| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.177803 |
| NDRG1 | N-myc downstream regulated 1 | 0.0903521 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0635448 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0566666 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0562727 |
| NUP58 | nucleoporin 58 | 0.0506006 |
| CD109 | CD109 molecule | 0.050581 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0495323 |
| CDC73 | cell division cycle 73 | 0.0457873 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0451042 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0446257 |
| GPC6 | glypican 6 | 0.0445866 |
| NAV2 | neuron navigator 2 | 0.0438174 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0433088 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0389008 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0357262 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0340936 |
| ZNF292 | zinc finger protein 292 | 0.0328012 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0326994 |
| A2M | alpha-2-macroglobulin | 0.0314462 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0313521 |
| COPA | coatomer protein complex, subunit alpha | 0.0302634 |
| NBAS | neuroblastoma amplified sequence | 0.0302132 |
| MT2A | metallothionein 2A | 0.0298423 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0296783 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0291086 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0290536 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0286734 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0283065 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0277941 |
| CCNL1 | cyclin L1 | 0.0269661 |
| MRTFA | myocardin related transcription factor A | 0.0265199 |
| TMEM178B | transmembrane protein 178B | 0.0260573 |
| RBM33 | RNA binding motif protein 33 | 0.024849 |
| HELZ | helicase with zinc finger | 0.0247527 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0243954 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0243017 |
| AFDN | afadin, adherens junction formation factor | 0.0242727 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0236345 |
| RLF | rearranged L-myc fusion | 0.0233629 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0229182 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0228274 |
| SRPK2 | SRSF protein kinase 2 | 0.0217503 |
| TPD52 | tumor protein D52 | 0.0217032 |
| ANXA2 | annexin A2 | 0.0211227 |
| APP | amyloid beta (A4) precursor protein | 0.0210762 |
| ATP13A3 | ATPase type 13A3 | 0.021013 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.020778 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0207436 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0205954 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0205541 |
| TPR | translocated promoter region, nuclear basket protein | 0.0198581 |
| FOSL1 | FOS-like antigen 1 | 0.0196603 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.019265 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191918 |
| TNPO3 | transportin 3 | 0.0189974 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0187958 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0187643 |
| TFRC | transferrin receptor | 0.0187344 |
| SBF2 | SET binding factor 2 | 0.0186022 |
| BRD2 | bromodomain containing 2 | 0.018483 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0183583 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0182852 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0181882 |
| FLNB | filamin B, beta | 0.0181824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0179958 |
| SMAD3 | SMAD family member 3 | 0.0179864 |
| BBX | bobby sox homolog (Drosophila) | 0.0179567 |
| ZNF638 | zinc finger protein 638 | 0.0177348 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0176992 |
| WDR45B | WD repeat domain 45B | 0.0176809 |
| ZNF654 | zinc finger protein 654 | 0.017414 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0173186 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0173182 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0171329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0170817 |
| FBXO7 | F-box protein 7 | 0.016979 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0169202 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0168136 |
| ADM | adrenomedullin | 0.0165902 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0163538 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0161289 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0159537 |
| PLK2 | polo-like kinase 2 | 0.0159437 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.015845 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0157258 |
| PCBP2 | poly(rC) binding protein 2 | 0.0156452 |
| TNNC1 | troponin C type 1 (slow) | 0.0156337 |
| RGS2 | regulator of G-protein signaling 2 | 0.0155244 |
| SPAG9 | sperm associated antigen 9 | 0.0154266 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0153961 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0153833 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0151648 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0150738 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0150557 |
| XPO1 | exportin 1 | 0.0149497 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.014925 |
| NEK7 | NIMA-related kinase 7 | 0.0149049 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0149042 |
