| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Rucaparib (phosphate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.110772 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.10322 |
| NDRG1 | N-myc downstream regulated 1 | 0.0510241 |
| FAM13A | family with sequence similarity 13, member A | 0.0502355 |
| FN1 | fibronectin 1 | 0.047578 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0427493 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0425341 |
| RPS8 | ribosomal protein S8 | 0.0365413 |
| VEGFA | vascular endothelial growth factor A | 0.0357237 |
| AHNAK | AHNAK nucleoprotein | 0.0352881 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0326814 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0323157 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0321454 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0318805 |
| SBF2 | SET binding factor 2 | 0.0308877 |
| RPL28 | ribosomal protein L28 | 0.0302198 |
| RPL35A | ribosomal protein L35a | 0.029831 |
| EGFR | epidermal growth factor receptor | 0.0292067 |
| HLA-A | major histocompatibility complex, class I, A | 0.0289101 |
| COL5A1 | collagen, type V, alpha 1 | 0.0286474 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0284832 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0276067 |
| DST | dystonin | 0.0266569 |
| ANXA2 | annexin A2 | 0.0257378 |
| CANX | calnexin | 0.0251304 |
| CADM1 | cell adhesion molecule 1 | 0.0246113 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0238625 |
| HLA-B | major histocompatibility complex, class I, B | 0.0234985 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0233583 |
| GDF15 | growth differentiation factor 15 | 0.0232538 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0229906 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0219422 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0209788 |
| FNIP1 | folliculin interacting protein 1 | 0.0209236 |
| CALR | calreticulin | 0.0207956 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0199524 |
| FLNA | filamin A, alpha | 0.0196309 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0195839 |
| HLA-C | major histocompatibility complex, class I, C | 0.0192869 |
| INHBA | inhibin, beta A | 0.0191265 |
| RPL13A | ribosomal protein L13a | 0.0190629 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0189383 |
| RUNX1 | runt-related transcription factor 1 | 0.0188687 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.018671 |
| NAV2 | neuron navigator 2 | 0.0183203 |
| TNS3 | tensin 3 | 0.0176689 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.017618 |
| STK17A | serine/threonine kinase 17a | 0.0171294 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0170923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0170694 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0170606 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0170216 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.016924 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.016902 |
| ANLN | anillin, actin binding protein | 0.0168755 |
| HDAC9 | histone deacetylase 9 | 0.0167498 |
| ZNF841 | zinc finger protein 841 | 0.0166161 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0164725 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0162581 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0156642 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0155558 |
| RPS3 | ribosomal protein S3 | 0.0155196 |
| PTCHD4 | patched domain containing 4 | 0.0154553 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0151643 |
| NAV1 | neuron navigator 1 | 0.0151581 |
| ATF4 | activating transcription factor 4 | 0.0150019 |
| SPAG9 | sperm associated antigen 9 | 0.0149626 |
| CDK13 | cyclin-dependent kinase 13 | 0.0146997 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0146294 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0144484 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0142812 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0141542 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0141376 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0140619 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0140028 |
| CTSB | cathepsin B | 0.0138798 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0138154 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0136454 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0136331 |
| CALD1 | caldesmon 1 | 0.0134417 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0134177 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0132893 |
| RACK1 | receptor for activated C kinase 1 | 0.0130633 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0128318 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0128306 |
| HM13 | histocompatibility (minor) 13 | 0.0127312 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0126869 |
| SQSTM1 | sequestosome 1 | 0.0125625 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0125121 |
| ZNF292 | zinc finger protein 292 | 0.0123921 |
| AK1 | adenylate kinase 1 | 0.0123033 |
| FAM219A | family with sequence similarity 219, member A | 0.0122727 |
| IGF2 | insulin-like growth factor 2 | 0.0122006 |
| ZNF395 | zinc finger protein 395 | 0.0121948 |
| FOXJ3 | forkhead box J3 | 0.0121046 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0120994 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0119126 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0117235 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0117152 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0117141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.15677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115647 |
