0338122 |
| DST | dystonin | 0.0336317 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0332399 |
| SBF2 | SET binding factor 2 | 0.0327814 |
| VEGFA | vascular endothelial growth factor A | 0.0319994 |
| PLAT | plasminogen activator, tissue | 0.0319676 |
| GPC6 | glypican 6 | 0.0318528 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0289572 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0285468 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0284837 |
| NDRG1 | N-myc downstream regulated 1 | 0.0282495 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0279114 |
| NAV2 | neuron navigator 2 | 0.0278353 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0276909 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0276217 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0270985 |
| TPM3 | tropomyosin 3 | 0.0260397 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0251703 |
| RTN4 | reticulon 4 | 0.0246664 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0242994 |
| FLNA | filamin A, alpha | 0.0241553 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.02387 |
| ARRDC3 | arrestin domain containing 3 | 0.0236656 |
| AUTS2 | autism susceptibility candidate 2 | 0.023662 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.023332 |
| FNIP1 | folliculin interacting protein 1 | 0.0229695 |
| HLA-A | major histocompatibility complex, class I, A | 0.0227917 |
| ADAR | adenosine deaminase, RNA-specific | 0.022778 |
| THBS2 | thrombospondin 2 | 0.0226536 |
| CD109 | CD109 molecule | 0.022356 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0222431 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0220472 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0219861 |
| OGA | O-GlcNAcase | 0.0219283 |
| SETD5 | SET domain containing 5 | 0.0214299 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0212522 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.021182 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0211109 |
| COL5A2 | collagen, type V, alpha 2 | 0.021039 |
| ZNF292 | zinc finger protein 292 | 0.0209289 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0206616 |
| MYOF | myoferlin | 0.0203662 |
| C1D | C1D nuclear receptor corepressor | 0.0203541 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0202181 |
| CLU | clusterin | 0.0201288 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0200708 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0199533 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0195251 |
| COL1A2 | collagen, type I, alpha 2 | 0.0193269 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0191274 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0191102 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0189465 |
| ANXA2 | annexin A2 | 0.0189141 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188106 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0188053 |
| SP3 | Sp3 transcription factor | 0.0188028 |
| MSN | moesin | 0.0184157 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0183662 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0178822 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0177925 |
| HELZ | helicase with zinc finger | 0.0176696 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0175418 |
| RAI14 | retinoic acid induced 14 | 0.0172866 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0168641 |
| FRMD5 | FERM domain containing 5 | 0.0168174 |
| COL3A1 | collagen, type III, alpha 1 | 0.0167622 |
| MB21D2 | Mab-21 domain containing 2 | 0.0167411 |
| APP | amyloid beta (A4) precursor protein | 0.0166688 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0164772 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0163465 |
| PRELID2 | PRELI domain containing 2 | 0.0162891 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0159322 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0159233 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0158373 |
| NBAS | neuroblastoma amplified sequence | 0.0157344 |
| AFDN | afadin, adherens junction formation factor | 0.0156831 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0156285 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.171764 |
| VIM | vimentin | -0.132125 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129167 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0816683 |
| S100A10 | S100 calcium binding protein A10 | -0.0551457 |
| LMNA | lamin A/C | -0.0437933 |
| CSTB | cystatin B (stefin B) | -0.0370618 |
| S100A6 | S100 calcium binding protein A6 | -0.0328113 |
| PTMA | prothymosin, alpha | -0.0320757 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0287493 |
| FTL | ferritin, light polypeptide | -0.028681 |
| LDHA | lactate dehydrogenase A | -0.0242928 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.023277 |
| RIGI | RNA sensor RIG-I | -0.0230264 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0203115 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0201003 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0192442 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0187568 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0185309 |
| CDH13 | cadherin 13 | -0.0183874 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0182266 |
| CAVIN1 | caveolae associated protein 1 | -0.0179144 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0176456 |
| TPM4 | tropomyosin 4 | -0.0174719 |
| RPLP1 | ribosomal protein, large, P1 | -0.0171783 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0166843 |
| CCND1 | cyclin D1 | -0.0160714 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0153533 |
| RPS24 | ribosomal protein S24 | -0.0152081 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0150467 |
| PKM | pyruvate kinase, muscle | -0.014157 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0138156 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0133747 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0132505 |
| SEC61G | Sec61 gamma subunit | -0.0131487 |
| S100A4 | S100 calcium binding protein A4 | -0.0126584 |
| FN1 | fibronectin 1 | -0.0126491 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0121094 |
| RPL34 | ribosomal protein L34 | -0.0119533 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0117639 |
| RPL23 | ribosomal protein L23 | -0.0117409 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0115871 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0115036 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0114339 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0112379 |
| RPL35A | ribosomal protein L35a | -0.0111571 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0110047 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0109449 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0108146 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0107743 |
| RRBP1 | ribosome binding protein 1 | -0.0107229 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0106887 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0105199 |
| ARF1 | ADP-ribosylation factor 1 | -0.0103595 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0102929 |
| SP100 | SP100 nuclear antigen | -0.0102368 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00997014 |
| RPS5 | ribosomal protein S5 | -0.0098783 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00987768 |
| TAOK1 | TAO kinase 1 | -0.00981962 |
| RPS19 | ribosomal protein S19 | -0.00963701 |
| TAGLN2 | transgelin 2 | -0.00949865 |
| GNAS | GNAS complex locus | -0.0094854 |
| RPL32 | ribosomal protein L32 | -0.00939123 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00935136 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.00934822 |
| H3-3B | H3.3 histone B | -0.00933292 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.00932066 |
| CEP350 | centrosomal protein 350kDa | -0.00930204 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00925431 |
| HDLBP | high density lipoprotein binding protein | -0.00923026 |
| TUBB | tubulin, beta class I | -0.00922863 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00910853 |
| ASTN2 | astrotactin 2 | -0.00899967 |
| S100A11 | S100 calcium binding protein A11 | -0.00898631 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00897988 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00893807 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.00876851 |
| RPL31 | ribosomal protein L31 | -0.00872771 |
| RPL12 | ribosomal protein L12 | -0.0086892 |
| TBCA | tubulin folding cofactor A | -0.00864442 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00859274 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0085376 |
| KRT81 | keratin 81, type II | -0.00845175 |
| LRRC17 | leucine rich repeat containing 17 | -0.00827756 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.00822938 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00822219 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0081106 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00810996 |
| CYTH3 | cytohesin 3 | -0.00805724 |
| CTSD | cathepsin D | -0.00805401 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00787533 |
| RPL19 | ribosomal protein L19 | -0.0078338 |
| NPR2 | natriuretic peptide receptor 2 | -0.00758354 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.00758077 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00757618 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.00756615 |
| PRSS23 | protease, serine, 23 | -0.0075358 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.00747084 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.00746796 |
