| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.182075 |
| FAM13A | family with sequence similarity 13, member A | 0.0775215 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0681314 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0604685 |
| HELZ | helicase with zinc finger | 0.0603963 |
| VEGFA | vascular endothelial growth factor A | 0.046352 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0438508 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0396024 |
| SEPTIN9 | septin 9 | 0.0391464 |
| NDRG1 | N-myc downstream regulated 1 | 0.036277 |
| RPL37A | ribosomal protein L37a | 0.0350971 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0336124 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333694 |
| RPS6 | ribosomal protein S6 | 0.0332096 |
| RPL35A | ribosomal protein L35a | 0.0318178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0317352 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0314141 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0310856 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0295797 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0287457 |
| ACTG1 | actin gamma 1 | 0.02857 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0283087 |
| GOLGA4 | golgin A4 | 0.0283058 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0273533 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0270582 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.026988 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0265751 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0264046 |
| RPS2 | ribosomal protein S2 | 0.0260092 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0258213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0251574 |
| RPS8 | ribosomal protein S8 | 0.0245853 |
| MEF2A | myocyte enhancer factor 2A | 0.0241726 |
| RPS12 | ribosomal protein S12 | 0.0241607 |
| ANXA2 | annexin A2 | 0.0241473 |
| FNBP1 | formin binding protein 1 | 0.0239574 |
| RPL34 | ribosomal protein L34 | 0.0233749 |
| PTMA | prothymosin, alpha | 0.0227388 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0223324 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0222799 |
| PKM | pyruvate kinase, muscle | 0.0218221 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0213012 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0212591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0210453 |
| RPL27 | ribosomal protein L27 | 0.0205906 |
| QKI | QKI, KH domain containing, RNA binding | 0.0200956 |
| RPS19 | ribosomal protein S19 | 0.0200506 |
| PHIP | pleckstrin homology domain interacting protein | 0.0199355 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0198258 |
| DTNA | dystrobrevin, alpha | 0.0197474 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0195349 |
| TRIB2 | tribbles pseudokinase 2 | 0.0190487 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0188155 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0187122 |
| SQSTM1 | sequestosome 1 | 0.0185932 |
| PFN1 | profilin 1 | 0.0184594 |
| RPL7 | ribosomal protein L7 | 0.0183352 |
| RPL38 | ribosomal protein L38 | 0.0176788 |
| RPS3 | ribosomal protein S3 | 0.017337 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0173124 |
| RPL26 | ribosomal protein L26 | 0.0172801 |
| RPL28 | ribosomal protein L28 | 0.0172601 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0172425 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0172132 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0169792 |
| RPL19 | ribosomal protein L19 | 0.0168133 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0167102 |
| ANGPTL4 | angiopoietin-like 4 | 0.0165653 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0164918 |
| LMNA | lamin A/C | 0.0163438 |
| RARA | retinoic acid receptor, alpha | 0.0162714 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0162487 |
| POTEF | POTE ankyrin domain family, member F | 0.0162417 |
| CASC3 | cancer susceptibility candidate 3 | 0.0162216 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0161133 |
| RLF | rearranged L-myc fusion | 0.0160298 |
| OGA | O-GlcNAcase | 0.0159678 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0157831 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0157326 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0156465 |
| RYBP | RING1 and YY1 binding protein | 0.0156115 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0154745 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0154153 |
| PDS5B | PDS5 cohesin associated factor B | 0.0152612 |
| CCNL1 | cyclin L1 | 0.0150114 |
| RPS14 | ribosomal protein S14 | 0.0150017 |
| RPL36 | ribosomal protein L36 | 0.0149969 |
| WDR45B | WD repeat domain 45B | 0.014925 |
| NUP58 | nucleoporin 58 | 0.0146864 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0146356 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.014631 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.0146186 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0146025 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0145589 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0144924 |
| CXXC5 | CXXC finger protein 5 | 0.0144216 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0143182 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0142656 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0142488 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0142213 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.15016 |
| LSAMP | limbic system-associated membrane protein | -0.108979 |
| SYT1 | synaptotagmin I | -0.0676242 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0625258 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0619216 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0606454 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0593937 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0527172 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0504447 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0500616 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0457074 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0451557 |
| NREP | neuronal regeneration related protein | -0.0439403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0438587 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0421782 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0420904 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.040442 |
| FMN1 | formin 1 | -0.0398569 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0386969 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0382186 |
| FRMD4A | FERM domain containing 4A | -0.0372931 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0369146 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0365594 |
| KLHL13 | kelch-like family member 13 | -0.0362973 |
| COL3A1 | collagen, type III, alpha 1 | -0.0352226 |
| PLAT | plasminogen activator, tissue | -0.0347937 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.03448 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0339656 |
| RNF213 | ring finger protein 213 | -0.0339544 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0338142 |
| BPTF | bromodomain PHD finger transcription factor | -0.0336589 |
| ZNF804A | zinc finger protein 804A | -0.0334118 |
| PRKCA | protein kinase C, alpha | -0.0333253 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0332008 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0318971 |
| CADM2 | cell adhesion molecule 2 | -0.0314881 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0300982 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.029956 |
| AOPEP | aminopeptidase O (putative) | -0.0290786 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0284685 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0283276 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0282941 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0282497 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0277691 |
| ATRNL1 | attractin-like 1 | -0.0269871 |
| AUTS2 | autism susceptibility candidate 2 | -0.0264285 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.026373 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0263115 |
| PCDH9 | protocadherin 9 | -0.0256703 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0256666 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0237352 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0219372 |
| VCL | vinculin | -0.0217931 |
| GPC5 | glypican 5 | -0.0217128 |
| PHF14 | PHD finger protein 14 | -0.0215618 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0213582 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0212249 |
| ITGA1 | integrin, alpha 1 | -0.0211452 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0210762 |
| COL4A6 | collagen, type IV, alpha 6 | -0.020996 |
| CUX1 | cut-like homeobox 1 | -0.0206772 |
| NRP1 | neuropilin 1 | -0.0206332 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0204213 |
| CEP350 | centrosomal protein 350kDa | -0.0204153 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.020378 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0203739 |
| NBEA | neurobeachin | -0.0203492 |
| AEBP2 | AE binding protein 2 | -0.0202447 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0201626 |
| VMP1 | vacuole membrane protein 1 | -0.0201352 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0200447 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0199818 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0197348 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0196698 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0195315 |
| DNM3 | dynamin 3 | -0.0194153 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0194101 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0192555 |
| PLPP1 | phospholipid phosphatase 1 | -0.0188965 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0188935 |
| GLI3 | GLI family zinc finger 3 | -0.0184638 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0183231 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0182168 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0181296 |
| PHF3 | PHD finger protein 3 | -0.0180792 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0179566 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.017914 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0179015 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0179005 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.01775 |
| SIK2 | salt-inducible kinase 2 | -0.0176758 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.017297 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.01709 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0167687 |
| VIM | vimentin | -0.0167608 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0166437 |
| TPM1 | tropomyosin 1 (alpha) | -0.0165135 |
| EXOC4 | exocyst complex component 4 | -0.0164499 |
| FOXP1 | forkhead box P1 | -0.0161877 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0159588 |
