| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.104669 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102579 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0778085 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0562083 |
| TMSB4X | thymosin beta 4, X-linked | 0.0505635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498718 |
| PCBP2 | poly(rC) binding protein 2 | 0.0477485 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0470031 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0445948 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0396568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0376948 |
| FN1 | fibronectin 1 | 0.0366612 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337124 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0335377 |
| ITGAV | integrin, alpha V | 0.033426 |
| QKI | QKI, KH domain containing, RNA binding | 0.0327758 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0325572 |
| YBX1 | Y box binding protein 1 | 0.0307313 |
| TOP1 | topoisomerase (DNA) I | 0.0306779 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293756 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0290053 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0285894 |
| CCNL1 | cyclin L1 | 0.0284853 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0282996 |
| CALR | calreticulin | 0.0282358 |
| HELZ | helicase with zinc finger | 0.0280155 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0278355 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0276498 |
| ENO1 | enolase 1, (alpha) | 0.0271655 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0269504 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0267357 |
| FMNL2 | formin-like 2 | 0.0264688 |
| ASPH | aspartate beta-hydroxylase | 0.0264023 |
| EFNA5 | ephrin-A5 | 0.0261989 |
| DST | dystonin | 0.0260903 |
| ZNF608 | zinc finger protein 608 | 0.0259938 |
| VEGFA | vascular endothelial growth factor A | 0.0257864 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0255113 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0246912 |
| RPL36 | ribosomal protein L36 | 0.0246107 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0246087 |
| ZNF292 | zinc finger protein 292 | 0.0244045 |
| PRELID2 | PRELI domain containing 2 | 0.0242014 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240431 |
| ZNF148 | zinc finger protein 148 | 0.02391 |
| AHNAK | AHNAK nucleoprotein | 0.0239096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0238726 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0235266 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0231903 |
| ADAR | adenosine deaminase, RNA-specific | 0.0231386 |
| B2M | beta-2-microglobulin | 0.0229138 |
| RPL23 | ribosomal protein L23 | 0.0227788 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0227091 |
| NDRG1 | N-myc downstream regulated 1 | 0.022642 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0225886 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0225647 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0222659 |
| TPM3 | tropomyosin 3 | 0.0221161 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0220453 |
| GPHN | gephyrin | 0.0220356 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0218916 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0216102 |
| NFYA | nuclear transcription factor Y, alpha | 0.021597 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0215466 |
| UBC | ubiquitin C | 0.0213804 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0213355 |
| H1-0 | H1.0 linker histone | 0.0212364 |
| SETD5 | SET domain containing 5 | 0.0212187 |
| HELLS | helicase, lymphoid-specific | 0.0212184 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0211232 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0209748 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0206306 |
| EXOC4 | exocyst complex component 4 | 0.0205082 |
| SPAG9 | sperm associated antigen 9 | 0.0205005 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.020449 |
| PDGFC | platelet derived growth factor C | 0.0202793 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0201397 |
| RTN4 | reticulon 4 | 0.0200043 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0197548 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.01963 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0195666 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0195466 |
| NBAS | neuroblastoma amplified sequence | 0.0194116 |
| SRP54 | signal recognition particle 54kDa | 0.0193385 |
| BBX | bobby sox homolog (Drosophila) | 0.0192315 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0191709 |
| APP | amyloid beta (A4) precursor protein | 0.0191033 |
| MKI67 | marker of proliferation Ki-67 | 0.0190995 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0190821 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0187809 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0187707 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0187216 |
| RBM39 | RNA binding motif protein 39 | 0.0187145 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0186508 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0184414 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0184228 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0184216 |
| BRD4 | bromodomain containing 4 | 0.0183891 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0183754 |
| RPL12 | ribosomal protein L12 | 0.0183485 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.145917 |
| PEG10 | paternally expressed 10 | -0.0985454 |
| CADM2 | cell adhesion molecule 2 | -0.0614836 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.060245 |
| HMGA2 | high mobility group AT-hook 2 | -0.0561162 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0462543 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0402403 |
| IER3 | immediate early response 3 | -0.0399578 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0398133 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0328988 |
| VCL | vinculin | -0.0302486 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0301438 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0298871 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294645 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0280031 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0275614 |
| FNIP1 | folliculin interacting protein 1 | -0.0273111 |
| MGP | matrix Gla protein | -0.0260754 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0257455 |
| ACTG1 | actin gamma 1 | -0.0252578 |
| HMGA1 | high mobility group AT-hook 1 | -0.0247309 |
| CTBP2 | C-terminal binding protein 2 | -0.0245743 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.023525 |
| RPS24 | ribosomal protein S24 | -0.0219714 |
| RPS20 | ribosomal protein S20 | -0.0217622 |
| PCM1 | pericentriolar material 1 | -0.0214937 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0211282 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0211268 |
| LDHA | lactate dehydrogenase A | -0.0207262 |
| RREB1 | ras responsive element binding protein 1 | -0.0201893 |
| FOXC1 | forkhead box C1 | -0.0201459 |
| RAI1 | retinoic acid induced 1 | -0.0197686 |
| TRIM9 | tripartite motif containing 9 | -0.0197586 |
| ATXN2 | ataxin 2 | -0.0195988 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0183915 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0176779 |
| CLTC | clathrin, heavy chain (Hc) | -0.017615 |
| PRLR | prolactin receptor | -0.0173653 |
| CREM | cAMP responsive element modulator | -0.0172284 |
| ZFHX3 | zinc finger homeobox 3 | -0.0170413 |
| TPM4 | tropomyosin 4 | -0.0169905 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | -0.0167351 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.016603 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | -0.0165591 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0164728 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0161919 |
| ZNF160 | zinc finger protein 160 | -0.0161755 |
| BCOR | BCL6 corepressor | -0.0161033 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0160835 |
| PHIP | pleckstrin homology domain interacting protein | -0.0160489 |
| ZNF638 | zinc finger protein 638 | -0.0156294 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0155191 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0155069 |
| WASHC5 | WASH complex subunit 5 | -0.0153514 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.015259 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0151434 |
| KAZN | kazrin, periplakin interacting protein | -0.0148533 |
| ATF6 | activating transcription factor 6 | -0.0147833 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0147744 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0147437 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0147205 |
| RSU1 | Ras suppressor protein 1 | -0.0147111 |
| SETX | senataxin | -0.0146844 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0146785 |
| KIAA0232 | KIAA0232 | -0.014534 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.014418 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0143542 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0143531 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0140394 |
| ARHGAP19 | Rho GTPase activating protein 19 | -0.0139491 |
| GOLGA8A | golgin A8 family, member A | -0.0137337 |
| KIF1A | kinesin family member 1A | -0.0136267 |
| XPO1 | exportin 1 | -0.013504 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0134438 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0134404 |
| ACTN1 | actinin, alpha 1 | -0.013421 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0133301 |
| ATP11A | ATPase, class VI, type 11A | -0.0131977 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | -0.013183 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0131545 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.012929 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0127713 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0127674 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0127514 |
| DIAPH3 | diaphanous-related formin 3 | -0.0126003 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.012532 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0124638 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0124584 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0124062 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0124007 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | -0.0123129 |
| SIK3 | SIK family kinase 3 | -0.0122009 |
| MRTFA | myocardin related transcription factor A | -0.0121847 |
| ZNF407 | zinc finger protein 407 | -0.012084 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0120771 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.012061 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0120089 |
| ZNF43 | zinc finger protein 43 | -0.0119764 |
| PARD3 | par-3 family cell polarity regulator | -0.0119487 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0116269 |
