| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Rucaparib (phosphate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Rucaparib (phosphate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0871401 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0471685 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0362448 |
| AHNAK | AHNAK nucleoprotein | 0.0361061 |
| ANXA2 | annexin A2 | 0.0351102 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0314916 |
| VEGFA | vascular endothelial growth factor A | 0.0308056 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.030413 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0299454 |
| SQSTM1 | sequestosome 1 | 0.0290861 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0288882 |
| SMAD3 | SMAD family member 3 | 0.0280394 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0279641 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0276291 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0270939 |
| NDRG1 | N-myc downstream regulated 1 | 0.027068 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0267384 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.025506 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0251172 |
| KRT18 | keratin 18, type I | 0.0251001 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0246493 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.024488 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0244639 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0244018 |
| PTK2 | protein tyrosine kinase 2 | 0.0241163 |
| KRT8 | keratin 8, type II | 0.0239633 |
| FAT1 | FAT atypical cadherin 1 | 0.0227807 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0226521 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0217016 |
| TJP1 | tight junction protein 1 | 0.0211642 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0200957 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0198753 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0196486 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0191422 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0189171 |
| TMEM65 | transmembrane protein 65 | 0.018881 |
| ATXN1 | ataxin 1 | 0.0187738 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0185915 |
| CALU | calumenin | 0.018386 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0183756 |
| MYO1E | myosin IE | 0.0183491 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0178207 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0177981 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0173715 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0173115 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0168797 |
| PATJ | PATJ crumbs cell polarity complex component | 0.016794 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0167549 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0165068 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0163337 |
| BCL2L1 | BCL2-like 1 | 0.0162719 |
| ANXA11 | annexin A11 | 0.0159007 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0158652 |
| CTBP2 | C-terminal binding protein 2 | 0.015716 |
| FNIP1 | folliculin interacting protein 1 | 0.0157152 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0156649 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0156039 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0155215 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0154784 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0153414 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0152869 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0152635 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0151207 |
| GSK3B | glycogen synthase kinase 3 beta | 0.015091 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0150724 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.014682 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0145277 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0143882 |
| CCNL1 | cyclin L1 | 0.0143801 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0143441 |
| TPM3 | tropomyosin 3 | 0.0142097 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.014103 |
| ERBIN | erbb2 interacting protein | 0.0140623 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0140068 |
| KRT20 | keratin 20, type I | 0.0139405 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0136636 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0135428 |
| MYO5B | myosin VB | 0.0135244 |
| PKP4 | plakophilin 4 | 0.0134111 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.013399 |
| FLNB | filamin B, beta | 0.0133493 |
| NUP98 | nucleoporin 98kDa | 0.0132493 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0132119 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.013117 |
| LMO7 | LIM domain 7 | 0.0130927 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0130903 |
| AFDN | afadin, adherens junction formation factor | 0.013045 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0130165 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0126579 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0125352 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0123942 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0123006 |
| VMP1 | vacuole membrane protein 1 | 0.0121464 |
| PSPC1 | paraspeckle component 1 | 0.0121236 |
| PDZD8 | PDZ domain containing 8 | 0.0120866 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.012047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0120181 |
| SLTM | SAFB-like, transcription modulator | 0.0119175 |
| EHF | ets homologous factor | 0.0118441 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0117261 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0620387 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0578331 |
| RPLP1 | ribosomal protein, large, P1 | -0.0562615 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0507607 |
| TMSB10 | thymosin beta 10 | -0.0506719 |
| PTMA | prothymosin, alpha | -0.0351748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0304929 |
| RPS24 | ribosomal protein S24 | -0.0282603 |
| RPS6 | ribosomal protein S6 | -0.0272172 |
| RPS19 | ribosomal protein S19 | -0.0247102 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0236299 |
| RPL31 | ribosomal protein L31 | -0.0228287 |
| RPS5 | ribosomal protein S5 | -0.0170487 |
| RPL34 | ribosomal protein L34 | -0.0164368 |
| RPL27A | ribosomal protein L27a | -0.0161295 |
| RPL23 | ribosomal protein L23 | -0.0154383 |
| RPS23 | ribosomal protein S23 | -0.0152066 |
| RPLP0 | ribosomal protein, large, P0 | -0.014974 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0144742 |
| S100A10 | S100 calcium binding protein A10 | -0.014183 |
| VIM | vimentin | -0.0141655 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0133742 |
| RPL36A | ribosomal protein L36a | -0.0133634 |
| RPL12 | ribosomal protein L12 | -0.0133307 |
| RPL9 | ribosomal protein L9 | -0.0131114 |
| RPS16 | ribosomal protein S16 | -0.0131103 |
| RPLP2 | ribosomal protein, large, P2 | -0.0130902 |
| RPS21 | ribosomal protein S21 | -0.0119135 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0113255 |
| RPS25 | ribosomal protein S25 | -0.0108953 |
| RPL32 | ribosomal protein L32 | -0.0108078 |
| RPL19 | ribosomal protein L19 | -0.0105904 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0104341 |
| PGK1 | phosphoglycerate kinase 1 | -0.0103423 |
| RPS20 | ribosomal protein S20 | -0.0101436 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0100954 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0099576 |
| RPL8 | ribosomal protein L8 | -0.00929152 |
| GNAS | GNAS complex locus | -0.0092441 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.00921359 |
| RPL35A | ribosomal protein L35a | -0.0090127 |
| AGR2 | anterior gradient 2 | -0.00896169 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00892501 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00891966 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00868454 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.00861921 |
| RPS4X | ribosomal protein S4, X-linked | -0.00852099 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00851497 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0085045 |
| VDAC1 | voltage-dependent anion channel 1 | -0.00848996 |
| RPS11 | ribosomal protein S11 | -0.00825501 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00817663 |
| HMGB1 | high mobility group box 1 | -0.00816623 |
| RPL7 | ribosomal protein L7 | -0.00802446 |
| LYZ | lysozyme | -0.00793324 |
| SERINC3 | serine incorporator 3 | -0.00749228 |
| CCNI | cyclin I | -0.00738355 |
| RPL38 | ribosomal protein L38 | -0.00732837 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.00715687 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00706213 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.00701122 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00695956 |
| RPL11 | ribosomal protein L11 | -0.00690376 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.00675266 |
| RPS10 | ribosomal protein S10 | -0.00669405 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00661326 |
| DEK | DEK proto-oncogene | -0.00661017 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.00659986 |
| MATR3 | matrin 3 | -0.0065626 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.00653664 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.00649258 |
| LMNA | lamin A/C | -0.00642491 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.0063714 |
| RAB2A | RAB2A, member RAS oncogene family | -0.00633753 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00628649 |
| HDLBP | high density lipoprotein binding protein | -0.00619561 |
| RPL7A | ribosomal protein L7a | -0.00609767 |
| MT2A | metallothionein 2A | -0.00609512 |
| WDR45B | WD repeat domain 45B | -0.0060301 |
| RPS17 | ribosomal protein S17 | -0.00602419 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00600502 |
| ATP5MG | ATP synthase membrane subunit g | -0.00588839 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0058845 |
| C11ORF58 | chromosome 11 open reading frame 58 | -0.00584987 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00583938 |
| IER3 | immediate early response 3 | -0.00583693 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.00583436 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00575872 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00574893 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.00570416 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00568417 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.005599 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0055773 |
| CDC27 | cell division cycle 27 | -0.00553653 |
| RPL4 | ribosomal protein L4 | -0.00552155 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00550947 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.00546867 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00539616 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.005371 |
| ANXA7 | annexin A7 | -0.00530487 |