| NUMB | numb homolog (Drosophila) | 0.0148741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.155785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0980826 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0894233 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.083016 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0671251 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644842 |
| NLGN1 | neuroligin 1 | -0.0621416 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.061643 |
| S100A6 | S100 calcium binding protein A6 | -0.0578117 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.054381 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0528254 |
| TMSB10 | thymosin beta 10 | -0.0528068 |
| HLA-B | major histocompatibility complex, class I, B | -0.0438264 |
| VGF | VGF nerve growth factor inducible | -0.0427041 |
| PTMA | prothymosin, alpha | -0.0423268 |
| DCT | dopachrome tautomerase | -0.0417062 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0349804 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0316571 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0313471 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305939 |
| S100A9 | S100 calcium binding protein A9 | -0.0300672 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0295613 |
| FRMD4A | FERM domain containing 4A | -0.0283712 |
| IER3 | immediate early response 3 | -0.0259748 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.025261 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0244919 |
| ACTG1 | actin gamma 1 | -0.0241449 |
| FTL | ferritin, light polypeptide | -0.0236081 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0231085 |
| RPS8 | ribosomal protein S8 | -0.0226654 |
| PCDH7 | protocadherin 7 | -0.0222926 |
| RPL37A | ribosomal protein L37a | -0.0220075 |
| OXR1 | oxidation resistance 1 | -0.0214388 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0209054 |
| CTTNBP2 | cortactin binding protein 2 | -0.019868 |
| RPL35A | ribosomal protein L35a | -0.0197446 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0195979 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0194178 |
| HLA-A | major histocompatibility complex, class I, A | -0.019361 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0191565 |
| CD63 | CD63 molecule | -0.019066 |
| MTDH | metadherin | -0.0178082 |
| RHOA | ras homolog family member A | -0.0177525 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.017695 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.017663 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0175688 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0175272 |
| PLIN2 | perilipin 2 | -0.0168726 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0166157 |
| RPLP2 | ribosomal protein, large, P2 | -0.0165676 |
| SDC2 | syndecan 2 | -0.0165464 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0163161 |
| RPL34 | ribosomal protein L34 | -0.0160064 |
| RRBP1 | ribosome binding protein 1 | -0.0156525 |
| MACROD2 | MACRO domain containing 2 | -0.0152103 |
| S100A10 | S100 calcium binding protein A10 | -0.0151763 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0151613 |
| RPS24 | ribosomal protein S24 | -0.0150803 |
| SCFD2 | sec1 family domain containing 2 | -0.0149122 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0147745 |
| CTSD | cathepsin D | -0.0143924 |
| EHBP1 | EH domain binding protein 1 | -0.0143187 |
| RPS12 | ribosomal protein S12 | -0.014034 |
| ZNF704 | zinc finger protein 704 | -0.0137626 |
| RPL26 | ribosomal protein L26 | -0.0135909 |
| FAM162A | family with sequence similarity 162, member A | -0.0135545 |
| TAGLN2 | transgelin 2 | -0.0133718 |
| PERP | PERP, TP53 apoptosis effector | -0.0131467 |
| MAP1B | microtubule-associated protein 1B | -0.0131291 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0130862 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0128921 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.012852 |
| RPL23 | ribosomal protein L23 | -0.0127997 |
| RPS29 | ribosomal protein S29 | -0.0126343 |
| RPL30 | ribosomal protein L30 | -0.0125666 |
| GNAS | GNAS complex locus | -0.0123956 |
| CCND1 | cyclin D1 | -0.0123578 |
| ITGB8 | integrin, beta 8 | -0.0123414 |
| RPS15 | ribosomal protein S15 | -0.0119087 |
| LDHA | lactate dehydrogenase A | -0.0117597 |
| GDF15 | growth differentiation factor 15 | -0.0116894 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0116133 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0115603 |
| HMGB1 | high mobility group box 1 | -0.0114 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0113733 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0113291 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0113175 |
| RPL12 | ribosomal protein L12 | -0.0112574 |
| GHR | growth hormone receptor | -0.0112328 |
| RPL9 | ribosomal protein L9 | -0.0111521 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0110998 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0108851 |
| RPL8 | ribosomal protein L8 | -0.0108779 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0108304 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.010784 |
| RPS3 | ribosomal protein S3 | -0.0107185 |
| CANX | calnexin | -0.0107054 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0106314 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0105585 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0105356 |
