| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.105189 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.099964 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0945075 |
| TMSB4X | thymosin beta 4, X-linked | 0.0895889 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0858552 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0803514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0686857 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0618147 |
| AHNAK | AHNAK nucleoprotein | 0.0557581 |
| ANXA2 | annexin A2 | 0.0547397 |
| MT2A | metallothionein 2A | 0.0542119 |
| MT1X | metallothionein 1X | 0.0540946 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0522963 |
| SPAG9 | sperm associated antigen 9 | 0.0514365 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0509702 |
| RBM39 | RNA binding motif protein 39 | 0.0502691 |
| OGA | O-GlcNAcase | 0.0470388 |
| FAM13A | family with sequence similarity 13, member A | 0.046046 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0433696 |
| SMAD3 | SMAD family member 3 | 0.0433463 |
| APP | amyloid beta (A4) precursor protein | 0.0429127 |
| UBC | ubiquitin C | 0.0426172 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0424873 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0396825 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0396131 |
| CD2AP | CD2-associated protein | 0.0388485 |
| TOP1 | topoisomerase (DNA) I | 0.0386929 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0386219 |
| CCNL1 | cyclin L1 | 0.0386112 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0384283 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0381811 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0378336 |
| HLA-A | major histocompatibility complex, class I, A | 0.0376369 |
| KLF6 | Kruppel-like factor 6 | 0.0374793 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0372521 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0372138 |
| RTN4 | reticulon 4 | 0.035206 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0342578 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0339678 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0334498 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0329455 |
| ARRDC3 | arrestin domain containing 3 | 0.0328968 |
| CANX | calnexin | 0.0326672 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0326382 |
| NDRG1 | N-myc downstream regulated 1 | 0.0323494 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0318659 |
| HLA-C | major histocompatibility complex, class I, C | 0.0318614 |
| HPCAL1 | hippocalcin-like 1 | 0.0312922 |
| MYOF | myoferlin | 0.0309828 |
| HELZ | helicase with zinc finger | 0.0308125 |
| ABI1 | abl-interactor 1 | 0.0305658 |
| PLAU | plasminogen activator, urokinase | 0.0304695 |
| PTMA | prothymosin, alpha | 0.0303921 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0296374 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0288093 |
| ZNF292 | zinc finger protein 292 | 0.0285088 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0281782 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0281529 |
| NUP58 | nucleoporin 58 | 0.0281297 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0278905 |
| YTHDC1 | YTH domain containing 1 | 0.0271936 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0269909 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0269196 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0263412 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.026139 |
| CCNY | cyclin Y | 0.0260841 |
| CDC73 | cell division cycle 73 | 0.0258384 |
| RLF | rearranged L-myc fusion | 0.0257561 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0253666 |
| EREG | epiregulin | 0.0252891 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0251587 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0250133 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0247715 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0246026 |
| USP3 | ubiquitin specific peptidase 3 | 0.024573 |
| YBX1 | Y box binding protein 1 | 0.0245115 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0242181 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0238218 |
| ANXA1 | annexin A1 | 0.023807 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.023289 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0232756 |
| NEK7 | NIMA-related kinase 7 | 0.0231629 |
| TFG | TRK-fused gene | 0.0231024 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0230104 |
| NPTN | neuroplastin | 0.0228699 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0228439 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0227546 |
| ACTG1 | actin gamma 1 | 0.0227004 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0226878 |
| HLA-E | major histocompatibility complex, class I, E | 0.022625 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0225136 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0224512 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0221984 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.022127 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0219681 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0219493 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0219245 |
| ANKRD11 | ankyrin repeat domain 11 | 0.021908 |
| SUCO | SUN domain containing ossification factor | 0.0218902 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0217113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.122823 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0655344 |
| TMSB10 | thymosin beta 10 | -0.05673 |
| CP | ceruloplasmin (ferroxidase) | -0.0489325 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0480033 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0428007 |
| KRT19 | keratin 19, type I | -0.039606 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.035027 |
| PKM | pyruvate kinase, muscle | -0.0345548 |
| LAMA4 | laminin, alpha 4 | -0.033719 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0326521 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0325073 |
| EGR1 | early growth response 1 | -0.0314972 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0309654 |
| LAMC2 | laminin, gamma 2 | -0.0296267 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0279512 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0266832 |
| APOL1 | apolipoprotein L, 1 | -0.0264306 |
| MMP7 | matrix metallopeptidase 7 | -0.0264 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0254367 |
| LCN2 | lipocalin 2 | -0.0243959 |
| HLA-B | major histocompatibility complex, class I, B | -0.0237502 |
| B2M | beta-2-microglobulin | -0.0236243 |
| ITGA6 | integrin, alpha 6 | -0.0231482 |
| RAD51B | RAD51 paralog B | -0.0228887 |
| NCKAP5 | NCK-associated protein 5 | -0.0226831 |
| PCDH7 | protocadherin 7 | -0.0220517 |
| POTEF | POTE ankyrin domain family, member F | -0.021749 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0212679 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0212649 |
| HMGA2 | high mobility group AT-hook 2 | -0.0209262 |
| EGFR | epidermal growth factor receptor | -0.0208353 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0204967 |
| TPM4 | tropomyosin 4 | -0.0200915 |
| HMGA1 | high mobility group AT-hook 1 | -0.0200222 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0197656 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0197 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0196259 |
| RASAL2 | RAS protein activator like 2 | -0.0196251 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0195933 |
| EFNA5 | ephrin-A5 | -0.0195342 |
| CDK6 | cyclin-dependent kinase 6 | -0.0192156 |
| MX2 | MX dynamin-like GTPase 2 | -0.0191837 |
| S100A11 | S100 calcium binding protein A11 | -0.0191821 |
| RPS29 | ribosomal protein S29 | -0.0185079 |
| DTNA | dystrobrevin, alpha | -0.0184649 |
| S100A6 | S100 calcium binding protein A6 | -0.0184368 |
| KYNU | kynureninase | -0.0183247 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0175746 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0172687 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0172085 |
| PRKCA | protein kinase C, alpha | -0.0170696 |
| PLAT | plasminogen activator, tissue | -0.0169814 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.016891 |
| TAPBP | TAP binding protein (tapasin) | -0.0167515 |
| RCOR1 | REST corepressor 1 | -0.015916 |
| RPS19 | ribosomal protein S19 | -0.0157477 |
| S100A10 | S100 calcium binding protein A10 | -0.0153682 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0152505 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0151013 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0146452 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0145539 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0145425 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.014068 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0140324 |
| HDAC9 | histone deacetylase 9 | -0.0139453 |
| TMC5 | transmembrane channel-like 5 | -0.0137715 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0135392 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0132129 |
| NRG3 | neuregulin 3 | -0.0131957 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.013188 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.013157 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0131405 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0131345 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0130451 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0130112 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0129718 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0129614 |
| S100P | S100 calcium binding protein P | -0.0126903 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0126874 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.012665 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0125735 |
| ATXN1 | ataxin 1 | -0.0124459 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0123897 |
| GOLGB1 | golgin B1 | -0.0123742 |
| CMIP | c-Maf inducing protein | -0.0121818 |
| RANBP17 | RAN binding protein 17 | -0.0121142 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0116092 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0116023 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0115382 |
| ANXA4 | annexin A4 | -0.0113998 |
| GLIS3 | GLIS family zinc finger 3 | -0.0112987 |
| ITGB4 | integrin, beta 4 | -0.0112318 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0111505 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0110248 |
| DST | dystonin | -0.0110183 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0109988 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0109251 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0109117 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0107259 |