| VIM | vimentin | -0.0944259 |
| TMSB10 | thymosin beta 10 | -0.0922054 |
| LDHA | lactate dehydrogenase A | -0.0413925 |
| PKM | pyruvate kinase, muscle | -0.0347223 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0299524 |
| EGR1 | early growth response 1 | -0.0259375 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0257207 |
| ASPH | aspartate beta-hydroxylase | -0.0253373 |
| UBC | ubiquitin C | -0.0253227 |
| TXNIP | thioredoxin interacting protein | -0.0241947 |
| RPLP1 | ribosomal protein, large, P1 | -0.0237389 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0225871 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0211795 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.020115 |
| VCL | vinculin | -0.0199882 |
| TPM4 | tropomyosin 4 | -0.0193014 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0181774 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0180847 |
| PTMA | prothymosin, alpha | -0.0176659 |
| TUBA1B | tubulin, alpha 1b | -0.016849 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0165777 |
| JUN | jun proto-oncogene | -0.0161262 |
| POTEF | POTE ankyrin domain family, member F | -0.0159689 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0156892 |
| VMP1 | vacuole membrane protein 1 | -0.0152706 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0151206 |
| RTN4 | reticulon 4 | -0.0146562 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.013566 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0135508 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0133599 |
| TXNRD1 | thioredoxin reductase 1 | -0.0124998 |
| TAGLN2 | transgelin 2 | -0.0123364 |
| S100A10 | S100 calcium binding protein A10 | -0.0120279 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0119259 |
| CBX3 | chromobox homolog 3 | -0.011885 |
| TAPBP | TAP binding protein (tapasin) | -0.0118087 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0117769 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0116174 |
| ETV1 | ets variant 1 | -0.0114961 |
| GLG1 | golgi glycoprotein 1 | -0.0113641 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0112829 |
| GLIS3 | GLIS family zinc finger 3 | -0.011087 |
| IL6ST | interleukin 6 signal transducer | -0.0109367 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0108603 |
| HMGA1 | high mobility group AT-hook 1 | -0.0107247 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0106277 |
| TNPO1 | transportin 1 | -0.010479 |
| MCL1 | myeloid cell leukemia 1 | -0.0104275 |
| RPL4 | ribosomal protein L4 | -0.0104033 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.010305 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.00972044 |
| CENPF | centromere protein F, 350/400kDa | -0.00971006 |
| GPX3 | glutathione peroxidase 3 | -0.0096491 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0093289 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00927941 |
| TUBB | tubulin, beta class I | -0.00922954 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00922225 |
| TOP1 | topoisomerase (DNA) I | -0.00917349 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00908778 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0089656 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00895471 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.00892884 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0089092 |
| WASF2 | WAS protein family, member 2 | -0.00890328 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.00887071 |
| RPL31 | ribosomal protein L31 | -0.00885379 |
| NRDC | nardilysin convertase | -0.00883218 |
| SERINC3 | serine incorporator 3 | -0.00874292 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0087092 |
| LOC112694756 | uncharaterized LOC112694756 | -0.00864873 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00860032 |
| RNF145 | ring finger protein 145 | -0.00855211 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.00850549 |
| DIAPH1 | diaphanous-related formin 1 | -0.00838887 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0083047 |
| PCBP2 | poly(rC) binding protein 2 | -0.00829714 |
| CLIC4 | chloride intracellular channel 4 | -0.0081481 |
| PALLD | palladin, cytoskeletal associated protein | -0.00808686 |
| MSN | moesin | -0.00808564 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.00806606 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00798481 |
| RNF11 | ring finger protein 11 | -0.00791109 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00785411 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00782835 |
| KYNU | kynureninase | -0.00780357 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00774889 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.00771227 |
| PERP | PERP, TP53 apoptosis effector | -0.00768799 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00767344 |
| GNAS | GNAS complex locus | -0.00762307 |
| CD44 | CD44 molecule (Indian blood group) | -0.00759062 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00757739 |
| NIBAN2 | niban apoptosis regulator 2 | -0.00757588 |
| IER2 | immediate early response 2 | -0.00756885 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.00752143 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00751135 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00746462 |
| CA9 | carbonic anhydrase IX | -0.00740655 |
